标题
Tryptophan metabolism in health and disease
作者
关键词
-
出版物
Cell Metabolism
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2023-06-23
DOI
10.1016/j.cmet.2023.06.004
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effects of 3‐HAA on HCC by Regulating the Heterogeneous Macrophages—A scRNA‐Seq Analysis
- (2023) Chen Xue et al. Advanced Science
- Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
- (2022) Kebria Hezaveh et al. IMMUNITY
- Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses
- (2022) Kunle Odunsi et al. Science Translational Medicine
- Cancer-associated fibroblasts strengthen cell proliferation and EGFR TKIs resistance through aryl hydrocarbon receptor dependent signals in non-small cell lung cancer
- (2022) Hao Feng et al. BMC CANCER
- Tryptophan-rich diet ameliorates chronic unpredictable mild stress induced depression- and anxiety-like behavior in mice: The potential involvement of gut-brain axis
- (2022) Danna Wang et al. FOOD RESEARCH INTERNATIONAL
- The Role of Tryptophan Dysmetabolism and Quinolinic Acid in Depressive and Neurodegenerative Diseases
- (2022) Knut Hestad et al. Biomolecules
- Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases
- (2022) Chloé Michaudel et al. GUT
- USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer
- (2022) Dongni Shi et al. Nature Communications
- Tryptophan-5-HT pathway disorder was uncovered in the olfactory bulb of a depression mice model by metabolomic analysis
- (2022) Guanghui Chen et al. Frontiers in Molecular Neuroscience
- Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease
- (2021) Luke Whiley et al. Alzheimers Research & Therapy
- TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway
- (2021) Lei Li et al. Frontiers in Oncology
- Serotonin Pathway in Cancer
- (2021) Pragathi Balakrishna et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inflammation, Negative Affect, and Amyloid Burden in Alzheimer’s Disease: Insights from the Kynurenine Pathway
- (2021) Auriel A. Willette et al. BRAIN BEHAVIOR AND IMMUNITY
- Enteric Microbiota-Mediated Serotonergic Signaling in Pathogenesis of Irritable Bowel Syndrome
- (2021) Yoshiyuki Mishima et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor
- (2021) George Zhang Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDO2 Was Downregulated in Hepatocellular Carcinoma and Inhibited Cell Proliferation by Upregulating the Expression of p21 and p27
- (2021) Chengpeng Yu et al. Biomed Research International
- Constitutive TDO2 expression promotes liver cancer progression by an autocrine IL-6 signaling pathway
- (2021) Zhengzhong Wu et al. Cancer Cell International
- Kynurenine derivative 3-HAA is an agonist ligand for transcription factor YY1
- (2021) Zhaopeng Shi et al. Journal of Hematology & Oncology
- Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice
- (2020) Rooban B. Nahomi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- IDO, TDO, and AHR overexpression is associated with poor outcome in diffuse large B-cell lymphoma patients in the rituximab era
- (2020) Xiangli Chen et al. MEDICINE
- Kynurenine pathway enzyme KMO in cancer progression: A tip of the Iceberg
- (2020) So-Yeon Park et al. EBioMedicine
- Tryptophan Metabolism, Inflammation, and Oxidative Stress in Patients with Neurovascular Disease
- (2020) Martin Hajsl et al. Metabolites
- Immunohistochemical Features of Indoleamine 2,3-Dioxygenase (IDO) in Various Types of Lymphoma: A Single Center Experience
- (2020) Mee-seon Kim et al. Diagnostics
- Comprehensive assessment of multiple tryptophan metabolites as potential biomarkers for immune checkpoint inhibitors in patients with non-small cell lung cancer
- (2020) M. Karayama et al. Clinical & Translational Oncology
- Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma
- (2020) Erik Ladomersky et al. CLINICAL CANCER RESEARCH
- Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
- (2020) Patrick L. Heilman et al. MOVEMENT DISORDERS
- Antiproliferative Effects of Telotristat Ethyl in Patients with Neuroendocrine Tumors: The TELEACE Real-World Chart Review Study
- (2020) Michael A Morse et al. Cancer Management and Research
- IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
- (2020) Ahmed Sadik et al. CELL
- Clinical significance of tryptophan catabolism in follicular lymphoma
- (2020) Ayako Masaki et al. HEMATOLOGICAL ONCOLOGY
- Bacteroides thetaiotaomicron relieves colon inflammation by activating aryl hydrocarbon receptor and modulating CD4+T cell homeostasis
- (2020) Keying Li et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies
- (2020) Wolfgang Marx et al. MOLECULAR PSYCHIATRY
- Tryptophan Metabolism as a Pharmacological Target
- (2020) Morgane Modoux et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- N-(6-phenylpyridazin-3-yl)benzenesulfonamides as highly potent, brain-permeable, and orally active kynurenine monooxygenase inhibitors
- (2020) Hidenori Kimura et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
- (2019) Nils Eiel Steen et al. PSYCHOLOGICAL MEDICINE
- Increasing carbohydrate availability in the hindgut promotes hypothalamic neurotransmitter synthesis: aromatic amino acids linking the microbiota–brain axis
- (2019) Kan Gao et al. JOURNAL OF NEUROCHEMISTRY
- Non-NF2 mutations have a key effect on inhibitory immune checkpoints and tumor pathogenesis in skull base meningiomas
- (2019) Shuyu Hao et al. JOURNAL OF NEURO-ONCOLOGY
- MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer
- (2019) Niranjan Venkateswaran et al. GENES & DEVELOPMENT
- Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression
- (2019) Weronika Duda et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study
- (2019) Georgina V Long et al. LANCET ONCOLOGY
- Inhibition of serotonin synthesis: A novel therapeutic paradigm
- (2019) Michael Bader PHARMACOLOGY & THERAPEUTICS
- Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case–control study
- (2019) Romain Colle et al. PSYCHIATRY AND CLINICAL NEUROSCIENCES
- Pyridine-2,3-dicarboxylate, quinolinic acid, induces 1N4R Tau amyloid aggregation in vitro: Another evidence for the detrimental effect of the inescapable endogenous neurotoxin
- (2019) Sajjad Esmaeili et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Deciphering midbrain mechanisms underlying prepulse inhibition of startle
- (2019) Niveen Fulcher et al. PROGRESS IN NEUROBIOLOGY
- Tryptophan Metabolism: A Link Between the Gut Microbiota and Brain
- (2019) Kan Gao et al. Advances in Nutrition
- Tryptophan Metabolism by Gut Microbiome and Gut-Brain-Axis: An in silico Analysis
- (2019) Harrisham Kaur et al. Frontiers in Neuroscience
- Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma
- (2019) Soumya R. Mohapatra et al. Frontiers in Immunology
- Glucosinolate and isothiocyanate intakes are inversely associated with breast cancer risk: a case–control study in China
- (2018) Nai-Qi Zhang et al. BRITISH JOURNAL OF NUTRITION
- IDO1 in cancer: a Gemini of immune checkpoints
- (2018) Lijie Zhai et al. Cellular & Molecular Immunology
- Immunobiochemical pathways of neopterin formation and tryptophan breakdown via indoleamine 2,3-dioxygenase correlate with circulating tumor cells in ovarian cancer patients– A study of the OVCAD consortium
- (2018) Johanna M. Gostner et al. GYNECOLOGIC ONCOLOGY
- Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis
- (2018) M Anthony Sofia et al. INFLAMMATORY BOWEL DISEASES
- 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells
- (2018) Xiuting Liu et al. INTERNATIONAL JOURNAL OF CANCER
- Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors
- (2018) Anthony R. Guastella et al. JOURNAL OF NEURO-ONCOLOGY
- Bioavailability of Glucoraphanin and Sulforaphane from High-Glucoraphanin Broccoli
- (2018) Tharsini Sivapalan et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme
- (2018) Todd A Triplett et al. NATURE BIOTECHNOLOGY
- Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health
- (2018) Ludivine Laurans et al. NATURE MEDICINE
