The relationship between autophagy and the immune system and its applications for tumor immunotherapy

IL4 (interleukin 4) induces autophagy in B cells leading to exacerbated asthma

(2018) Fucan Xia et al.   Autophagy

Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade

(2018) Sachet A. Shukla et al.   CELL

Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer

(2018) Wei Li et al.   Cell Metabolism

Blockade of Treg Cell Differentiation and Function by the Interleukin-21-Mechanistic Target of Rapamycin Axis Via Suppression of Autophagy in Patients With Systemic Lupus Erythematosus

(2018) Hiroshi Kato et al.   Arthritis & Rheumatology

Increased Interleukin-23 in Hashimoto’s Thyroiditis Disease Induces Autophagy Suppression and Reactive Oxygen Species Accumulation

(2018) Tingting Zheng et al.   Frontiers in Immunology

FAK and S6K1 Inhibitor, Neferine, Dually Induces Autophagy and Apoptosis in Human Neuroblastoma Cells

(2018) Dinh-Chuong Pham et al.   MOLECULES

Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway

(2018) Kim De Veirman et al.   CANCER LETTERS

Interleukin 6 protects pancreatic β cells from apoptosis by stimulation of autophagy

(2017) Amelia K. Linnemann et al.   FASEB JOURNAL

New Insights into the Role of Autophagy in Tumor Immune Microenvironment

(2017) Chia-Jung Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

(2017) Ainhoa Plaza-Zabala et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tregs restrain dendritic cell autophagy to ameliorate autoimmunity

(2017) Themis Alissafi et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion

(2017) Chao Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Reactive Oxygen Species-Mediated c-Jun NH 2 -Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction

(2017) Linmao Zhong et al.   JOURNAL OF VIROLOGY

Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis

(2017) Yi-Chia Lin et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Small-Molecule Sigma1 Modulator Induces Autophagic Degradation of PD-L1

(2017) Christina M. Maher et al.   MOLECULAR CANCER RESEARCH

TLR2 mediates autophagy through ERK signaling pathway in Mycoplasma gallisepticum -infected RAW264.7 cells

(2017) Ziyin Lu et al.   MOLECULAR IMMUNOLOGY

IL-12 induces autophagy in human breast cancer cells through AMPK and the PI3K/Akt pathway

(2017) Yan Lin et al.   Molecular Medicine Reports

Efficacy of an autophagy-targeted DNA vaccine against avian leukosis virus subgroup J

(2017) Zhenkai Dai et al.   VACCINE

Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy

(2017) Marianela Robainas et al.   OncoTargets and Therapy

IP3 Receptor-Mediated Calcium Signaling and Its Role in Autophagy in Cancer

(2017) Elzbieta Kania et al.   Frontiers in Oncology

Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

(2017) Kristine Pettersen et al.   Scientific Reports

Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment

(2016) Zhenyu Zhong et al.   CELL

High-mobility group box protein 1 promotes the survival of myeloid-derived suppressor cells by inducing autophagy

(2016) Katherine H. Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

(2016) Jun Wei et al.   NATURE IMMUNOLOGY

Autophagy: controlling cell fate in rheumatic diseases

(2016) Jason S. Rockel et al.   Nature Reviews Rheumatology

Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway

(2016) Xiang-Jun Fan et al.   ONCOLOGY REPORTS

Autophagy Beyond Intracellular MHC Class II Antigen Presentation

(2016) Christian Münz   TRENDS IN IMMUNOLOGY

IKKβ/NFκBp65 activated by interleukin-13 targets the autophagy-related genes LC3B and beclin 1 in fibroblasts co-cultured with breast cancer cells

(2016) WEN-LIN LI et al.   Experimental and Therapeutic Medicine

FoxO1-mediated autophagy is required for NK cell development and innate immunity

(2016) Shuo Wang et al.   Nature Communications

Autophagy-associated immune responses and cancer immunotherapy

(2016) Hongming Pan et al.   Oncotarget

IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma

(2016) Valentina Folgiero et al.   Oncotarget

Targeting CD73 in the tumor microenvironment with MEDI9447

(2016) Carl M. Hay et al.   OncoImmunology

Anti-CD73 immunotherapy: A viable way to reprogram the tumor microenvironment

(2016) Luca Antonioli et al.   OncoImmunology

Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47

(2016) Neeraj K. Saini et al.   Nature Microbiology

Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins

(2015) Katherine H. Schreiber et al.   AGING CELL

Integrating autophagy and metabolism in cancer

(2015) Heesun Cheong   ARCHIVES OF PHARMACAL RESEARCH

Autophagy of metallothioneins prevents TNF-induced oxidative stress and toxicity in hepatoma cells

