Synthetic torpor triggers a regulated mechanism in the rat brain, favoring the reversibility of Tau protein hyperphosphorylation

Reversible Tau Phosphorylation Induced by Synthetic Torpor in the Spinal Cord of the Rat

(2021) Timna Hitrec et al.   Frontiers in Neuroanatomy

Be cool to be far: Exploiting hibernation for space exploration

(2021) Matteo Cerri et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Cellular senescence at the crossroads of inflammation and Alzheimer's disease

(2021) Ana Guerrero et al.   TRENDS IN NEUROSCIENCES

Necroptosis: A Novel Pathway in Neuroinflammation

(2021) Ziyu Yu et al.   Frontiers in Pharmacology

Synergy between amyloid-β and tau in Alzheimer’s disease

(2020) Marc Aurel Busche et al.   NATURE NEUROSCIENCE

Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model

(2020) Juan Jose Fernandez-Valenzuela et al.   Scientific Reports

Hibernation and Radioprotection: Gene Expression in the Liver and Testicle of Rats Irradiated under Synthetic Torpor

(2019) Walter Tinganelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GRP78: A cell's response to stress

(2019) Ibrahim M. Ibrahim et al.   LIFE SCIENCES

Phosphorylation and Dephosphorylation of Tau Protein During Synthetic Torpor

(2019) Marco Luppi et al.   Frontiers in Neuroanatomy

The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease

(2019) Alessandra Webers et al.   IMMUNOLOGY AND CELL BIOLOGY

Neural control of fasting-induced torpor in mice

(2019) Timna Hitrec et al.   Scientific Reports

Melatonin Target Proteins: Too Many or Not Enough?

(2019) Lei Liu et al.   Frontiers in Endocrinology

Brain inflammatory cytokines and microglia morphology changes throughout hibernation phases in Syrian hamster

(2018) V. Cogut et al.   BRAIN BEHAVIOR AND IMMUNITY

The influence of sex and neonatal stress on medullary microglia in rat pups

(2018) Cécile Baldy et al.   EXPERIMENTAL PHYSIOLOGY

Melatonin ameliorates Aβ42 -induced alteration of βAPP-processing secretases via the melatonin receptor through the Pin1/GSK3β/NF-κB pathway in SH-SY5Y cells

(2018) Vorapin Chinchalongporn et al.   JOURNAL OF PINEAL RESEARCH

Neuronal Cell Death

(2018) Michael Fricker et al.   PHYSIOLOGICAL REVIEWS

Central Mechanisms for Thermoregulation

(2018) S.F. Morrison et al.   Annual Review of Physiology

Different Patterns of Neurodegeneration and Glia Activation in CA1 and CA3 Hippocampal Regions of TgCRND8 Mice

(2018) Filippo Ugolini et al.   Frontiers in Aging Neuroscience

Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives

(2018) Urszula Majcher et al.   Cells

Anti-aggregant tau mutant promotes neurogenesis

(2017) Maria Joseph et al.   Molecular Neurodegeneration

AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity

(2017) Josien Levenga et al.   eLife

Characterizing microglia activation: a spatial statistics approach to maximize information extraction

(2017) Benjamin M. Davis et al.   Scientific Reports

Potential mechanisms and implications for the formation of tau oligomeric strains

(2016) Julia E. Gerson et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases

(2016) Ashley N. Nilson et al.   JOURNAL OF ALZHEIMERS DISEASE

Recent Advances in Neurogenic Small Molecules as Innovative Treatments for Neurodegenerative Diseases

(2016) Clara Herrera-Arozamena et al.   MOLECULES

Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8

(2016) Thomas J. Malia et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice

(2016) Arne Ittner et al.   SCIENCE

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

Akt/PKB: one kinase, many modifications

(2015) Guillermo Risso et al.   BIOCHEMICAL JOURNAL

Anatomical and cellular localization of melatonin MT1and MT2receptors in the adult rat brain

(2015) Baptiste Lacoste et al.   JOURNAL OF PINEAL RESEARCH

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

The MT2 receptor stimulates axonogenesis and enhances synaptic transmission by activating Akt signaling

(2014) D Liu et al.   CELL DEATH AND DIFFERENTIATION

Hormones and hibernation: possible links between hormone systems, winter energy balance and white-nose syndrome in bats

(2014) Craig K.R. Willis et al.   HORMONES AND BEHAVIOR

Brain hypometabolism triggers PHF-like phosphorylation of tau, a major hallmark of Alzheimer’s disease pathology

(2014) Thomas Arendt et al.   JOURNAL OF NEURAL TRANSMISSION

The Inhibition of Neurons in the Central Nervous Pathways for Thermoregulatory Cold Defense Induces a Suspended Animation State in the Rat

(2013) M. Cerri et al.   JOURNAL OF NEUROSCIENCE

Anesthesia and tau pathology

(2013) Robert A. Whittington et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease

(2012) Travis J. A. Craddock et al.   PLoS One

Caspase-3 activation as a bifurcation point between plasticity and cell death

(2012) Shikha Snigdha et al.   Neuroscience Bulletin

Torpor patterns, arousal rates, and temporal organization of torpor entry in wildtype and UCP1-ablated mice

(2010) R. Oelkrug et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Torpor and ultradian rhythms require an intact signalling of the sympathetic nervous system

(2009) Luzie J. Braulke et al.   CRYOBIOLOGY

Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia

(2009) Emmanuel Planel et al.   FASEB JOURNAL

Physiological regulation of tau phosphorylation during hibernation

(2008) Bo Su et al.   JOURNAL OF NEUROCHEMISTRY