GPER-mediated stabilization of HIF-1α contributes to upregulated aerobic glycolysis in tamoxifen-resistant cells
出版年份 2022 全文链接
标题
GPER-mediated stabilization of HIF-1α contributes to upregulated aerobic glycolysis in tamoxifen-resistant cells
作者
关键词
-
出版物
ONCOGENE
Volume 42, Issue 3, Pages 184-197
出版商
Springer Science and Business Media LLC
发表日期
2022-11-18
DOI
10.1038/s41388-022-02506-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Abnormal saccharides affecting cancer multi-drug resistance (MDR) and the reversal strategies
- (2021) Meizhu Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The Key Role of the WNT/β-Catenin Pathway in Metabolic Reprogramming in Cancers under Normoxic Conditions
- (2021) Alexandre Vallée et al. Cancers
- GPER-1 expression is associated with a decreased response rate to primary tamoxifen therapy of breast cancer patients
- (2020) Tanja Ignatov et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Metabolic Symbiosis in Chemoresistance: Refocusing the Role of Aerobic Glycolysis
- (2020) Lisi Ma et al. Frontiers in Oncology
- GPER mediates decreased chemosensitivity via regulation of ABCG2 expression and localization in tamoxifen-resistant breast cancer cells
- (2020) Tenghua Yu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges
- (2020) David Barua et al. CANCER LETTERS
- The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs)
- (2020) Rosamaria Lappano et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Regulation of glycolysis by the hypoxia‐inducible factor (HIF): implications for cellular physiology
- (2020) S. J. Kierans et al. JOURNAL OF PHYSIOLOGY-LONDON
- HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice
- (2020) Rouven Hoefflin et al. Nature Communications
- Continuous Exposure of Breast Cancer Cells to Tamoxifen Upregulates GPER-1 and Increases Cell Proliferation
- (2020) Luis Molina et al. Frontiers in Endocrinology
- Revisiting the Warburg effect: historical dogma versus current understanding
- (2020) Peter Vaupel et al. JOURNAL OF PHYSIOLOGY-LONDON
- Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer
- (2020) Jingwei Yao et al. Frontiers in Pharmacology
- G-Protein Coupled Estrogen Receptor in Breast Cancer
- (2019) Li-Han Hsu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells
- (2019) Mengjia He et al. ONCOGENE
- Lactate dehydrogenase A regulates autophagy and tamoxifen resistance in breast cancer
- (2019) Chandan Kanta Das et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Elevated Hexokinase II Expression Confers Acquired Resistance to 4-Hydroxytamoxifen in Breast Cancer Cells
- (2019) Xiaochuan Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- Non-canonical Estrogen Signaling in Endocrine Resistance
- (2019) Prathibha Ranganathan et al. Frontiers in Endocrinology
- The association between type of endocrine therapy and development of estrogen receptor-1 mutation(s) in patients with hormone-sensitive advanced breast cancer: A systematic review and meta-analysis of randomized and non-randomized trials
- (2019) Omar Najim et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy
- (2019) Ali F. Abdel-Wahab et al. PHARMACOLOGICAL RESEARCH
- Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer
- (2019) Annika Jögi et al. PLoS One
- Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMT
- (2018) Ernestina De Francesco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- G-protein-coupled estrogen receptor GPER-1 expression in hormone receptor-positive breast cancer is associated with poor benefit of tamoxifen
- (2018) Tanja Ignatov et al. BREAST CANCER RESEARCH AND TREATMENT
- Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries
- (2017) Kevin K. Wang et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Estrogen stabilizes hypoxia-inducible factor 1α through G protein-coupled estrogen receptor 1 in eutopic endometrium of endometriosis
- (2017) Ling Zhang et al. FERTILITY AND STERILITY
- GPER promotes tamoxifen-resistance in ER+ breast cancer cells by reduced Bim proteins through MAPK/Erk-TRIM2 signaling axis
- (2017) Heng Yin et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- UCH-L1-containing exosomes mediate chemotherapeutic resistance transfer in breast cancer
- (2017) Kuan Ning et al. JOURNAL OF SURGICAL ONCOLOGY
- AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment
- (2016) N. A. Daurio et al. CANCER RESEARCH
- The G protein-coupled estrogen receptor as a modulator of neoplastic transformation
- (2016) Damian Jacenik et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance
- (2016) T Yu et al. ONCOGENE
- HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells
- (2016) Muhammad Wasi Alam et al. Oncotarget
- Overexpression of ubiquitin carboxyl terminal hydrolase-L1 enhances multidrug resistance and invasion/metastasis in breast cancer by activating the MAPK/Erk signaling pathway
- (2015) Wenjuan Wang et al. MOLECULAR CARCINOGENESIS
- Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
- (2015) Jun Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α
- (2015) Yoko Goto et al. Nature Communications
- Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells
- (2015) Yu Mi Woo et al. PLoS One
- Lack of G protein-coupled estrogen receptor (GPER) in the plasma membrane is associated with excellent long-term prognosis in breast cancer
- (2014) Martin Sjöström et al. BREAST CANCER RESEARCH AND TREATMENT
- Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth
- (2014) Stefania Catalano et al. BREAST CANCER RESEARCH AND TREATMENT
- GPER Mediates Activation of HIF1 /VEGF Signaling by Estrogens
- (2014) E. M. De Francesco et al. CANCER RESEARCH
- Prognostic relevance of ubiquitin C-terminal hydrolase L1 (UCH-L1) mRNA and protein expression in breast cancer patients
- (2013) Christine Schröder et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Dose-dependent effect of tamoxifen in tamoxifen-resistant breast cancer cells via stimulation by the ERK1/2 and AKT signaling pathways
- (2013) LI-JUAN WANG et al. ONCOLOGY REPORTS
- Tamoxifen Resistance in Breast Cancer
- (2012) Min-Sun Chang Biomolecules & Therapeutics
- A phase I dose-escalation trial of 2-deoxy-d-glucose alone or combined with docetaxel in patients with advanced solid tumors
- (2012) Luis E. Raez et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- G-protein-coupled estrogen receptor GPR30 and tamoxifen resistance in breast cancer
- (2011) Atanas Ignatov et al. BREAST CANCER RESEARCH AND TREATMENT
- Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer
- (2011) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- The G Protein-coupled Receptor 30 Is Up-regulated by Hypoxia-inducible Factor-1α (HIF-1α) in Breast Cancer Cells and Cardiomyocytes
- (2011) Anna Grazia Recchia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells
- (2009) Atanas Ignatov et al. BREAST CANCER RESEARCH AND TREATMENT
- Enhancement of vascular endothelial growth factor-mediated angiogenesis in tamoxifen-resistant breast cancer cells: role of Pin1 overexpression
- (2009) M. R. Kim et al. MOLECULAR CANCER THERAPEUTICS
- Phosphorylated ERα, HIF-1α, and MAPK Signaling As Predictors of Primary Endocrine Treatment Response and Resistance in Patients With Breast Cancer
- (2008) Daniele Generali et al. JOURNAL OF CLINICAL ONCOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started