(2015) Chiara Ullio et al.   Autophagy

Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells

(2015) Xuejiao Zhao et al.   Autophagy

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL

(2015) Soo-Ho Choi et al.   Autophagy

Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+T-cell activation

(2015) Yair Botbol et al.   Autophagy

Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1

(2015) Wei Jia et al.   Autophagy

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

(2015) Kun Liu et al.   Autophagy

Foxp3-dependent transformation of human primary CD4+ T lymphocytes by the retroviral protein tax

(2015) Li Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

VEGF inhibits the inflammation in spinal cord injury through activation of autophagy

(2015) Hongyu Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism

(2015) Ning Li et al.   CANCER BIOLOGY & THERAPY

Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses

(2015) J Arnold et al.   CELL DEATH AND DIFFERENTIATION

Autophagy and cell reprogramming

(2015) Shuo Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy, Metabolism, and Cancer

(2015) E. White et al.   CLINICAL CANCER RESEARCH

Macrophages enhance tumor-derived autophagosomes (DRibbles)-induced B cells activation by TLR4/MyD88 and CD40/CD40L

(2015) Meng Zhou et al.   EXPERIMENTAL CELL RESEARCH

TNF compromises lysosome acidification and reduces α-synuclein degradation via autophagy in dopaminergic cells

(2015) Mei-Xia Wang et al.   EXPERIMENTAL NEUROLOGY

Recent insights into cell death and autophagy

(2015) Brent E. Fitzwalter et al.   FEBS Journal

IL-10 restricts dendritic cell (DC) growth at the monocyte-to-monocyte-derived DC interface by disrupting anti-apoptotic and cytoprotective autophagic molecular machinery

(2015) Carla Martin et al.   IMMUNOLOGIC RESEARCH

The role of NOD1/CARD4 and NOD2/CARD15 genetic variations in lung cancer risk

(2015) Cansu Ozbayer et al.   INFLAMMATION RESEARCH

Celastrol ameliorates experimental colitis in IL-10 deficient mice via the up-regulation of autophagy

(2015) Jie Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1

(2015) Jiong Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy in DNA Damage Response

(2015) Piotr Czarny et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy Mediates HBx-Induced Nuclear Factor-κB Activation and Release of IL-6, IL-8, and CXCL2 in Hepatocytes

(2015) Millore X.M. Luo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells

(2015) Jichen Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma

(2015) Xue-Feng Li et al.   JOURNAL OF HEPATOLOGY

Invariant NKT Cells Require Autophagy To Coordinate Proliferation and Survival Signals during Differentiation

(2015) Bo Pei et al.   JOURNAL OF IMMUNOLOGY

Interleukin-10 inhibits chronic angiotensin II-induced pathological autophagy

(2015) Raj Kishore et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ryanodine Receptors: Allosteric Ion Channel Giants

(2015) Filip Van Petegem   JOURNAL OF MOLECULAR BIOLOGY

Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells

(2015) Elizabeth Liu et al.   MICROBES AND INFECTION

Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells

(2015) Myriam Catalano et al.   Molecular Oncology

Combination cancer immunotherapy and new immunomodulatory targets

(2015) Kathleen M. Mahoney et al.   NATURE REVIEWS DRUG DISCOVERY

Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation

(2015) Sho W. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy

(2015) Daniela Laura Papademetrio et al.   Targeted Oncology

The critical role of quercetin in autophagy and apoptosis in HeLa cells

(2015) Yijun Wang et al.   TUMOR BIOLOGY

IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes

(2015) Monica Gupta et al.   Nature Communications

Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells

(2015) Shu-Feng Zhou et al.   Drug Design Development and Therapy

IDO-GCN2 and autophagy in inflammation

(2015) Tracy L. McGaha   Oncotarget

IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway

(2015) Beibei Qin et al.   Scientific Reports

The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

(2015) Xue Yang et al.   Cell and Bioscience

Autophagy Is Required for Neutrophil-Mediated Inflammation

(2015) Abhisek Bhattacharya et al.   Cell Reports

Globular Adiponectin Causes Tolerance to LPS-Induced TNF-α Expression via Autophagy Induction in RAW 264.7 Macrophages: Involvement of SIRT1/FoxO3A Axis

(2015) Nirmala Tilija Pun et al.   PLoS One

Interleukin-1β Promotes Ovarian Tumorigenesis through a p53/NF-κB-Mediated Inflammatory Response in Stromal Fibroblasts

(2015) Isaiah Gregory Schauer et al.   NEOPLASIA

Autophagy-mediated regulation of macrophages and its applications for cancer

(2014) Peiwen Chen et al.   Autophagy

Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination

(2014) Zhenzhen Zhan et al.   Autophagy

IFNG-mediated immune responses enhance autophagy againstMycobacterium tuberculosisantigens in patients with active tuberculosis

(2014) Ana I Rovetta et al.   Autophagy

Autophagy in non-small cell lung carcinogenesis

(2014) Shuan Rao et al.   Autophagy

Autophagy: An adaptive metabolic response to stress shaping the antitumor immunity

(2014) Elodie Viry et al.   BIOCHEMICAL PHARMACOLOGY

Radiation-induced autophagy potentiates immunotherapy of cancer via up-regulation of mannose 6-phosphate receptor on tumor cells in mice

(2014) Sungjune Kim et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The generation of neutrophils in the bone marrow is controlled by autophagy

(2014) S Rožman et al.   CELL DEATH AND DIFFERENTIATION

The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense

(2014) Michiel van der Vaart et al.   Cell Host & Microbe

TLR2 mediates phagocytosis and autophagy through JNK signaling pathway in Staphylococcus aureus-stimulated RAW264.7 cells

(2014) Lei Fang et al.   CELLULAR SIGNALLING

Immunotherapy Targeting Folate Receptor Induces Cell Death Associated with Autophagy in Ovarian Cancer

(2014) Y. Wen et al.   CLINICAL CANCER RESEARCH

Adiponectin Suppresses Angiotensin II-Induced Inflammation and Cardiac Fibrosis through Activation of Macrophage Autophagy

(2014) Guan-Ming Qi et al.   ENDOCRINOLOGY

Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma

(2014) Ke Gong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Autophagy in T-cell development, activation and differentiation

(2014) Alisha W Bronietzki et al.   IMMUNOLOGY AND CELL BIOLOGY

IL-27 inhibits IFN-γ induced autophagy by concomitant induction of JAK/PI3 K/Akt/mTOR cascade and up-regulation of Mcl-1 in Mycobacterium tuberculosis H37Rv infected macrophages

(2014) Gaurav Sharma et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Autophagy: Detection, regulation and its role in cancer and therapy response

(2014) Pia Hönscheid et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Feasibility Analysis of p62 (SQSTM1)—Encoding DNA Vaccine as a Novel Cancer Immunotherapy

(2014) Vladimir L. Gabai et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Gene of the month:BECN1

(2014) Sumit Sahni et al.   JOURNAL OF CLINICAL PATHOLOGY

Cutting Edge: Generation of Effector Cells That Localize to Mucosal Tissues and Form Resident Memory CD8 T Cells Is Controlled by mTOR

(2014) Ryan T. Sowell et al.   JOURNAL OF IMMUNOLOGY

New Function of Type I IFN: Induction of Autophagy

(2014) Hana Schmeisser et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Autophagy Regulates TGF-  Expression and Suppresses Kidney Fibrosis Induced by Unilateral Ureteral Obstruction

(2014) Y. Ding et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers

(2014) Saurabh V. Laddha et al.   MOLECULAR CANCER RESEARCH

Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins

(2014) Yongxing Gong et al.   NATURE GENETICS

Autophagy is essential for effector CD8+ T cell survival and memory formation

(2014) Xiaojin Xu et al.   NATURE IMMUNOLOGY

Targeting RAS–ERK signalling in cancer: promises and challenges

(2014) Ahmed A. Samatar et al.   NATURE REVIEWS DRUG DISCOVERY

Rotundarpene prevents TRAIL-induced apoptosis in human keratinocytes by suppressing the caspase-8- and Bid-pathways and the mitochondrial pathway

(2014) Da Hee Lee et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Regulation of Nasal Airway Homeostasis and Inflammation in Mice by SHP-1 and Th2/Th1 Signaling Pathways

(2014) Seok Hyun Cho et al.   PLoS One

Essential role for autophagy during invariant NKT cell development

(2014) Mariolina Salio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Honokiol activates reactive oxygen species-mediated cytoprotective autophagy in human prostate cancer cells

(2014) Eun-Ryeong Hahm et al.   PROSTATE

A dual role for autophagy in a murine model of lung cancer

(2014) Shuan Rao et al.   Nature Communications

Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations

(2014) A. Yang et al.   Cancer Discovery

STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells

(2014) Roberta Santarelli et al.   Scientific Reports

Antagonism of Tumoral Prolactin Receptor Promotes Autophagy-Related Cell Death

(2014) Yunfei Wen et al.   Cell Reports

Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy

(2013) Asako Itakura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Caspase-1 Activation is Increased with Human Labour in Foetal Membranes and Myometrium and Mediates Infection-Induced Interleukin-1β Secretion

(2013) Martha Lappas   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The dual mTORC1 and mTORC2 inhibitor AZD8055 inhibits head and neck squamous cell carcinoma cell growth in vivo and in vitro

(2013) Qiang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy-Mediated Tumor Promotion

(2013) Jessie Yanxiang Guo et al.   CELL

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

Intracellular calcium channels: Inositol-1,4,5-trisphosphate receptors

(2013) Olena A. Fedorenko et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

The Protein ATG16L1 Suppresses Inflammatory Cytokines Induced by the Intracellular Sensors Nod1 and Nod2 in an Autophagy-Independent Manner

(2013) Matthew T. Sorbara et al.   IMMUNITY

The expanding role of NLRs in antiviral immunity

(2013) Christopher Lupfer et al.   IMMUNOLOGICAL REVIEWS

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

(2013) Mayur V. Jain et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Impaired Autophagy, Defective T Cell Homeostasis, and a Wasting Syndrome in Mice with a T Cell-Specific Deletion of Vps34

(2013) V. V. Parekh et al.   JOURNAL OF IMMUNOLOGY

Nod1 and Nod2 Enhance TLR-Mediated Invariant NKT Cell Activation during Bacterial Infection

(2013) T. Selvanantham et al.   JOURNAL OF IMMUNOLOGY

Secretory versus Degradative Autophagy: Unconventional Secretion of Inflammatory Mediators

(2013) Shanya Jiang et al.   Journal of Innate Immunity

Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer

(2013) Yuan-yuan Li et al.   LUNG CANCER

FOXO3A directs a protective autophagy program in haematopoietic stem cells

(2013) Matthew R. Warr et al.   NATURE

p53 status determines the role of autophagy in pancreatic tumour development

(2013) Mathias T. Rosenfeldt et al.   NATURE

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function

(2013) Hu Zeng et al.   NATURE

RNA-Dependent Protein Kinase Is Essential for 2-Methoxyestradiol-Induced Autophagy in Osteosarcoma Cells

(2013) Caihong Yang et al.   PLoS One

Autophagy Adaptor Protein p62/SQSTM1 and Autophagy-Related Gene Atg5 Mediate Autophagosome Formation in Response to Mycobacterium tuberculosis Infection in Dendritic Cells

(2013) Shintaro Seto et al.   PLoS One

The Interplay between NLRs and Autophagy in Immunity and Inflammation

(2013) Leticia A. M. Carneiro et al.   Frontiers in Immunology

Autophagy-dependent suppression of cancer immunogenicity and effector mechanisms of innate and adaptive immunity

(2013) Abhishek D Garg et al.   OncoImmunology

Autophagy as an Innate Immune Modulator

(2013) Ji Eun Oh et al.   Immune Network

Hypoxia-induced autophagy

(2012) Muhammad Zaeem Noman et al.   Autophagy

DEDD, a novel tumor repressor, reverses epithelial-mesenchymal transition by activating selective autophagy

(2012) Qi Lv et al.   Autophagy

Proper macrophagic differentiation requires both autophagy and caspase activation

(2012) Arnaud Jacquel et al.   Autophagy

Blocking the interleukin 2 (IL2)-induced systemic autophagic syndrome promotes profound antitumor effects and limits toxicity

(2012) Michael T. Lotze et al.   Autophagy

α-TEA as a stimulator of tumor autophagy and enhancer of antigen cross-presentation

