标题
Nuclear mechanosensing of the aortic endothelium in health and disease
作者
关键词
-
出版物
Disease Models & Mechanisms
Volume 16, Issue 10, Pages -
出版商
The Company of Biologists
发表日期
2023-11-01
DOI
10.1242/dmm.050361
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechanosignals in abdominal aortic aneurysms
- (2023) Christiana Lowis et al. Frontiers in Cardiovascular Medicine
- Flow-induced reprogramming of endothelial cells in atherosclerosis
- (2023) Ian A. Tamargo et al. Nature Reviews Cardiology
- Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow
- (2023) Emy Bosseboeuf et al. Science Signaling
- Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression
- (2023) Frederic Li Mow Chee et al. Nature Communications
- Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation
- (2023) Danielle B Buglak et al. eLife
- PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing
- (2023) Eulashini Chuntharpursat-Bon et al. Communications Biology
- Progerin-expressing endothelial cells are unable to adapt to shear stress
- (2022) Brooke E. Danielsson et al. BIOPHYSICAL JOURNAL
- Cilia proteins are biomarkers of altered flow in the vasculature
- (2022) Ankan Gupta et al. JCI Insight
- Transcriptional Evaluation of the Ductus Arteriosus at the Single-Cell Level Uncovers a Requirement for Vim (Vimentin) for Complete Closure
- (2022) Jocelynda Salvador et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation
- (2022) Mengping Jia et al. CIRCULATION RESEARCH
- Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites
- (2022) Roman Tsaryk et al. Scientific Reports
- A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells
- (2022) Brian G. Coon et al. JOURNAL OF CELL BIOLOGY
- YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS–STING
- (2022) Hanna Lucie Sladitschek-Martens et al. NATURE
- Mechanical force application to the nucleus regulates nucleocytoplasmic transport
- (2022) Ion Andreu et al. NATURE CELL BIOLOGY
- The spectrin cytoskeleton integrates endothelial mechanoresponses
- (2022) Sivakami Mylvaganam et al. NATURE CELL BIOLOGY
- SOX9 reprograms endothelial cells by altering the chromatin landscape
- (2022) Bettina M Fuglerud et al. NUCLEIC ACIDS RESEARCH
- Glycocalyx heparan sulfate cleavage promotes endothelial cell angiopoietin-2 expression by impairing shear stress–related AMPK/FoxO1 signaling
- (2022) Robert P. Richter et al. JCI Insight
- Chromatin condensation regulates endothelial cell adaptation to shear stress
- (2022) Brooke E. Danielsson et al. MOLECULAR BIOLOGY OF THE CELL
- Genetics and mechanisms of thoracic aortic disease
- (2022) Elizabeth Chou et al. Nature Reviews Cardiology
- KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress
- (2022) Jan-Renier Moonen et al. Nature Communications
- JAG1-NOTCH4 mechanosensing drives atherosclerosis
- (2022) Celine Souilhol et al. Science Advances
- Endothelial dysfunction in Marfan syndrome mice is restored by resveratrol
- (2022) Arnout Mieremet et al. Scientific Reports
- MEF2 (Myocyte Enhancer Factor 2) Is Essential for Endothelial Homeostasis and the Atheroprotective Gene Expression Program
- (2021) Yao Wei Lu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Flow-mediated vasodilation through mechanosensitive G protein-coupled receptors in endothelial cells
- (2021) Yong Hu et al. TRENDS IN CARDIOVASCULAR MEDICINE
- The LINC complex is required for endothelial cell adhesion and adaptation to shear stress and cyclic stretch
- (2021) Kevin B. Denis et al. MOLECULAR BIOLOGY OF THE CELL
- Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway
- (2021) Vedanta Mehta et al. Science Advances
- YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment
- (2020) Paul R. Coleman et al. Cell Communication and Signaling
- The guidance receptor plexin D1 is a mechanosensor in endothelial cells
- (2020) Vedanta Mehta et al. NATURE
- Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
- (2020) Eric Engelbrecht et al. eLife
- iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome
- (2020) Leigh Atchison et al. Stem Cell Reports
- Vascular endothelium–targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model
- (2020) Shimin Sun et al. Science Advances
- Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
- (2020) Michele M. Nava et al. CELL
- Endothelial-to-Mesenchymal Transition, Vascular Inflammation, and Atherosclerosis
- (2020) Pei-Yu Chen et al. Frontiers in Cardiovascular Medicine
- Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study
