Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

(2015) Simon P. Jones et al.   PLoS One

Scavenging of reactive oxygen species by tryptophan metabolites helps Pseudomonas aeruginosa escape neutrophil killing

(2014) Charlotte Genestet et al.   FREE RADICAL BIOLOGY AND MEDICINE

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Activation of NAD(P)H Oxidase by Tryptophan-Derived 3-Hydroxykynurenine Accelerates Endothelial Apoptosis and Dysfunction In Vivo

(2013) Qiongxin Wang et al.   CIRCULATION RESEARCH

Targeted Deletion of Kynurenine 3-Monooxygenase in Mice

(2013) Flaviano Giorgini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality

(2013) Hong Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural basis of kynurenine 3-monooxygenase inhibition

(2013) Marta Amaral et al.   NATURE

Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery

(2012) Flavio Moroni et al.   JOURNAL OF NEURAL TRANSMISSION

Data processing and analysis with theautoPROCtoolbox

(2011) Clemens Vonrhein et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

(2011) Daniel Zwilling et al.   CELL

Kynurenine metabolism predicts cognitive function in patients following cardiac bypass and thoracic surgery

(2011) Caroline M. Forrest et al.   JOURNAL OF NEUROCHEMISTRY

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Interleukin-1β: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis

(2011) Patricia A Zunszain et al.   NEUROPSYCHOPHARMACOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Development of a microplate fluorescence assay for kynurenine aminotransferase

(2010) Jacky Wong et al.   ANALYTICAL BIOCHEMISTRY

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Kynurenine is an endothelium-derived relaxing factor produced during inflammation

(2010) Yutang Wang et al.   NATURE MEDICINE

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records

(2010) Damian J. Mole et al.   HPB

INCREASED PLASMA KYNURENINE VALUES AND KYNURENINE-TRYPTOPHAN RATIOS AFTER MAJOR TRAUMA ARE EARLY INDICATORS FOR THE DEVELOPMENT OF SEPSIS

(2009) Tim T. Lögters et al.   SHOCK

The kynurenines are associated with oxidative stress, inflammation and the prevalence of cardiovascular disease in patients with end-stage renal disease

(2008) Krystyna Pawlak et al.   ATHEROSCLEROSIS

Tryptophan catabolites in mesenteric lymph may contribute to pancreatitis-associated organ failure

(2008) D. J. Mole et al.   BRITISH JOURNAL OF SURGERY

Differential Preservation of Lipopolysaccharide-Induced Chemokine/Cytokine Expression during Experimental Pancreatitis-Associated Organ Failure in Rats Shows a Regulatory Expressed Phenotype

(2008) Damian J. Mole et al.   PANCREATOLOGY