标题
The G protein-coupled oestrogen receptor GPER in health and disease: an update
作者
关键词
-
出版物
Nature Reviews Endocrinology
Volume 19, Issue 7, Pages 407-424
出版商
Springer Science and Business Media LLC
发表日期
2023-05-16
DOI
10.1038/s41574-023-00822-7
参考文献
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- Estrogen induces two distinct cholesterol crystallization pathways by activating ERα and GPR30 in female mice
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- Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1
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- GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner
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- The effects of (−)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER)
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- G-Protein-Coupled Estrogen Receptor Agonist Suppresses Airway Inflammation in a Mouse Model of Asthma through IL-10
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- The G Protein-coupled Estrogen Receptor (GPER) Agonist G-1 Expands the Regulatory T-cell Population Under TH17-polarizing Conditions
- (2013) Ryan L. Brunsing et al. JOURNAL OF IMMUNOTHERAPY
- The Women's Health Initiative trial and related studies: 10 years later: A clinician's view
- (2013) Elizabeth P. Gurney et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Anatomical location and redistribution of G protein-coupled estrogen receptor-1 during the estrus cycle in mouse kidney and specific binding to estrogens but not aldosterone
- (2013) Shi-Bin Cheng et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells
- (2013) Adele Chimento et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation
- (2013) Fen Li et al. PLoS One
- Regulation of Vascular Smooth Muscle Tone by Adipose-Derived Contracting Factor
- (2013) Matthias R. Meyer et al. PLoS One
- Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling
- (2013) Sarah H. Lindsey et al. STEROIDS
- G Protein–Coupled Estrogen Receptor Agonist Improves Cerebral Microvascular Function After Hypoxia/Reoxygenation Injury in Male and Female Rats
- (2013) Takahiro Murata et al. STROKE
- 4-Hydroxytamoxifen-stimulated processing of cyclin E is mediated via G protein-coupled receptor 30 (GPR30) and accompanied by enhanced migration in MCF-7 breast cancer cells
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- Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodelling in oophorectomized mRen2.Lewis rats
- (2012) Hao Wang et al. CARDIOVASCULAR RESEARCH
- Two Novel GPER Agonists Induce Gene Expression Changes and Growth Effects in Cancer Cells
- (2012) R. Lappano et al. CURRENT CANCER DRUG TARGETS
- GPER regulates endothelin-dependent vascular tone and intracellular calcium
- (2012) Matthias R. Meyer et al. LIFE SCIENCES
- The DHEA metabolite 7β-hydroxy-epiandrosterone exerts anti-estrogenic effects on breast cancer cell lines
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- Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors
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- Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle
- (2011) Xuan Yu et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Estrogen Rescues Preexisting Severe Pulmonary Hypertension in Rats
- (2011) Soban Umar et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- A Conversation with Elwood Jensen
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- G-protein-coupled estrogen receptor GPR30 and tamoxifen resistance in breast cancer
- (2011) Atanas Ignatov et al. BREAST CANCER RESEARCH AND TREATMENT
- Insulinotropic and Antidiabetic Effects of 17β-Estradiol and the GPR30 Agonist G-1 on Human Pancreatic Islets
- (2011) Rajesh Kumar et al. ENDOCRINOLOGY
- Mechanisms of Estradiol-Induced Insulin Secretion by the G Protein-Coupled Estrogen Receptor GPR30/GPER in Pancreatic β-Cells
- (2011) Geetanjali Sharma et al. ENDOCRINOLOGY
- Estrogen modulates abdominal adiposity and protects female mice from obesity and impaired glucose tolerance
- (2011) Renee E. Stubbins et al. EUROPEAN JOURNAL OF NUTRITION
- Estrogen Receptor GPR30 Reduces Oxidative Stress and Proteinuria in the Salt-Sensitive Female mRen2.Lewis Rat
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- Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1
- (2011) Ryan L. Brunsing et al. IMMUNOLOGY
- The G Protein-coupled Receptor 30 Is Up-regulated by Hypoxia-inducible Factor-1α (HIF-1α) in Breast Cancer Cells and Cardiomyocytes
- (2011) Anna Grazia Recchia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity
- (2011) Megan K. Dennis et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Contribution of GPR30 for 1,25 dihydroxyvitamin D3 protection in EAE
- (2011) Sandhya Subramanian et al. METABOLIC BRAIN DISEASE
- The G-protein-coupled estrogen receptor GPER in health and disease
- (2011) Eric R. Prossnitz et al. Nature Reviews Endocrinology
- Differential vasoactive effects of oestrogen, oestrogen receptor agonists and selective oestrogen receptor modulators in rat middle cerebral artery
- (2011) S. Patkar et al. NEUROSCIENCE RESEARCH
- Expression and Signaling of G Protein-Coupled Estrogen Receptor 1 (GPER) in Rat Sertoli Cells1
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- Nuclear Alternate Estrogen Receptor GPR30 Mediates 17 -Estradiol-Induced Gene Expression and Migration in Breast Cancer-Associated Fibroblasts
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- The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells
- (2010) E. A. Ariazi et al. CANCER RESEARCH
- Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21 and induction of G2 cell-cycle arrest
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- Hormonal Action of Plant Derived and Anthropogenic Non-Steroidal Estrogenic Compounds: Phytoestrogens and Xenoestrogens
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- Estradiol and G1 Reduce Infarct Size and Improve Immunosuppression after Experimental Stroke
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- GPR30/GPER-1 mediates rapid decreases in TLR4 expression on murine macrophages
- (2010) Jennifer A. Rettew et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice
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- Dilation of Epicardial Coronary Arteries by the G Protein-Coupled Estrogen Receptor Agonists G-1 and ICI 182,780
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- Attenuation of Salt-Induced Cardiac Remodeling and Diastolic Dysfunction by the GPER Agonist G-1 in Female mRen2.Lewis Rats
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- A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury
- (2009) Jean Chrisostome Bopassa et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation
- (2009) Helen H. Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells
- (2009) Atanas Ignatov et al. BREAST CANCER RESEARCH AND TREATMENT
- Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity
- (2009) Elvira Haas et al. CIRCULATION RESEARCH
- Importance of Extranuclear Estrogen Receptor- and Membrane G Protein-Coupled Estrogen Receptor in Pancreatic Islet Survival
- (2009) S. Liu et al. DIABETES
- Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
- (2009) Deo Prakash Pandey et al. EMBO JOURNAL
- Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
- (2009) Evanthia Diamanti-Kandarakis et al. ENDOCRINE REVIEWS
- GPR30 predicts poor survival for ovarian cancer
- (2009) Harriet O. Smith et al. GYNECOLOGIC ONCOLOGY
- Membrane Estrogen Receptor Regulates Experimental Autoimmune Encephalomyelitis through Up-regulation of Programmed Death 1
- (2009) C. Wang et al. JOURNAL OF IMMUNOLOGY
- Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis
- (2009) Eric Blasko et al. JOURNAL OF NEUROIMMUNOLOGY
- In vivo effects of a GPR30 antagonist
- (2009) Megan K Dennis et al. Nature Chemical Biology
- 2-methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats
- (2009) Stevan P. Tofovic et al. VASCULAR PHARMACOLOGY
- Guide to Receptors and Channels (GRAC), 3rd edition
- (2008) S P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Deletion of the G Protein-Coupled Receptor 30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-Stimulated Insulin Release in Female Mice
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