DNMT1-mediated DNA methylation in toll-like receptor 4 (TLR4) inactivates NF-κB signal pathway-triggered pyroptotic cell death and cellular inflammation to ameliorate lipopolysaccharides (LPS)-induced osteomyelitis

The role and prospect of lysine‐specific demethylases in cancer chemoresistance

(2023) Ying‐Qi Song et al.   MEDICINAL RESEARCH REVIEWS

Marein prevented LPS-induced osteoclastogenesis by regulating the NF-κB pathway in vitro

(2022) Yuling Li et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Inhibition of PRMT5 attenuates cerebral ischemia/reperfusion–Induced inflammation and pyroptosis through suppression of NF–κB/NLRP3 axis

(2022) Xiang Wu et al.   NEUROSCIENCE LETTERS

NLRP3 and pyroptosis blockers for treating inflammatory diseases

(2022) Rebecca C. Coll et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Transcriptome Architecture of Osteoblastic Cells Infected With Staphylococcus aureus Reveals Strong Inflammatory Responses and Signatures of Metabolic and Epigenetic Dysregulation

(2022) Aurélie Nicolas et al.   Frontiers in Cellular and Infection Microbiology

Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

(2022) Bin Jiang et al.   Molecular Metabolism

Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice

(2022) Lu Luo et al.   Journal of Neuroinflammation

Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

(2022) Huanquan Chen et al.   Toxins

Gut microbiota-dependent adaptor molecule recruits DNA methyltransferase to the TLR4 gene in colonic epithelial cells to suppress inflammatory reactions

(2022) Hikari Narabayashi et al.   Frontiers in Molecular Biosciences

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation

(2021) Mohamed M. Aboudounya et al.   MEDIATORS OF INFLAMMATION

The emerging roles of RNA m6A methylation and demethylation as critical regulators of tumorigenesis, drug sensitivity, and resistance

(2021) Qing Lan et al.   CANCER RESEARCH

The emerging role of KDM5A in human cancer

(2021) Guan-Jun Yang et al.   Journal of Hematology & Oncology

DNA Methylation of TLR4, VEGFA, and DEFA5 Is Associated With Necrotizing Enterocolitis in Preterm Infants

(2021) Daphne H. Klerk et al.   Frontiers in Pediatrics

Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis

(2021) Renyikun Yuan et al.   PHARMACOLOGICAL RESEARCH

Roles of N6‐Methyladenosine Demethylase FTO in Malignant Tumors Progression

(2021) Qing-Kang Zheng et al.   OncoTargets and Therapy

Differential Expression of the TLR4 Gene in Pan-Cancer and Its Related Mechanism

(2021) Jialing Hu et al.   Frontiers in Cell and Developmental Biology

Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF-κB Suppression and NLRP3 Inflammasome Inhibition

(2021) Yuanyuan Ran et al.   Oxidative Medicine and Cellular Longevity

Urolithin A suppresses RANKL-induced osteoclastogenesis and postmenopausal osteoporosis by, suppresses inflammation and downstream NF-κB activated pyroptosis pathways

(2021) Huaqiang Tao et al.   PHARMACOLOGICAL RESEARCH

ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling

(2021) Yuan He et al.   Cell Death & Disease

Staphylococcus aureus Osteomyelitis: Bone, Bugs, and Surgery

(2020) Kenneth L. Urish et al.   INFECTION AND IMMUNITY

DNMT1 Methylation of LncRNA GAS5 Leads to Cardiac Fibroblast Pyroptosis via Affecting NLRP3 Axis

(2020) Qian She et al.   INFLAMMATION

Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis

(2020) Xue Zhang et al.   Aging-US

Tumor necrosis factor-α promotes Staphylococcus aureus-induced osteomyelitis through downregulating endothelial nitric oxide synthase

(2020) Xin Ma et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

NF-κB/TWIST1 Mediates Migration and Phagocytosis of Macrophages in the Mice Model of Implant-Associated Staphylococcus aureus Osteomyelitis

(2020) Yutian Wang et al.   Frontiers in Microbiology

TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury

(2020) Shun Xu et al.   Cell Death & Disease

NF-κB and Disease

(2020) Paola Poma   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways

(2020) Alla Zamyatina et al.   Frontiers in Immunology

The Histone Demethylase UTX/KDM6A in Cancer: Progress and Puzzles

(2019) Wolfgang A. Schulz et al.   INTERNATIONAL JOURNAL OF CANCER

The Role of Epigenetics in Autoimmune/Inflammatory Disease

(2019) Anna Elisa Andrea Surace et al.   Frontiers in Immunology

Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on TLR4 Signaling

(2019) Shofiul Azam et al.   Frontiers in Immunology

TLR4 participates in sympathetic hyperactivity Post-MI in the PVN by regulating NF-κB pathway and ROS production

(2019) Yu Wang et al.   Redox Biology

Inhibition of pyroptosis attenuates Staphylococcus aureus-induced bone injury in traumatic osteomyelitis

(2019) Xiaobo Zhu et al.   Annals of Translational Medicine

Artesunate attenuates LPS-induced osteoclastogenesis by suppressing TLR4/TRAF6 and PLCγ1-Ca2+-NFATc1 signaling pathway

(2019) Xiang-zhou Zeng et al.   ACTA PHARMACOLOGICA SINICA

Role of TLR4/NADPH oxidase 4 pathway in promoting cell death through autophagy and ferroptosis during heart failure

(2019) Xiaoqing Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease

(2019) Youliang Wang et al.   Frontiers in Endocrinology

NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

(2019) Xueliang Chen et al.   Cell Death & Disease

Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions

(2018) Nicola Kavanagh et al.   CLINICAL MICROBIOLOGY REVIEWS

The Cancer Prevention, Anti-Inflammatory and Anti-Oxidation of Bioactive Phytochemicals Targeting the TLR4 Signaling Pathway

(2018) Chung-Yi Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of pyroptosis in cardiovascular disease

(2018) Zeng Zhaolin et al.   CELL PROLIFERATION

DNA demethylation of inflammasome-associated genes is enhanced in patients with cryopyrin-associated periodic syndromes

(2017) Roser Vento-Tormo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Saturated fatty acids trigger TLR4-mediated inflammatory response

(2016) D.M. Rocha et al.   ATHEROSCLEROSIS

The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation

(2016) Monica Molteni et al.   MEDIATORS OF INFLAMMATION

DNA Methylation, Its Mediators and Genome Integrity

(2015) Huan Meng et al.   International Journal of Biological Sciences

Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling

(2014) Agnieszka Płóciennikowska et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Modelling osteomyelitis

(2012) Pietro Liò et al.   BMC BIOINFORMATICS

Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression

(2012) Sigrun R. Hofmann et al.   CLINICAL IMMUNOLOGY

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY