Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo

The variability of autophagy and cell death susceptibility

(2013) Ben Loos et al.   Autophagy

Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair

(2013) B Groselj et al.   BRITISH JOURNAL OF CANCER

Acetylation: A Novel Link between Double-Strand Break Repair and Autophagy

(2012) G. Shubassi et al.   CANCER RESEARCH

Eeyarestatin causes cervical cancer cell sensitization to bortezomib treatment by augmenting ER stress and CHOP expression

(2012) German J. Brem et al.   GYNECOLOGIC ONCOLOGY

Strategies for the discovery and development of therapies for metastatic breast cancer

(2012) Bedrich L. Eckhardt et al.   NATURE REVIEWS DRUG DISCOVERY

New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy

(2012) J S Long et al.   ONCOGENE

Mitochondrial Apoptosis and FAK Signaling Disruption by a Novel Histone Deacetylase Inhibitor, HTPB, in Antitumor and Antimetastatic Mouse Models

(2012) Jiunn-Min Shieh et al.   PLoS One

Monascuspiloin Enhances the Radiation Sensitivity of Human Prostate Cancer Cells by Stimulating Endoplasmic Reticulum Stress and Inducing Autophagy

(2012) Hui-Wen Chiu et al.   PLoS One

2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

(2012) Amaia Marcilla-Etxenike et al.   PLoS One

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

(2012) N. Gammoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Sialyltransferase Inhibitor Suppresses FAK/Paxillin Signaling and Cancer Angiogenesis and Metastasis Pathways

(2011) Jia-Yang Chen et al.   CANCER RESEARCH

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

DNA damage and autophagy

(2011) Humberto Rodriguez-Rocha et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

HDACs link the DNA damage response, processing of double-strand breaks and autophagy

(2011) Thomas Robert et al.   NATURE

Combination treatment with arsenic trioxide and irradiation enhances cell-killing effects in human fibrosarcoma cells in vitro and in vivo through induction of both autophagy and apoptosis

(2010) Hui-Wen Chiu et al.   Autophagy

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

(2010) Yuan-Ling Liu et al.   Autophagy

Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy

(2010) Manuel Rieber et al.   CANCER BIOLOGY & THERAPY

Sensitization to γ-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells

(2010) Feng Zhang et al.   CANCER BIOLOGY & THERAPY

Enhancement of Radiation Response in Osteosarcoma and Rhabomyosarcoma Cell Lines by Histone Deacetylase Inhibition

(2010) Claudia Blattmann et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Comet sensitivity in assessing DNA damage and repair in different cell cycle stages

(2010) D. G. McArt et al.   MUTAGENESIS

Combination treatment with arsenic trioxide and irradiation enhances autophagic effects in U118-MG cells through increased mitotic arrest and regulation of PI3K/Akt and ERK1/2 signaling pathways

(2009) Hui-Wen Chiu et al.   Autophagy

Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks

(2009) D. Palmieri et al.   CLINICAL CANCER RESEARCH

Targeting the endoplasmic reticulum-stress response as an anticancer strategy

(2009) Sandra J.M. Healy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ATM blocks tunicamycin-induced endoplasmic reticulum stress

(2009) Long He et al.   FEBS LETTERS

Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts

(2009) A. Baschnagel et al.   MOLECULAR CANCER THERAPEUTICS

Programmed cell death and cancer

(2009) Y Sun et al.   POSTGRADUATE MEDICAL JOURNAL

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy

(2008) Jennifer S. Carew et al.   CANCER LETTERS

A Phase II Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) in Metastatic Breast Cancer: A California Cancer Consortium Study

(2008) T. H. Luu et al.   CLINICAL CANCER RESEARCH

Synergistic Tumor-Killing Effect of Radiation and Berberine Combined Treatment in Lung Cancer: The Contribution of Autophagic Cell Death

(2008) Pei-ling Peng et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

Resveratrol inhibits heregulin-β1-mediated matrix metalloproteinase-9 expression and cell invasion in human breast cancer cells☆

(2007) F TANG et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY