Three-dimensional mitochondria reconstructions of murine cardiac muscle changes in size across aging

A Comprehensive Approach to Sample Preparation for Electron Microscopy and the Assessment of Mitochondrial Morphology in Tissue and Cultured Cells

(2023) Antentor Hinton et al.   Advanced Biology

Disruption of the MICOS complex leads to an aberrant cristae structure and an unexpected, pronounced lifespan extension in Podospora anserina

(2022) Verena Warnsmann et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits

(2022) Gita A. Pathak et al.   MOLECULAR PSYCHIATRY

Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome

(2022) Jin‐Young Yoon et al.   Clinical and Translational Medicine

Isolation and culture of adult murine cardiac atrial and ventricular fibroblasts and myofibroblasts

(2021) Pramod Sahadevan et al.   METHODS

FIB-SEM as a Volume Electron Microscopy Approach to Study Cellular Architectures in SARS-CoV-2 and Other Viral Infections: A Practical Primer for a Virologist

(2021) Valentina Baena et al.   Viruses-Basel

OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21

(2021) Renata O Pereira et al.   eLife

Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

(2021) Rubén Quintana-Cabrera et al.   Redox Biology

Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility

(2021) Jingwen Zhang et al.   AGING CELL

A Universal Approach to Analyzing Transmission Electron Microscopy with ImageJ

(2021) Jacob Lam et al.   Cells

Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice

(2021) Jil Messerer et al.   JOURNAL OF ANATOMY

Protocols for Generating Surfaces and Measuring 3D Organelle Morphology Using Amira

(2021) Edgar Garza-Lopez et al.   Cells

Subcellular Specialization of Mitochondrial Form and Function in Skeletal Muscle Cells

(2021) T. Bradley Willingham et al.   Frontiers in Cell and Developmental Biology

Cristae undergo continuous cycles of membrane remodelling in a MICOS ‐dependent manner

(2020) Arun Kumar Kondadi et al.   EMBO REPORTS

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation

(2020) Till Stephan et al.   EMBO JOURNAL

NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

(2020) Erica R. Gansemer et al.   iScience

ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

(2020) Jinshan Qin et al.   Nature Communications

Drosophila MICOS knockdown impairs mitochondrial structure and function and promotes mitophagy in muscle tissue

(2020) Li-jie Wang et al.   Biology Open

Heart Failure in Type 2 Diabetes Mellitus

(2019) Helena C. Kenny et al.   CIRCULATION RESEARCH

Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network

(2019) Amy E. Vincent et al.   Cell Reports

Functional Interplay between Cristae Biogenesis, Mitochondrial Dynamics and Mitochondrial DNA Integrity

(2019) Arun Kumar Kondadi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The ‘mitochondrial contact site and cristae organising system’ (MICOS) in health and human disease

(2019) Matthew J Eramo et al.   JOURNAL OF BIOCHEMISTRY

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses

(2018) Verónica Eisner et al.   NATURE CELL BIOLOGY

Mitochondria with Morphology Characteristic for Alzheimer’s Disease Patients Are Found in the Brain of OXYS Rats

(2018) M. A. Tyumentsev et al.   BIOCHEMISTRY-MOSCOW

Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse

(2018) Cathleen John et al.   Frontiers in Endocrinology

Increased mitochondrial nanotunneling activity, induced by calcium imbalance, affects intermitochondrial matrix exchanges

(2017) Manuela Lavorato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Nanotunnels

(2017) Amy E. Vincent et al.   TRENDS IN CELL BIOLOGY

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission

(2017) Kensuke Tsushima et al.   CIRCULATION RESEARCH

The MICOS complex of human mitochondria

(2016) Vera Kozjak-Pavlovic   CELL AND TISSUE RESEARCH

Mitochondrial Metabolism in Aging Heart

(2016) Edward J. Lesnefsky et al.   CIRCULATION RESEARCH

OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation

(2016) Miguel Barrera et al.   FEBS LETTERS

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

(2016) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Gender difference in oxidative stress: a new look at the mechanisms for cardiovascular diseases

(2016) Melissa Christine Kander et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mitochondrial function as a therapeutic target in heart failure

(2016) David A. Brown et al.   Nature Reviews Cardiology

SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice

(2016) Antentor Othrell Hinton et al.   PLoS One

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control

(2016) Christina Glytsou et al.   Cell Reports

Dynamic tubulation of mitochondria drives mitochondrial network formation

(2015) Chong Wang et al.   CELL RESEARCH

Mitochondrial reticulum for cellular energy distribution in muscle

(2015) Brian Glancy et al.   NATURE

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage

(2014) Wei Zuo et al.   NEUROPHARMACOLOGY

Deregulation of Mitochondria-Shaping Proteins Opa-1 and Drp-1 in Manganese-Induced Apoptosis

(2014) Agustina Alaimo et al.   PLoS One

Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF B-Opa-1 Signaling Pathway

(2013) V. Parra et al.   DIABETES

Computational classification of mitochondrial shapes reflects stress and redox state

(2013) T Ahmad et al.   Cell Death & Disease

Methods for Detection of Mitochondrial and Cellular Reactive Oxygen Species

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial morphology, topology, and membrane interactions in skeletal muscle: a quantitative three-dimensional electron microscopy study

(2012) Martin Picard et al.   JOURNAL OF APPLIED PHYSIOLOGY

Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress

(2012) Gladys A. Ngoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria as a Therapeutic Target in Heart Failure

(2012) Marina Bayeva et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

(2011) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria and the aging heart

(2011) Chaudhary Ketul R et al.   Journal of Geriatric Cardiology

The role of mitochondria in aging of skeletal muscle

(2008) Pedro Alexandre Figueiredo et al.   BIOGERONTOLOGY

Role of Mitochondrial Dysfunction in Insulin Resistance

(2008) Jeong-a Kim et al.   CIRCULATION RESEARCH