- (2020) Aitor Andueza et al. Cell Reports
- Disturbed flow–induced Gs-mediated signaling protects against endothelial inflammation and atherosclerosis
- (2020) Akiko Nakayama et al. JCI Insight
- c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow
- (2019) Bochuan Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Shear-Induced CCN1 Promotes Atheroprone Endothelial Phenotypes and Atherosclerosis
- (2019) Pei-Ling Hsu et al. CIRCULATION
- Identification of atheroprone shear stress responsive regulatory elements in endothelial cells
- (2019) Olga Bondareva et al. CARDIOVASCULAR RESEARCH
- GATA4-Twist1 Signalling in Disturbed Flow-Induced Atherosclerosis
- (2019) Marwa Mahmoud et al. CARDIOVASCULAR DRUGS AND THERAPY
- Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (Krüppel-Like Factor 4)-Mediated Histone Modifications
- (2019) Ming He et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Endothelial-to-Mesenchymal Transition
- (2019) Joyce Bischoff CIRCULATION RESEARCH
- Genetic correlates of wall shear stress in a patient-specific 3D-printed cerebral aneurysm model
- (2019) Michael R Levitt et al. Journal of NeuroInterventional Surgery
- Time-resolved 3-dimensional magnetic resonance phase contrast imaging (4D Flow MRI) reveals altered blood flow patterns in the ascending aorta of patients with valve-sparing aortic root replacement
- (2019) Thekla H. Oechtering et al. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
- Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations
- (2019) Aditya S. Kalluri et al. CIRCULATION
- The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis
- (2019) Suowen Xu et al. EUROPEAN HEART JOURNAL
- Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure
- (2019) Andras Iring et al. JOURNAL OF CLINICAL INVESTIGATION
- Mechanically activated piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis
- (2019) Anne-Laure Duchemin et al. eLife
- A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction
- (2019) Gillian Douglas et al. CARDIOVASCULAR RESEARCH
- Helix 8 is the essential structural motif of mechanosensitive GPCRs
- (2019) Serap Erdogmus et al. Nature Communications
- Role of endothelial primary cilia as fluid mechanosensors on vascular health
- (2018) Vincent Z. Luu et al. ATHEROSCLEROSIS
- Endothelial–mesenchymal transition in atherosclerosis
- (2018) Celine Souilhol et al. CARDIOVASCULAR RESEARCH
- GPR68 Senses Flow and Is Essential for Vascular Physiology
- (2018) Jie Xu et al. CELL
- Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II–Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic AneurysmNovelty and Significance
- (2018) Surawee Chuaiphichai et al. HYPERTENSION
- Cell‑specific histone modifications in atherosclerosis (Review)
- (2018) Wanlin Jiang et al. Molecular Medicine Reports
- Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects
- (2018) Suowen Xu et al. Theranostics
- Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation
- (2018) Julián Albarrán-Juárez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse
- (2018) Selma Osmanagic-Myers et al. JOURNAL OF CLINICAL INVESTIGATION
- The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
- (2018) Lei Chang et al. NATURE
- Emerging roles of mechanical forces in chromatin regulation
- (2017) Yekaterina A. Miroshnikova et al. JOURNAL OF CELL SCIENCE
- NOTCH1 is a mechanosensor in adult arteries
- (2017) Julia J. Mack et al. Nature Communications
- Endothelial primary cilia inhibit atherosclerosis
- (2016) Colin Dinsmore et al. EMBO REPORTS
- Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow
- (2016) Li Wang et al. NATURE
- Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis
- (2016) Kuei-Chun Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex
- (2015) Brian G. Coon et al. JOURNAL OF CELL BIOLOGY
- HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1to limit vascular inflammation
- (2015) Sylvain Galvani et al. Science Signaling
- Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point
- (2015) Nicolas Baeyens et al. eLife
- HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1to limit vascular inflammation
- (2015) Sylvain Galvani et al. Science Signaling
- 4D phase contrast MRI in the preterm infant: visualisation of patent ductus arteriosus
- (2014) Kathryn M Broadhouse et al. Archives of Disease in Childhood-Fetal and Neonatal Edition
- Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1