(2012) Tobias Hahn et al.   Autophagy

Induction of autophagy is essential for monocyte-macrophage differentiation

(2012) Y. Zhang et al.   BLOOD

Inhibiting Systemic Autophagy during Interleukin 2 Immunotherapy Promotes Long-term Tumor Regression

(2012) X. Liang et al.   CANCER RESEARCH

Cell-Mediated Autophagy Promotes Cancer Cell Survival

(2012) W. J. Buchser et al.   CANCER RESEARCH

The Vitamin E Analogue  -TEA Stimulates Tumor Autophagy and Enhances Antigen Cross-Presentation

(2012) Y. Li et al.   CANCER RESEARCH

Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy

(2012) R. Ramakrishnan et al.   CANCER RESEARCH

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Autophagy is required for IL-2-mediated fibroblast growth

(2012) Rui Kang et al.   EXPERIMENTAL CELL RESEARCH

Amino acid catabolism: a pivotal regulator of innate and adaptive immunity

(2012) Tracy L. McGaha et al.   IMMUNOLOGICAL REVIEWS

IL-6 inhibits IFN-γ induced autophagy in Mycobacterium tuberculosis H37Rv infected macrophages

(2012) Rajesh Kumar Dutta et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

HTLV-2 Tax Immortalizes Human CD4+Memory T Lymphocytes by Oncogenic Activation and Dysregulation of Autophagy

(2012) Tong Ren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFN-  Elicits Macrophage Autophagy via the p38 MAPK Signaling Pathway

(2012) T. Matsuzawa et al.   JOURNAL OF IMMUNOLOGY

Autophagy Regulates IL-23 Secretion and Innate T Cell Responses through Effects on IL-1 Secretion

(2012) C. Peral de Castro et al.   JOURNAL OF IMMUNOLOGY

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics

(2012) L Y Dimberg et al.   ONCOGENE

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

(2012) E. F. Castillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p62: a versatile multitasker takes on cancer

(2012) Jorge Moscat et al.   TRENDS IN BIOCHEMICAL SCIENCES

Autophagy in the regulation of pathogen replication and adaptive immunity

(2012) Felix Randow et al.   TRENDS IN IMMUNOLOGY

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

(2012) Richard Metz et al.   OncoImmunology

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

IFN-  Inhibits Gastric Carcinogenesis by Inducing Epithelial Cell Autophagy and T-Cell Apoptosis

(2011) S. P. Tu et al.   CANCER RESEARCH

Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery

(2011) J R Kovacs et al.   CELL DEATH AND DIFFERENTIATION

Tumor-Derived Autophagosome Vaccine: Induction of Cross-Protective Immune Responses against Short-lived Proteins through a p62-Dependent Mechanism

(2011) C. G. Twitty et al.   CLINICAL CANCER RESEARCH

Autophagy and cytokines

(2011) James Harris   CYTOKINE

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

(2011) R. D. Michalek et al.   JOURNAL OF IMMUNOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

T Cells from Programmed Death-1 Deficient Mice Respond Poorly to Mycobacterium tuberculosis Infection

(2011) Sultan Tousif et al.   PLoS One

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

(2011) Erica B. Wilson et al.   PLoS One

Regulation of autophagy by transforming growth factor-β (TGF-β) signaling

(2010) Hiroshi I. Suzuki et al.   Autophagy

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Lactic acid bacteria enhance autophagic ability of mononuclear phagocytes by increasing Th1 autophagy-promoting cytokine (IFN-γ) and nitric oxide (NO) levels and reducing Th2 autophagy-restraining cytokines (IL-4 and IL-13) in response to Mycobacterium tuberculosis antigen

(2010) Darab Ghadimi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Macroautophagy Regulates Energy Metabolism during Effector T Cell Activation

(2010) V. M. Hubbard et al.   JOURNAL OF IMMUNOLOGY

IL-10 inhibits the starvation induced autophagy in macrophages via class I phosphatidylinositol 3-kinase (PI3K) pathway

(2010) Hun-Jung Park et al.   MOLECULAR IMMUNOLOGY

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes

(2009) H. H. Pua et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Differential requirement of PKC-θ in the development and function of natural regulatory T cells

(2008) Sonal Gupta et al.   MOLECULAR IMMUNOLOGY