Ca2+ signalling: A common language for organelles crosstalk in Parkinson's disease

Mitochondrial complex I deficiency and Parkinson disease

(2023) Janelle Drouin-Ouellet   NATURE REVIEWS NEUROSCIENCE

Novel insights into Parkin-mediated mitochondrial dysfunction and neuroinflammation in Parkinson's disease

(2023) Sandro L. Pereira et al.   CURRENT OPINION IN NEUROBIOLOGY

Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism

(2023) Pascale Baden et al.   Nature Communications

Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson’s disease

(2023) Wesley Peng et al.   Science Advances

Mitochondria, energy, and metabolism in neuronal health and disease

(2022) Diogo Trigo et al.   FEBS LETTERS

The MFN1 and MFN2 mitofusins promote clustering between mitochondria and peroxisomes

(2022) Yinbo Huo et al.   Communications Biology

Molecular genetics of Parkinson’s disease: Contributions and global trends

(2022) Manabu Funayama et al.   JOURNAL OF HUMAN GENETICS

The ER protein Creld regulates ER-mitochondria contact dynamics and respiratory complex 1 activity

(2022) Marie Paradis et al.   Science Advances

Ca 2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons

(2022) Enrico Zampese et al.   Science Advances

The PTPIP51 coiled-coil domain is important in VAPB binding, formation of ER-mitochondria contacts and IP3 receptor delivery of Ca2+ to mitochondria

(2022) Gábor M. Mórotz et al.   Frontiers in Cell and Developmental Biology

The Hidden Cell-to-Cell Trail of α-Synuclein Aggregates

(2022) Sandesh Neupane et al.   JOURNAL OF MOLECULAR BIOLOGY

Lipid Droplet Contact Sites in Health and Disease

(2021) Eva Herker et al.   TRENDS IN CELL BIOLOGY

Interorganelle communication, aging, and neurodegeneration

(2021) Maja Petkovic et al.   GENES & DEVELOPMENT

Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease

(2021) Soojin Kim et al.   Nature Communications

Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis

(2021) Irene Anastasia et al.   Cell Reports

The dynamics of nigrostriatal system damage and neurobehavioral changes in the rotenone rat model of Parkinson’s disease

(2021) Dmitry Troshev et al.   BRAIN RESEARCH BULLETIN

Overexpression of α‐synuclein inhibits mitochondrial Ca 2+ trafficking between the endoplasmic reticulum and mitochondria through MAMs by altering the GRP75–IP3R interaction

(2021) Adolfo Garcia Erustes et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Differential mitochondrial roles for α-synuclein in DRP1-dependent fission and PINK1/Parkin-mediated oxidation

(2021) Thomas J. Krzystek et al.   Cell Death & Disease

A transcriptome-wide association study identifies susceptibility genes for Parkinson’s disease

(2021) Shi Yao et al.   npj Parkinsons Disease

PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness

(2021) Nicolas Rabas et al.   JOURNAL OF CELL BIOLOGY

Disruption of mitochondrial complex I induces progressive parkinsonism

(2021) Patricia González-Rodríguez et al.   NATURE

The cell biology of mitochondrial membrane dynamics

(2020) Marta Giacomello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s Disease

(2020) Giacomo Monzio Compagnoni et al.   MOLECULAR NEUROBIOLOGY

Contact-ID, a tool for profiling organelle contact sites, reveals regulatory proteins of mitochondrial-associated membrane formation

(2020) Chulhwan Kwak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocerebrosidase Defects as a Major Risk Factor for Parkinson’s Disease

(2020) Micol Avenali et al.   Frontiers in Aging Neuroscience

Current and Emerging Approaches for Studying Inter-Organelle Membrane Contact Sites

(2020) Xue Huang et al.   Frontiers in Cell and Developmental Biology

Tether Me, Tether Me Not—Dynamic Organelle Contact Sites in Metabolic Rewiring

(2020) Maria Bohnert   DEVELOPMENTAL CELL

PINK 1 phosphorylates Drp1 S616 to regulate mitophagy‐independent mitochondrial dynamics

(2020) Hailong Han et al.   EMBO REPORTS

Mitochondria-lysosome contacts regulate mitochondrial Ca2+dynamics via lysosomal TRPML1

(2020) Wesley Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of Parkinson's disease

