Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors

CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014

(2017) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor

(2017) Benjamin J. Moyer et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Altered tryptophan metabolism in human meningioma

(2016) Noble Kumar Talari et al.   JOURNAL OF NEURO-ONCOLOGY

Epidemiology of Brain Tumors

(2016) Katharine A. McNeill   NEUROLOGIC CLINICS

Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer

(2016) Srikanth Santhanam et al.   Translational Research

Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer

(2016) Josephine F. Trott et al.   Oncotarget

Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma

(2016) Anthony R. Guastella et al.   Molecular Imaging

A TDO2-AhR Signaling Axis Facilitates Anoikis Resistance and Metastasis in Triple-Negative Breast Cancer

(2015) Nicholas C. D'Amato et al.   CANCER RESEARCH

Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway

(2015) Un-Ho Jin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Development of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1

(2015) Sharon K Michelhaugh et al.   Journal of Translational Medicine

Genomic profiling of a Hepatocyte growth factor-dependent signature for MET-targeted therapy in glioblastoma

(2015) Jennifer Johnson et al.   Journal of Translational Medicine

Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas

(2015) E. Bosnyak et al.   NEURO-ONCOLOGY

Understanding the role of the kynurenine pathway in human breast cancer immunobiology

(2015) Benjamin Heng et al.   Oncotarget

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

(2015) Ulrike M. Litzenburger et al.   Oncotarget

Benzyl butyl phthalate induces migration, invasion, and angiogenesis of Huh7 hepatocellular carcinoma cells through nongenomic AhR/G-protein signaling

(2014) Cheng-Fang Tsai et al.   BMC CANCER

Targeting adaptive glioblastoma: an overview of proliferation and invasion

(2014) Q. Xie et al.   NEURO-ONCOLOGY

Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology

(2014) Seray Adams et al.   PLoS One

The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90

(2014) Noriko Tsuji et al.   FEBS Open Bio

In vivo metabolism of tryptophan in meningiomas is mediated by indoleamine 2,3-dioxygenase 1

(2013) Ian M. Zitron et al.   CANCER BIOLOGY & THERAPY

Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk

(2013) S.-C. Chuang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Causes, consequences, and reversal of immune system aging

(2013) Encarnacion Montecino-Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of the Aryl Hydrocarbon Receptor in Carcinogenesis and Potential as a Drug Target

(2013) Stephen Safe et al.   TOXICOLOGICAL SCIENCES

Tryptophan metabolism in breast cancers: molecular imaging and immunohistochemistry studies

(2012) Csaba Juhász et al.   NUCLEAR MEDICINE AND BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The kynurenine system and immunoregulation

(2011) Yvette Mándi et al.   JOURNAL OF NEURAL TRANSMISSION

Increased tryptophan transport in epileptogenic dysembryoplastic neuroepithelial tumors

(2011) Bálint Alkonyi et al.   JOURNAL OF NEURO-ONCOLOGY

Hydroxyurea for recurrent surgery and radiation refractory high-grade meningioma

(2011) Marc C. Chamberlain   JOURNAL OF NEURO-ONCOLOGY

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling

(2010) Brett C. DiNatale et al.   TOXICOLOGICAL SCIENCES

Advances in meningioma therapy

(2009) Andrew D. Norden et al.   Current Neurology and Neuroscience Reports

Imaging Correlates of Differential Expression of Indoleamine 2,3-Dioxygenase in Human Brain Tumors

(2009) Carlos E. A. Batista et al.   MOLECULAR IMAGING AND BIOLOGY

Aryl hydrocarbon receptor inhibition downregulates the TGF-β/Smad pathway in human glioblastoma cells

(2009) D Gramatzki et al.   ONCOGENE

Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase

(2008) Christoph F.A. Vogel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Low-grade gliomas in adults

(2008) Sandeep Mittal et al.   Current Treatment Options in Neurology