Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1

GPR30, but not estrogen receptor-α, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol

(2010) Melissa A Yates et al.   BMC IMMUNOLOGY

T helper 17 cells: discovery, function, and physiological trigger

(2010) Miriam Beer Torchinsky et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interleukin-17: friend or foe in atherosclerosis?

(2010) Soraya Taleb et al.   CURRENT OPINION IN LIPIDOLOGY

Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3+ regulatory T cells implicates compensatory pathways including regulatory B cells

(2010) Sandhya Subramanian et al.   IMMUNOLOGY

B cell depletion reduces the development of atherosclerosis in mice

(2010) Hafid Ait-Oufella et al.   JOURNAL OF EXPERIMENTAL MEDICINE

1,25-dihydroxyvitamin D3modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis

(2009) E. M. Colin et al.   ARTHRITIS AND RHEUMATISM

IL-17-producing human peripheral regulatory T cells retain suppressive function

(2009) G. Beriou et al.   BLOOD

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes

(2009) M. D. Sharma et al.   BLOOD

Developmental plasticity of Th17 and Treg cells

(2009) Yun Kyung Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Interleukin-10 Production by Th1 Cells Requires Interleukin-12-Induced STAT4 Transcription Factor and ERK MAP Kinase Activation by High Antigen Dose

(2009) Margarida Saraiva et al.   IMMUNITY

Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation

(2009) Craig L. Maynard et al.   IMMUNOLOGICAL REVIEWS

Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation

(2009) Jyoti Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

(2009) Soraya Taleb et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Membrane Estrogen Receptor Regulates Experimental Autoimmune Encephalomyelitis through Up-regulation of Programmed Death 1

(2009) C. Wang et al.   JOURNAL OF IMMUNOLOGY

IL-21 Mediates Suppressive Effects via Its Induction of IL-10

(2009) R. Spolski et al.   JOURNAL OF IMMUNOLOGY

Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis

(2009) Eric Blasko et al.   JOURNAL OF NEUROIMMUNOLOGY

In vivo effects of a GPR30 antagonist

(2009) Megan K Dennis et al.   Nature Chemical Biology

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

Hybrid Treg cells: steel frames and plastic exteriors

(2009) Michael J Barnes et al.   NATURE IMMUNOLOGY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30

(2008) Eric R. Prossnitz et al.   Annual Review of Physiology

Tumor-specific Th17-polarized cells eradicate large established melanoma

(2008) P. Muranski et al.   BLOOD

Strategies for use of IL-10 or its antagonists in human disease

(2008) Anne O'Garra et al.   IMMUNOLOGICAL REVIEWS

Digestive histopathological presentation of IPEX syndrome

(2008) Natacha Patey-Mariaud de Serre et al.   MODERN PATHOLOGY

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

GPR30 Contributes to Estrogen-Induced Thymic Atrophy

(2007) Chunhe Wang et al.   MOLECULAR ENDOCRINOLOGY