The guidance receptor plexin D1 is a mechanosensor in endothelial cells

Rapid flow-induced activation of Gαq/11 is independent of Piezo1 activation

(2019) Nathaniel G. dela Paz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

GPR68 Senses Flow and Is Essential for Vascular Physiology

(2018) Jie Xu et al.   CELL

Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation

(2018) Julián Albarrán-Juárez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK

(2017) Jennifer L. Bays et al.   NATURE CELL BIOLOGY

Endothelial Mechanosignaling: Does One Sensor Fit All?

(2016) Chris Givens et al.   ANTIOXIDANTS & REDOX SIGNALING

Pulling on my heartstrings

(2016) Margaret E. McCormick et al.   CURRENT OPINION IN HEMATOLOGY

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural Basis for Plexin Activation and Regulation

(2016) Youxin Kong et al.   NEURON

Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies

(2016) Kei Suzuki et al.   PLoS One

Blood flow mechanics in cardiovascular development

(2015) Francesco Boselli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic ForcesNovelty and Significance

(2015) Congqing Wu et al.   CIRCULATION RESEARCH

Semaphorin signalling during development

(2014) B. C. Jongbloets et al.   DEVELOPMENT

Semaphorin 3d and Semaphorin 3e Direct Endothelial Motility through Distinct Molecular Signaling Pathways

(2014) Haig Aghajanian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling

(2014) Nicolas Baeyens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells

(2014) Caitlin Collins et al.   Nature Communications

Localized Tensional Forces on PECAM-1 Elicit a Global Mechanotransduction Response via the Integrin-RhoA Pathway

(2012) Caitlin Collins et al.   CURRENT BIOLOGY

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Structural insights into semaphorins and their receptors

(2012) Christian Siebold et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Diverse functions for the semaphorin receptor PlexinD1 in development and disease

(2010) Carl M. Gay et al.   DEVELOPMENTAL BIOLOGY

Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

(2010) A. Sakurai et al.   MOLECULAR AND CELLULAR BIOLOGY

Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects

(2008) Ying Zhang et al.   DEVELOPMENTAL BIOLOGY

Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation

(2008) Yunhao Liu et al.   JOURNAL OF CELL BIOLOGY

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY