Cinchonine exerts anti-tumor and immunotherapy sensitizing effects in lung cancer by impairing autophagic-lysosomal degradation
出版年份 2023 全文链接
标题
Cinchonine exerts anti-tumor and immunotherapy sensitizing effects in lung cancer by impairing autophagic-lysosomal degradation
作者
关键词
-
出版物
BIOMEDICINE & PHARMACOTHERAPY
Volume 164, Issue -, Pages 114980
出版商
Elsevier BV
发表日期
2023-06-08
DOI
10.1016/j.biopha.2023.114980
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Immunogenic hypofractionated radiotherapy sensitising head and neck squamous cell carcinoma to anti-PD-L1 therapy in MDSC-dependent manner
- (2023) Liang Mao et al. BRITISH JOURNAL OF CANCER
- Combination strategies with PD-1/PD-L1 blockade: current advances and future directions
- (2022) Ming Yi et al. Molecular Cancer
- A Paradigm of Cancer Immunotherapy Based on 2-[18F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect
- (2022) Xuejun Wen et al. CLINICAL CANCER RESEARCH
- 13-Methyl-palmatrubine shows an anti-tumor role in non-small cell lung cancer via shifting M2 to M1 polarization of tumor macrophages
- (2022) Zhihui Wu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 2.2021
- (2021) David S. Ettinger et al. Journal of the National Comprehensive Cancer Network
- G Protein-Coupled Estrogen Receptor in Cancer and Stromal Cells: Functions and Novel Therapeutic Perspectives
- (2021) Richard A. Pepermans et al. Cells
- Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer
- (2021) Xiongjie Zhu et al. CARBOHYDRATE POLYMERS
- Autophagy in major human diseases
- (2021) Daniel J Klionsky et al. EMBO JOURNAL
- Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer
- (2021) Chunfeng Xie et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics
- (2021) Dhiraj Kumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitative immunohistochemistry (IHC) analysis of biomarker combinations for human esophageal squamous cell carcinoma
- (2021) Jiebing Gao et al. Annals of Translational Medicine
- Full-coverage regulations of autophagy by ROS: from induction to maturation
- (2021) Jing Zhou et al. Autophagy
- Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis
- (2021) Jan Stein et al. Oxidative Medicine and Cellular Longevity
- Yeast β-D-glucan exerts anti-tumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis
- (2020) Ningning Wang et al. Redox Biology
- Lysosome biology in autophagy
- (2020) Willa Wen-You Yim et al. Cell Discovery
- Autophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis
- (2020) Yu-Qin Di et al. Autophagy
- PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer
- (2020) Brian Diskin et al. NATURE IMMUNOLOGY
- Natural Compounds with Potential to Modulate Cancer Therapies and Self-Reactive Immune Cells
- (2020) Rhiane Moody et al. Cancers
- Repurposing of quinoline alkaloids identifies their ability to induce sub G0/G1 phase cell cycle arrest and enhance doxorubicin‐induced apoptosis in cervical and hepatocellular carcinoma cells
- (2020) Mohamed El‐Mesery et al. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
- Autophagosomes are formed at a distinct cellular structure
- (2020) David M. Hollenstein et al. CURRENT OPINION IN CELL BIOLOGY
- Cinchonine inhibits osteoclast differentiation by regulating TAK1 and AKT, and promotes osteogenesis
- (2020) You‐Jin Jo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management
- (2020) Tulasi Yadati et al. Cells
- Autophagy and Its Regulators in Response to Stress in Plants
- (2020) Wanlong Su et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting autophagy to overcome drug resistance: further developments
- (2020) Haocai Chang et al. Journal of Hematology & Oncology
- Regulation of PD-L1 Expression by NF-κB in Cancer
- (2020) Fabrizio Antonangeli et al. Frontiers in Immunology
- The relationship between autophagy and the immune system and its applications for tumor immunotherapy
- (2019) Guan-Min Jiang et al. Molecular Cancer
- Autophagy inhibition enhances PD-L1 expression in gastric cancer
- (2019) Xiaojuan Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Role of tumor and host autophagy in cancer metabolism
- (2019) Laura Poillet-Perez et al. GENES & DEVELOPMENT
- Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy
- (2019) Preeti Gupta et al. BIOMEDICINE & PHARMACOTHERAPY
- iNOS Interacts with Autophagy Receptor p62 and is Degraded by Autophagy in Macrophages
- (2019) Jing Wang et al. Cells
- PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling
- (2019) Hongmin Gao et al. BIOSCIENCE REPORTS
- Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer
- (2018) Lu Zhang et al. Autophagy
- Autophagy Inhibitor (LY294002) and 5-fluorouracil (5-FU) Combination-Based Nanoliposome for Enhanced Efficacy Against Esophageal Squamous Cell Carcinoma
- (2018) Ye Feng et al. Nanoscale Research Letters
- Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6
- (2017) Yonghao Qi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Cathepsins in digestive cancers
- (2017) Siyuan Chen et al. Oncotarget
- Research progress of hydroxychloroquine and autophagy inhibitors on cancer
- (2016) Ting-Ting Shi et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity Cancers
- (2016) E. C. Moore et al. Cancer Immunology Research
- Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma
- (2015) Brian A. Boone et al. ANNALS OF SURGICAL ONCOLOGY
- Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells
- (2015) Xuejiao Zhao et al. Autophagy
- A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission
- (2015) Jing Zhou et al. Autophagy
- Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion
- (2015) Caroline Mauvezin et al. Autophagy
- Autophagy, Metabolism, and Cancer
- (2015) E. White et al. CLINICAL CANCER RESEARCH
- The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation
- (2014) Yuanzhi Lao et al. Autophagy
- Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma
- (2014) Fatma E. Mohamed et al. LIVER INTERNATIONAL
- Dual inhibition of REV-ERBβ and autophagy as a novel pharmacological approach to induce cytotoxicity in cancer cells
- (2014) C De Mei et al. ONCOGENE
- Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer
- (2013) JOHANNA TUOMELA et al. Oncology Letters
- Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells
- (2012) Xian-ling Guo et al. CANCER LETTERS
- miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions
- (2012) Ying Chang et al. GASTROENTEROLOGY
- Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity
- (2012) Katelin N. Townsend et al. IMMUNOLOGICAL REVIEWS
- Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
- (2012) Q. McAfee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Active autophagy in the tumor microenvironment: A novel mechanism for cancer metastasis
- (2012) YINGHUA XU et al. Oncology Letters
- The Role of Autophagy in Cancer: Therapeutic Implications
- (2011) Z. J. Yang et al. MOLECULAR CANCER THERAPEUTICS
- Hydrocinchonine, cinchonine, and quinidine potentiate paclitaxel-induced cytotoxicity and apoptosis via multidrug resistance reversal in MES-SA/DX5 uterine sarcoma cells
- (2010) Sang-Yun Lee et al. ENVIRONMENTAL TOXICOLOGY
- Lucanthone Is a Novel Inhibitor of Autophagy That Induces Cathepsin D-mediated Apoptosis
- (2010) Jennifer S. Carew et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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