(2020) Ajith Cherian et al.   ACTA NEUROLOGICA BELGICA

The Parkinson's Disease Genome‐Wide Association Study Locus Browser

(2020) Francis P. Grenn et al.   MOVEMENT DISORDERS

The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease

(2020) Dajana Grossmann et al.   Frontiers in Neurology

Mitochondrial Metabolism, Contact Sites and Cellular Calcium Signaling: Implications for Tumorigenesis

(2020) Roberta Peruzzo et al.   Cancers

Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441G mice

(2020) Huifang Liu et al.   Autophagy

ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress

(2020) Stephanie Vrijsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity

(2019) Patricia Gómez-Suaga et al.   Acta Neuropathologica Communications

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Regulation and Function of Mitochondria–Lysosome Membrane Contact Sites in Cellular Homeostasis

(2019) Yvette C. Wong et al.   TRENDS IN CELL BIOLOGY

The Expanding and Unexpected Functions of Mitochondria Contact Sites

(2019) Laura L. Lackner   TRENDS IN CELL BIOLOGY

Emerging therapies in Parkinson disease — repurposed drugs and new approaches

(2019) Ahmad Elkouzi et al.   Nature Reviews Neurology

VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation

(2019) Sandra Muñoz-Braceras et al.   Disease Models & Mechanisms

The autophagic degradation of cytosolic pools of peroxisomal proteins by a new selective pathway

(2019) Xiaofeng Wang et al.   Autophagy

Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility

(2019) Wondwossen M Yeshaw et al.   eLife

The physiological role of α‐synuclein and its relationship to Parkinson’s Disease

(2019) David Sulzer et al.   JOURNAL OF NEUROCHEMISTRY

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

(2019) Ya-Cheng Liao et al.   CELL

splitGFP Technology Reveals Dose-Dependent ER-Mitochondria Interface Modulation by α-Synuclein A53T and A30P Mutants

(2019) Tito Calì et al.   Cells

Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes

(2019) Fumika Koyano et al.   EMBO REPORTS

DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1

(2019) Yi Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery

(2019) Souvik Modi et al.   Nature Communications

LRRK 2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK ‐mediated ubiquitination pathway

(2019) Toshihiko Toyofuku et al.   EMBO JOURNAL

LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same

(2019) Daniel C. Berwick et al.   Molecular Neurodegeneration

The role of dopamine in the pathogenesis of GBA1-linked Parkinson's disease

(2019) Lena F. Burbulla et al.   NEUROBIOLOGY OF DISEASE

Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson’s models

(2018) Atossa Shaltouki et al.   ACTA NEUROPATHOLOGICA

Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress

(2018) Jaime N. Guzman et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

(2018) Yvette C. Wong et al.   NATURE

The multifaceted contributions of mitochondria to cellular metabolism

(2018) Jessica B. Spinelli et al.   NATURE CELL BIOLOGY

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

(2018) Marthe H. R. Ludtmann et al.   Nature Communications

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

The Close Encounter Between Alpha-Synuclein and Mitochondria

(2018) Mattia Vicario et al.   Frontiers in Neuroscience

Mitochondrial Dysfunction and Mitophagy Defect Triggered by Heterozygous GBA Mutations

(2018) Hongyu Li et al.   Autophagy

The peroxisome: an update on mysteries 2.0

(2018) Markus Islinger et al.   HISTOCHEMISTRY AND CELL BIOLOGY

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts

(2018) Cristina Parrado-Fernández et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation of Endoplasmic Reticulum-Mitochondria contacts by Parkin via Mfn2

(2018) Valentina Basso et al.   PHARMACOLOGICAL RESEARCH

LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis

(2018) Tomoya Eguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Emerging Evidence of the Parkinson Pandemic

(2018) E. Ray Dorsey et al.   Journal of Parkinsons Disease

The Peroxisome-Mitochondria Connection: How and Why?

(2017) Marc Fransen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants

(2017) Manish Verma et al.   JOURNAL OF NEUROSCIENCE

On the role of Mitofusin 2 in endoplasmic reticulum–mitochondria tethering

(2017) Riccardo Filadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER-mitochondria tethering by PDZD8 regulates Ca2+dynamics in mammalian neurons

(2017) Yusuke Hirabayashi et al.   SCIENCE

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

(2017) Hui-Fang Liu et al.   Scientific Reports

DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy

(2017) Chuan-Ying Xu et al.   Frontiers in Aging Neuroscience

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

(2017) Dominika Truban et al.   Journal of Parkinsons Disease

The MPTP Story

(2017) J. William Langston   Journal of Parkinsons Disease

Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

(2017) Victoria Hung et al.   eLife

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

The genetic background of Parkinson's disease: current progress and future prospects

