ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat

Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids

(2023) Ayan Chanda et al.   Cell Death & Disease

Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer

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Intermediate Filaments as Effectors of Cancer Development and Metastasis: A Focus on Keratins, Vimentin, and Nestin

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SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer

(2019) Ylenia Perone et al.   Nature Communications

Histone deacetylase 11 inhibition promotes breast cancer metastasis from lymph nodes

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Carcinosarcomas and Related Cancers: Tumors Caught in the Act of Epithelial-Mesenchymal Transition

(2018) Angela Pang et al.   JOURNAL OF CLINICAL ONCOLOGY

Cytoplasmic Intermediate Filaments in Cell Biology

(2018) Sandrine Etienne-Manneville   Annual Review of Cell and Developmental Biology

Identification of the tumour transition states occurring during EMT

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Breaking down the Contradictory Roles of Histone Deacetylase SIRT1 in Human Breast Cancer

(2018) Khaldoun Rifaï et al.   Cancers

Rho GTPase signaling complexes in cell migration and invasion

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EMT and MET: necessary or permissive for metastasis?

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EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

(2017) Tsukasa Shibue et al.   Nature Reviews Clinical Oncology

Breast tumor cell-specific knockout ofTwist1inhibits cancer cell plasticity, dissemination, and lung metastasis in mice

(2017) Yixiang Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting histone deacetylases in T-cell lymphoma

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ING1 regulates rRNA levels by altering nucleolar chromatin structure and mTOR localization

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The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated manner

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Stromal ING1 expression induces a secretory phenotype and correlates with breast cancer patient survival

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Epigenetic treatment of solid tumours: a review of clinical trials

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Reduced ING1 levels in breast cancer promotes metastasis

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Keep-ING balance: Tumor suppression by epigenetic regulation

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TWIST1Expression in Breast Cancer Cells Facilitates Bone Metastasis Formation

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New and emerging HDAC inhibitors for cancer treatment

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Suberoylanilide Hydroxamic Acid (SAHA)-Induced Dynamics of a Human Histone Deacetylase Protein Interaction Network

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Improved vectors and genome-wide libraries for CRISPR screening

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Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3

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Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo

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HDAC Inhibitors Augmented Cell Migration and Metastasis through Induction of PKCs Leading to Identification of Low Toxicity Modalities for Combination Cancer Therapy

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ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth

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Meta-Analysis of Gene Expression Signatures Defining the Epithelial to Mesenchymal Transition during Cancer Progression

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Domain Recognition of the ING1 Tumor Suppressor by a Panel of Monoclonal Antibodies

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The p53 Tumor Suppressor Is Stabilized by Inhibitor of Growth 1 (ING1) by Blocking Polyubiquitination

(2011) Subhash Thalappilly et al.   PLoS One

Deacetylase Inhibitors Dissociate the Histone-Targeting ING2 Subunit from the Sin3 Complex

(2010) Karen T. Smith et al.   CHEMISTRY & BIOLOGY

MS-275 Sensitizes TRAIL-Resistant Breast Cancer Cells, Inhibits Angiogenesis and Metastasis, and Reverses Epithelial-Mesenchymal Transition In vivo

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Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

(2009) Evanthia Galanis et al.   JOURNAL OF CLINICAL ONCOLOGY

ING2 as a Novel Mediator of Transforming Growth Factor-β-dependent Responses in Epithelial Cells

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