Gas6 Promotes Microglia Efferocytosis and Suppresses Inflammation Through Activating Axl/Rac1 Signaling in Subarachnoid Hemorrhage Mice

Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells

(2022) Alexandra L. McCubbrey et al.   Cell Reports

Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence

(2022) Sarah Rose Anderson et al.   eLife

High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke

(2021) Mengyan Hu et al.   Journal of Neuroinflammation

Cellular Responses to the Efferocytosis of Apoptotic Cells

(2021) Charles Yin et al.   Frontiers in Immunology

AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury

(2021) Hang Zhou et al.   Journal of Neuroinflammation

microRNA-455-5p alleviates neuroinflammation in cerebral ischemia/reperfusion injury

(2021) Qi-Yong Mei et al.   Neural Regeneration Research

Sirtuin 5-Mediated Lysine Desuccinylation Protects Mitochondrial Metabolism Following Subarachnoid Hemorrhage in Mice

(2021) Zhi-Peng Xiao et al.   STROKE

Disruption of auto-inhibition underlies conformational signaling of ASIC1a to induce neuronal necroptosis

(2020) Jing-Jing Wang et al.   Nature Communications

Microglial Corpse Clearance: Lessons From Macrophages

(2020) Mar Márquez-Ropero et al.   Frontiers in Immunology

Aneurysmal Subarachnoid Hemorrhage: the Last Decade

(2020) Sean N. Neifert et al.   Translational Stroke Research

Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment

(2019) Kayla V. Myers et al.   Molecular Cancer

Macrophages reprogram after ischemic stroke and promote efferocytosis and inflammation resolution in the mouse brain

(2019) Wenting Zhang et al.   CNS Neuroscience & Therapeutics

Axl activation attenuates neuroinflammation by inhibiting the TLR/TRAF/NF-κB pathway after MCAO in rats

(2018) Guangyong Wu et al.   NEUROBIOLOGY OF DISEASE

Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6

(2017) Ke Geng et al.   Frontiers in Immunology

Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice

(2016) Jihye Han et al.   Autophagy

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

(2015) Jonathan J Miner et al.   NATURE MEDICINE

Neuroprotective role of an N-acetyl serotonin derivative via activation of tropomyosin-related kinase receptor B after subarachnoid hemorrhage in a rat model

(2015) Junjia Tang et al.   NEUROBIOLOGY OF DISEASE

Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells

(2015) I Dransfield et al.   Cell Death & Disease

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

(2014) J. H. M. van der Meer et al.   BLOOD

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Targeted GAS6 Delivery to the CNS Protects Axons from Damage during Experimental Autoimmune Encephalomyelitis

(2014) Ross C. Gruber et al.   JOURNAL OF NEUROSCIENCE

Axl Phosphorylates Elmo Scaffold Proteins To Promote Rac Activation and Cell Invasion

(2014) Afnan Abu-Thuraia et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

(2011) Jason G Weinger et al.   Journal of Neuroinflammation

Gas6 Deficiency Increases Oligodendrocyte Loss and Microglial Activation in Response to Cuprizone-Induced Demyelination

(2008) M. D. Binder et al.   JOURNAL OF NEUROSCIENCE