(2016) K. Kalinderi et al.   ACTA NEUROLOGICA SCANDINAVICA

Enjoy the Trip: Calcium in Mitochondria Back and Forth

(2016) Diego De Stefani et al.   Annual Review of Biochemistry

In vitro aging promotes endoplasmic reticulum (ER)-mitochondria Ca 2+ cross talk and loss of store-operated Ca 2+ entry (SOCE) in rat hippocampal neurons

(2016) María Calvo-Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

No peroxisome is an island — Peroxisome contact sites

(2016) Nadav Shai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Calcium regulation in mouse mesencephalic neurons—Differential roles of Na+/Ca2+ exchanger, mitochondria and endoplasmic reticulum

(2016) Pei-Chun Wu et al.   CELL CALCIUM

Mitochondria-associated ER membranes and Alzheimer disease

(2016) Estela Area-Gomez et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

(2016) Michal Eisenberg-Bord et al.   DEVELOPMENTAL CELL

Mitochondrial dysfunction in Parkinson's disease

(2016) Anindita Bose et al.   JOURNAL OF NEUROCHEMISTRY

Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase

(2016) M. H. R. Ludtmann et al.   JOURNAL OF NEUROSCIENCE

Activation of  -Glucocerebrosidase Reduces Pathological  -Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons

(2016) J. R. Mazzulli et al.   JOURNAL OF NEUROSCIENCE

The Emerging Network of Mitochondria-Organelle Contacts

(2016) Andrew Murley et al.   MOLECULAR CELL

ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis

(2016) Jinjiang Fan et al.   MOLECULAR ENDOCRINOLOGY

Mitochondria-Associated Membranes (MAMs): Overview and Its Role in Parkinson’s Disease

(2016) M. Rodríguez-Arribas et al.   MOLECULAR NEUROBIOLOGY

Pathology: The prion principle

(2016) Simon Makin   NATURE

Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis

(2016) Giovanni Manfredi et al.   NEUROBIOLOGY OF DISEASE

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

(2016) Deborah Naon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

(2016) Roberto Di Maio et al.   Science Translational Medicine

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

(2016) Sebastien Paillusson et al.   TRENDS IN NEUROSCIENCES

Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease

(2016) I Celardo et al.   Cell Death & Disease

Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson’s Disease

(2016) Katharina E. Rosenbusch et al.   Parkinsons Disease

Glucocerebrosidase and Parkinson disease: Recent advances

(2015) Anthony H.V. Schapira   MOLECULAR AND CELLULAR NEUROSCIENCE

Parkinson's disease as a member of Prion-like disorders

(2015) Maria Eugenia Herva et al.   VIRUS RESEARCH

At the right distance: ER-mitochondria juxtaposition in cell life and death

(2014) Deborah Naon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Activity-Driven Local ATP Synthesis Is Required for Synaptic Function

(2014) Vidhya Rangaraju et al.   CELL

A new split-GFP-based probe reveals DJ-1 translocation into the mitochondrial matrix to sustain ATP synthesis upon nutrient deprivation

(2014) Tito Calì et al.   HUMAN MOLECULAR GENETICS

 -Synuclein Is Localized to Mitochondria-Associated ER Membranes

(2014) C. Guardia-Laguarta et al.   JOURNAL OF NEUROSCIENCE

iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis

(2014) David C. Schöndorf et al.   Nature Communications

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca2+ transfer to sustain cell bioenergetics

(2013) Tito Calì et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Metabolic functions of peroxisomes in health and disease

(2013) Ronald J.A. Wanders   BIOCHIMIE

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

(2013) Laura D. Osellame et al.   Cell Metabolism

Calcium and Endoplasmic Reticulum-Mitochondria Tethering in Neurodegeneration

(2013) Tito Calì et al.   DNA AND CELL BIOLOGY

The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering

(2013) D. Ottolini et al.   HUMAN MOLECULAR GENETICS

In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM)

(2013) Chloe N. Poston et al.   Journal of Proteomics

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction

(2013) Laurie H. Sanders et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective Function of DJ-1 in Parkinson’s Disease

(2013) Hiroyoshi Ariga et al.   Oxidative Medicine and Cellular Longevity

The Role of Autophagy in Parkinson's Disease

(2013) M. A. Lynch-Day et al.   Cold Spring Harbor Perspectives in Medicine

DJ-1 promotes the proteasomal degradation of Fis1: implications of DJ-1 in neuronal protection