- (2014) Jing Zhou et al. Cellular and Molecular Bioengineering
- Hemodynamic Disturbed Flow Induces Differential DNA Methylation of Endothelial Kruppel-Like Factor 4 Promoter In Vitro and In Vivo
- (2014) Yi-Zhou Jiang et al. CIRCULATION RESEARCH
- Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration
- (2014) Samantha J. King et al. Cytoskeleton
- Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis
- (2014) Jessilyn Dunn et al. JOURNAL OF CLINICAL INVESTIGATION
- Piezo1 integration of vascular architecture with physiological force
- (2014) Jing Li et al. NATURE
- Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus
- (2014) Christophe Guilluy et al. NATURE CELL BIOLOGY
- Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling
- (2014) Nicolas Baeyens et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging topic: Flow-related epigenetic regulation of endothelial phenotype through DNA methylation
- (2014) Peter F. Davies et al. VASCULAR PHARMACOLOGY
- Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development
- (2014) Jacky G. Goetz et al. Cell Reports
- Pharmacological Inhibitor of Notch Signaling Stabilizes the Progression of Small Abdominal Aortic Aneurysm in a Mouse Model
- (2014) Jeeyun Cheng et al. Journal of the American Heart Association
- Endothelial Shc Regulates Arteriogenesis Through Dual Control of Arterial Specification and Inflammation via the Notch and Nuclear Factor-κ–Light-Chain-Enhancer of Activated B-Cell Pathways
- (2013) Daniel T. Sweet et al. CIRCULATION RESEARCH
- Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1
- (2013) Daniel E. Conway et al. CURRENT BIOLOGY
- Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
- (2013) J. Swift et al. SCIENCE
- The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction
- (2013) Allison B. Chambliss et al. Scientific Reports
- The nucleus of endothelial cell as a sensor of blood flow direction
- (2013) E. Tkachenko et al. Biology Open
- Inhibition of Notch1 Signaling Reduces Abdominal Aortic Aneurysm in Mice by Attenuating Macrophage-Mediated Inflammation
- (2012) Chetan P. Hans et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Role of nesprin-1 in nuclear deformation in endothelial cells under static and uniaxial stretching conditions
- (2012) Toshiro Anno et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Flow-Regulated Endothelial S1P Receptor-1 Signaling Sustains Vascular Development
- (2012) Bongnam Jung et al. DEVELOPMENTAL CELL
- Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow
- (2012) D.-Y. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endothelial Cell–Specific Deficiency of Ang II Type 1a Receptors Attenuates Ang II–Induced Ascending Aortic Aneurysms in LDL Receptor −/− Mice
- (2011) Debra L. Rateri et al. CIRCULATION RESEARCH
- Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization
- (2011) Joshua T. Morgan et al. MOLECULAR BIOLOGY OF THE CELL
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging
- (2010) Michelle Olive et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Actomyosin Tension Exerted on the Nucleus through Nesprin-1 Connections Influences Endothelial Cell Adhesion, Migration, and Cyclic Strain-Induced Reorientation
- (2010) T.J. Chancellor et al. BIOPHYSICAL JOURNAL
- Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23
- (2010) J. Erdmann et al. EUROPEAN HEART JOURNAL
- In vivo assessment of wall shear stress in the atherosclerotic aorta using flow-sensitive 4D MRI
- (2010) Andreas Harloff et al. MAGNETIC RESONANCE IN MEDICINE
- Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS
- (2009) W. Wang et al. BLOOD
- Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades
- (2009) Wissam A. AbouAlaiwi et al. CIRCULATION RESEARCH
- Effects of Disturbed Flow on Endothelial Cells
- (2008) Shu Chien ANNALS OF BIOMEDICAL ENGINEERING
- Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor–Deficient Mice
- (2008) Reema Goel et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1
- (2008) Surya M. Nauli et al. CIRCULATION
- Nuclear Shape, Mechanics, and Mechanotransduction
- (2008) Kris Noel Dahl et al. CIRCULATION RESEARCH
- Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation
- (2008) Yunhao Liu et al. JOURNAL OF CELL BIOLOGY
- Mechanotransduction in vascular physiology and atherogenesis
- (2008) Cornelia Hahn et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis
- (2007) Kim Van der Heiden et al. ATHEROSCLEROSIS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started