Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression
出版年份 2022 全文链接
标题
Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression
作者
关键词
-
出版物
Nature Communications
Volume 13, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-09-07
DOI
10.1038/s41467-022-32972-z
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pathophysiology of diabetic kidney disease: impact of SGLT2 inhibitors
- (2021) Ralph A. DeFronzo et al. Nature Reviews Nephrology
- Comprehensive analysis of single cell ATAC-seq data with SnapATAC
- (2021) Rongxin Fang et al. Nature Communications
- A practical solution to pseudoreplication bias in single-cell studies
- (2021) Kip D. Zimmerman et al. Nature Communications
- US Renal Data System 2020 Annual Data Report: Epidemiology of Kidney Disease in the United States
- (2021) Kirsten L. Johansen et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Interpretation of allele-specific chromatin accessibility using cell state–aware deep learning
- (2021) Zeynep Kalender Atak et al. GENOME RESEARCH
- Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
- (2021) Joshua Chiou et al. NATURE
- Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
- (2021) Yoshiharu Muto et al. Nature Communications
- Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study
- (2021) L. J. Smyth et al. Clinical Epigenetics
- MHC class II in renal tubules plays an essential role in renal fibrosis
- (2021) Yunfeng Zhou et al. Cellular & Molecular Immunology
- Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
- (2021) Xin Sheng et al. NATURE GENETICS
- Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
- (2021) Dan Liang et al. NATURE NEUROSCIENCE
- Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci
- (2020) Maria Gutierrez-Arcelus et al. NATURE GENETICS
- ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing
- (2020) Jiaxin Fan et al. PLoS Genetics
- Expanded encyclopaedias of DNA elements in the human and mouse genomes
- (2020) Jill E. Moore et al. NATURE
- Unravelling the complex genetics of common kidney diseases: from variants to mechanisms
- (2020) Katie Marie Sullivan et al. Nature Reviews Nephrology
- Enhancer RNAs are an important regulatory layer of the epigenome
- (2020) Vittorio Sartorelli et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury
- (2020) Yuhei Kirita et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin
- (2020) Sai Ma et al. CELL
- An efficient KRAB domain for CRISPRi applications in human cells
- (2020) Nader Alerasool et al. NATURE METHODS
- Renal gluconeogenesis: an underestimated role of the kidney in systemic glucose metabolism
- (2020) David Legouis et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Glucose Metabolism in the Kidney: Neurohormonal Activation and Heart Failure Development
- (2020) Edoardo Gronda et al. Journal of the American Heart Association
- C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution
- (2019) Tsukasa Kouno et al. Nature Communications
- Epigenetics and epigenomics in diabetic kidney disease and metabolic memory
- (2019) Mitsuo Kato et al. Nature Reviews Nephrology
- DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
- (2019) Christopher S. McGinnis et al. Cell Systems
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- A catalog of genetic loci associated with kidney function from analyses of a million individuals
- (2019) Matthias Wuttke et al. NATURE GENETICS
- Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
- (2019) Caroline Gluck et al. Nature Communications
- NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements
- (2019) Shigeki Hirabayashi et al. NATURE GENETICS
- Mechanisms of hypoxia signalling: new implications for nephrology
- (2019) Johannes Schödel et al. Nature Reviews Nephrology
- The single-cell transcriptomic landscape of early human diabetic nephropathy
- (2019) Parker C. Wilson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression
- (2019) Ying Fan et al. DIABETES
- FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury
- (2019) Monica Chang-Panesso et al. JOURNAL OF CLINICAL INVESTIGATION
- Fast, sensitive and accurate integration of single-cell data with Harmony
- (2019) Ilya Korsunsky et al. NATURE METHODS
- GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
- (2019) Raha Pazoki et al. Nature Communications
- Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program
- (2019) Jacklyn N. Hellwege et al. Nature Communications
- Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria
- (2019) Alexander Teumer et al. Nature Communications
- Accurate, scalable and integrative haplotype estimation
- (2019) Olivier Delaneau et al. Nature Communications
- Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures
- (2019) Vivek Rai et al. Molecular Metabolism
- A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
- (2018) Natalie R. van Zuydam et al. DIABETES
- FKBP5 polymorphism is associated with insulin resistance in children and adolescents with obesity
- (2018) Marta Fichna et al. Obesity Research & Clinical Practice
- Structural absorption by barbule microstructures of super black bird of paradise feathers
- (2018) Dakota E. McCoy et al. Nature Communications
- Type 2 diabetes and cardiometabolic risk may be associated with increase in DNA methylation of FKBP5
- (2018) Robin Ortiz et al. Clinical Epigenetics
- Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data
- (2018) Hannah A. Pliner et al. MOLECULAR CELL
- chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
- (2017) Alicia N Schep et al. NATURE METHODS
- An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
- (2017) M Ryan Corces et al. NATURE METHODS
- JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
- (2017) Aziz Khan et al. NUCLEIC ACIDS RESEARCH
- An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites
- (2017) Peter J Skene et al. eLife
- Fitting Linear Mixed-Effects Models Usinglme4
- (2015) Douglas Bates et al. Journal of Statistical Software
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- WASP: allele-specific software for robust molecular quantitative trait locus discovery
- (2015) Bryce van de Geijn et al. NATURE METHODS
- Gene–Stress–Epigenetic Regulation of FKBP5: Clinical and Translational Implications
- (2015) Anthony S Zannas et al. NEUROPSYCHOPHARMACOLOGY
- Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds
- (2015) Nora Sundahl et al. PHARMACOLOGY & THERAPEUTICS
- An atlas of active enhancers across human cell types and tissues
- (2014) Robin Andersson et al. NATURE
- Aldosterone regulates Na+, K+ ATPase activity in human renal proximal tubule cells through mineralocorticoid receptor
- (2013) Sarah A. Salyer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Steroid-induced diabetes: a clinical and molecular approach to understanding and treatment
- (2013) Jessica L. Hwang et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney disease
- (2013) Laura J Smyth et al. Epigenetics
- Deletion of the Insulin Receptor in the Proximal Tubule Promotes Hyperglycemia
- (2013) S. Tiwari et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development
- (2013) Yi-An Ko et al. GENOME BIOLOGY
- Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding
- (2011) Simon C. Biddie et al. MOLECULAR CELL
- Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
- (2011) Sam John et al. NATURE GENETICS
- Reconsidering the Roles of the Mineralocorticoid Receptor
- (2009) John W. Funder HYPERTENSION
- Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems
- (2008) Karolien De Bosscher et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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