(2012) Qiang Zhang et al.   BIOCHEMICAL JOURNAL

G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

(2012) Tatiana D. Papkovskaia et al.   HUMAN MOLECULAR GENETICS

Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology

(2012) Kenta Onoue et al.   JOURNAL OF CELL SCIENCE

The link between the GBA gene and parkinsonism

(2012) Ellen Sidransky et al.   LANCET NEUROLOGY

Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage

(2012) Michael W.J. Cleeter et al.   NEUROCHEMISTRY INTERNATIONAL

DJ-1 Null Dopaminergic Neuronal Cells Exhibit Defects in Mitochondrial Function and Structure: Involvement of Mitochondrial Complex I Assembly

(2012) Jun Young Heo et al.   PLoS One

A Deleterious Mutation in DNAJC6 Encoding the Neuronal-Specific Clathrin-Uncoating Co-Chaperone Auxilin, Is Associated with Juvenile Parkinsonism

(2012) Simon Edvardson et al.   PLoS One

A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

(2011) Alexander Zimprich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

VPS35 Mutations in Parkinson Disease

(2011) Carles Vilariño-Güell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis

(2011) Amr Al-Saif et al.   ANNALS OF NEUROLOGY

Toxin Models of Mitochondrial Dysfunction in Parkinson's Disease

(2011) Terina N. Martinez et al.   ANTIOXIDANTS & REDOX SIGNALING

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria

(2011) D De Stefani et al.   CELL DEATH AND DIFFERENTIATION

The Mitochondrial Cascade Hypothesis for Parkinsons Disease

(2011) Sandra M. Cardoso   CURRENT PHARMACEUTICAL DESIGN

LRRK2 Parkinson disease mutations enhance its microtubule association

(2011) Lauren R. Kett et al.   HUMAN MOLECULAR GENETICS

Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein

(2011) Ken Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Mitochondrial Calcium Sensitivity and Abnormal Expression of Innate Immunity Genes Precede Dopaminergic Defects in Pink1-Deficient Mice

(2011) Ravi S. Akundi et al.   PLoS One

DJ-1 mediates paraquat-induced dopaminergic neuronal cell death

(2011) Hyun Joo Kwon et al.   TOXICOLOGY LETTERS

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

(2010) I. Irrcher et al.   HUMAN MOLECULAR GENETICS

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

(2010) Kelly Jean Thomas et al.   HUMAN MOLECULAR GENETICS

Characterization of the Properties of a Novel Mutation in VAPB in Familial Amyotrophic Lateral Sclerosis

(2010) Han-Jou Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

(2010) Ashley R. Winslow et al.   JOURNAL OF CELL BIOLOGY

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin

(2010) E. Ziviani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease

(2010) B. Zheng et al.   Science Translational Medicine

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson’s disease by disturbing calcium flux

(2009) Roberta Marongiu et al.   JOURNAL OF NEUROCHEMISTRY

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein abnormalities in mouse models of peroxisome biogenesis disorders

(2009) Eugenia Yakunin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

MUTATIONS IN GBA ARE ASSOCIATED WITH FAMILIAL PARKINSON DISEASE SUSCEPTIBILITY AND AGE AT ONSET

(2009) E. Sidransky et al.   NEUROLOGY

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Linkage Analysis of a Parkinsonian-Pyramidal Syndrome Pedigree by 500 K SNP Arrays

(2008) Seyedmehdi Shojaee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Characterization of PLA2G6 as a locus for dystonia-parkinsonism

(2008) Coro Paisan-Ruiz et al.   ANNALS OF NEUROLOGY

Oxidative Stress Involvement in α-Synuclein Oligomerization in Parkinson's Disease Cybrids

(2008) A. Raquel Esteves et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain

(2008) Latha Devi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

(2008) Eunsung Junn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Bap31 Is an Itinerant Protein That Moves between the Peripheral Endoplasmic Reticulum (ER) and a Juxtanuclear Compartment Related to ER-associated Degradation

(2008) Yuichi Wakana et al.   MOLECULAR BIOLOGY OF THE CELL

Research in motion: the enigma of Parkinson's disease pathology spread

(2008) Patrik Brundin et al.   NATURE REVIEWS NEUROSCIENCE

FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

(2008) A. D. Fonzo et al.   NEUROLOGY