- Peripheral Serotonin Synthesis as a New Drug Target
- (2018) Susann Matthes et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Challenging PD-L1 expressing cytotoxic T cells as a predictor for response to immunotherapy in melanoma
- (2018) Lieve Brochez et al. Nature Communications
- Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in Rats
- (2018) Mathilde Jaglin et al. Frontiers in Neuroscience
- Mechanism and prognostic value of indoleamine 2,3-dioxygenase 1 expressed in hepatocellular carcinoma
- (2018) Shaolong Li et al. CANCER SCIENCE
- Microbial tryptophan catabolites in health and disease
- (2018) Henrik M. Roager et al. Nature Communications
- Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins
- (2018) Cláudia Marques et al. Scientific Reports
- 5-hydroxytryptamine receptor 1D aggravates hepatocellular carcinoma progression via FoxO6 in AKT-dependent and independent manners
- (2018) Xueliang Zuo et al. HEPATOLOGY
- Differential expression of PD-L1 and IDO1 in association with the immune microenvironment in resected lung adenocarcinomas
- (2018) M. Lisa Zhang et al. MODERN PATHOLOGY
- Increased quinolinic acid in peripheral mononuclear cells in Alzheimer’s dementia
- (2017) Mandy Busse et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases
- (2017) Susanna Nikolaus et al. GASTROENTEROLOGY
- Changes in kynurenine pathway metabolism in Parkinson patients with L-DOPA-induced dyskinesia
- (2017) Jesper F. Havelund et al. JOURNAL OF NEUROCHEMISTRY
- Feedback control of AHR signalling regulates intestinal immunity
- (2017) Chris Schiering et al. NATURE
- Involvement of the kynurenine pathway in the pathogenesis of Parkinson’s disease
- (2017) Chai K. Lim et al. PROGRESS IN NEUROBIOLOGY
- Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis
- (2017) Eric Plitman et al. SCHIZOPHRENIA BULLETIN
- Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts
- (2017) William D. Gwynne et al. Oncotarget
- P53 prevent tumor invasion and metastasis by down-regulating IDO in lung cancer
- (2017) Dongfang Tang et al. Oncotarget
- Serum Tryptophan Metabolite Levels During Sleep in Patients With and Without Irritable Bowel Syndrome (IBS)
- (2016) Margaret M. Heitkemper et al. Biological Research for Nursing
- Altered tryptophan metabolism in human meningioma
- (2016) Noble Kumar Talari et al. JOURNAL OF NEURO-ONCOLOGY
- Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis
- (2016) Damian J Mole et al. NATURE MEDICINE
- Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
- (2016) Veit Rothhammer et al. NATURE MEDICINE
- CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
- (2016) Bruno Lamas et al. NATURE MEDICINE
- Tryptophan Metabolism and White Matter Integrity in Schizophrenia
- (2016) Joshua Chiappelli et al. NEUROPSYCHOPHARMACOLOGY
- IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
- (2016) David H. Munn et al. TRENDS IN IMMUNOLOGY
- Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis
- (2016) Ya-Ling Hsu et al. Oncotarget
- Blocking peripheral serotonin synthesis by telotristat etiprate (LX1032/LX1606) reduces severity of both chemical- and infection-induced intestinal inflammation
- (2015) Janice J. Kim et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
- (2015) S.M. O’Mahony et al. BEHAVIOURAL BRAIN RESEARCH
- A TDO2-AhR Signaling Axis Facilitates Anoikis Resistance and Metastasis in Triple-Negative Breast Cancer
- (2015) Nicholas C. D'Amato et al. CANCER RESEARCH
- Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
- (2015) Jessica M. Yano et al. CELL
- Prognostic Significance of Tryptophan Catabolism in Adult T-cell Leukemia/Lymphoma
- (2015) A. Masaki et al. CLINICAL CANCER RESEARCH
- Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells
- (2015) Christopher S. Reigstad et al. FASEB JOURNAL
- Aryl hydrocarbon receptor mediates both proinflammatory and anti-inflammatory effects in lipopolysaccharide-activated microglia
- (2015) Yi-Hsuan Lee et al. GLIA
- Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes
- (2015) Isabella Caroline da Silva Dias et al. MOLECULAR NEUROBIOLOGY
- Prognostic significance of kynurenine 3-monooxygenase and effects on proliferation, migration and invasion of human hepatocellular carcinoma
- (2015) Haojie Jin et al. Scientific Reports
- Indoleamine 2,3-dioxygenase (IDO) is frequently expressed in stromal cells of Hodgkin lymphoma and is associated with adverse clinical features: a retrospective cohort study
- (2014) Ji-Young Choe et al. BMC CANCER
- Inhibition of De Novo NAD + Synthesis by Oncogenic URI Causes Liver Tumorigenesis through DNA Damage
- (2014) Krishna S. Tummala et al. CANCER CELL
- Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment
- (2014) Yuko Tanizaki et al. CANCER SCIENCE
- Durable Therapeutic Efficacy Utilizing Combinatorial Blockade against IDO, CTLA-4, and PD-L1 in Mice with Brain Tumors
- (2014) D. A. Wainwright et al. CLINICAL CANCER RESEARCH
- Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway
- (2014) Martina Ott et al. GLIA
- Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
- (2014) Madhukumar Venkatesh et al. IMMUNITY
- Clinical Significance of Tryptophan Metabolism in the Nontumoral Hemisphere in Patients with Malignant Glioma
- (2014) D. O. Kamson et al. JOURNAL OF NUCLEAR MEDICINE
- Citalopram decreases tryptophan 2,3-dioxygenase activity and brain 5-HT turnover in swim stressed rats
- (2014) Iffat Ara et al. Pharmacological Reports
- IDO1 and IDO2 Non-Synonymous Gene Variants: Correlation with Crohn's Disease Risk and Clinical Phenotype
- (2014) Alexander Lee et al. PLoS One
- Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats
- (2014) Ana Pocivavsek et al. PSYCHOPHARMACOLOGY
- Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome
- (2014) Paul J. Kennedy et al. PSYCHOPHARMACOLOGY
- Influence of kynurenine 3-monooxygenase (KMO) gene polymorphism on cognitive function in schizophrenia
- (2014) Ikwunga Wonodi et al. SCHIZOPHRENIA RESEARCH
- The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress
- (2013) F. Sahm et al. CANCER RESEARCH
- IDO1 Metabolites Activate β-catenin Signaling to Promote Cancer Cell Proliferation and Colon Tumorigenesis in Mice
- (2013) Ameet I. Thaker et al. GASTROENTEROLOGY
- Decreased levels of kynurenic acid in the intestinal mucosa of IBS patients: Relation to serotonin and psychological state
- (2013) Daniel Keszthelyi et al. JOURNAL OF PSYCHOSOMATIC RESEARCH
- Up-regulated expression of indoleamine 2,3-dioxygenase 1 in non-Hodgkin lymphoma correlates with increased regulatory T-cell infiltration
- (2013) Xiao-Qian Liu et al. LEUKEMIA & LYMPHOMA
- The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1 and with increased CSF KYNA level and reduced KMO expression
- (2013) C Lavebratt et al. MOLECULAR PSYCHIATRY
- Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism
- (2013) Ivan Vujkovic-Cvijin et al. Science Translational Medicine
- Immunological and Nonimmunological Effects of Indoleamine 2,3-Dioxygenase on Breast Tumor Growth and Spontaneous Metastasis Formation
- (2012) Vera Levina et al. Clinical & Developmental Immunology
- Quantitative PET Imaging of Tryptophan Accumulation in Gliomas and Remote Cortex
- (2012) Csaba Juhász et al. CLINICAL NUCLEAR MEDICINE
- Altered Cognitive Function of Prefrontal Cortex During Error Feedback in Patients With Irritable Bowel Syndrome, Based on fMRI and Dynamic Causal Modeling
- (2012) Emiko Aizawa et al. GASTROENTEROLOGY
- The gut microbiota regulates bone mass in mice
- (2012) Klara Sjögren et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
- (2012) G Clarke et al. MOLECULAR PSYCHIATRY
- Kynurenines in the CNS: recent advances and new questions
- (2012) László Vécsei et al. NATURE REVIEWS DRUG DISCOVERY
- Downregulated Kynurenine 3-Monooxygenase Gene Expression and Enzyme Activity in Schizophrenia and Genetic Association With Schizophrenia Endophenotypes
- (2011) Ikwunga Wonodi ARCHIVES OF GENERAL PSYCHIATRY
- Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naïve and medication-free schizophrenic patients
- (2011) A.M. Myint et al. BRAIN BEHAVIOR AND IMMUNITY
- Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer
- (2011) L Ferdinande et al. BRITISH JOURNAL OF CANCER
- Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration
- (2011) Daniel Zwilling et al. CELL
- High expression of indoleamine 2,3-dioxygenase in the tumour is associated with medullary features and favourable outcome in basal-like breast carcinoma
- (2011) Jocelyne Jacquemier et al. INTERNATIONAL JOURNAL OF CANCER
- 3-Hydroxykynurenine and clinical symptoms in first-episode neuroleptic-naive patients with schizophrenia
- (2011) Ruth Condray et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Activated CD69+ T Cells Foster Immune Privilege by Regulating IDO Expression in Tumor-Associated Macrophages
- (2011) Q. Zhao et al. JOURNAL OF IMMUNOLOGY
- Auxin Biosynthesis: A Simple Two-Step Pathway Converts Tryptophan to Indole-3-Acetic Acid in Plants
- (2011) Yunde Zhao Molecular Plant
- An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
- (2011) Christiane A. Opitz et al. NATURE
- Distribution, function and physiological role of melatonin in the lower gut
- (2011) Chun-Qiu Chen WORLD JOURNAL OF GASTROENTEROLOGY
- Kynurenine and its metabolites in Alzheimer's disease patients
- (2010) E Gulaj et al. Advances in Medical Sciences
- Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells
- (2010) Noura M. El Kholy et al. MEDICAL ONCOLOGY
- Targeting anoikis resistance in prostate cancer metastasis
- (2010) Shinichi Sakamoto et al. MOLECULAR ASPECTS OF MEDICINE
- Hydroxyamidine Inhibitors of Indoleamine-2,3-dioxygenase Potently Suppress Systemic Tryptophan Catabolism and the Growth of IDO-Expressing Tumors
- (2010) H. K. Koblish et al. MOLECULAR CANCER THERAPEUTICS
- The Role of Tryptophan Catabolism along the Kynurenine Pathway in Acute Ischemic Stroke
- (2010) Raf Brouns et al. NEUROCHEMICAL RESEARCH
- LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin
- (2010) M. Camilleri NEUROGASTROENTEROLOGY AND MOTILITY
- Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome
- (2010) David M. Christmas et al. NUTRITION RESEARCH
- Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease
- (2010) David J. Bonda et al. REDOX REPORT
- Increased Levels of Kynurenine and Kynurenic Acid in the CSF of Patients With Schizophrenia
- (2010) K. R. Linderholm et al. SCHIZOPHRENIA BULLETIN
- Serotonin: a regulator of neuronal morphology and circuitry
- (2010) Elizabeth A. Daubert et al. TRENDS IN NEUROSCIENCES
- Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis
- (2009) J. Rodgers et al. BRAIN
- Serotonin Has a Key Role in Pathogenesis of Experimental Colitis
- (2009) Jean–Eric Ghia et al. GASTROENTEROLOGY
- Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinoma
- (2009) Tomoko Inaba et al. GYNECOLOGIC ONCOLOGY
- Imaging Correlates of Differential Expression of Indoleamine 2,3-Dioxygenase in Human Brain Tumors
- (2009) Carlos E. A. Batista et al. MOLECULAR IMAGING AND BIOLOGY
- Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
- (2009) W. R. Wikoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overexpression of Indoleamine 2,3-Dioxygenase in Human Endometrial Carcinoma Cells Induces Rapid Tumor Growth in a Mouse Xenograft Model
- (2008) N. Yoshida et al. CLINICAL CANCER RESEARCH
- Inverse Correlation between Tumoral Indoleamine 2,3-Dioxygenase Expression and Tumor-Infiltrating Lymphocytes in Endometrial Cancer: Its Association with Disease Progression and Survival
- (2008) K. Ino et al. CLINICAL CANCER RESEARCH
- Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinoma
- (2008) Ke Pan et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Expression of Indoleamine 2,3-Dioxygenase in Metastatic Pancreatic Ductal Adenocarcinoma Recruits Regulatory T Cells to Avoid Immune Detection
- (2008) Agnes Witkiewicz et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started