Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci

(2019) Karsten B. Sieber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure

(2018) Mary E. Haas et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome

(2018) Christopher E. Gillies et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic atlas of the human plasma proteome

(2018) Benjamin B. Sun et al.   NATURE

Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits

(2018) Yan Zhang et al.   NATURE GENETICS

Discovering human diabetes-risk gene function with genetics and physiological assays

(2018) Heshan Peiris et al.   Nature Communications

Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution

(2017) Reedik Mägi et al.   HUMAN MOLECULAR GENETICS

Admixture Mapping Identifies an Amerindian Ancestry Locus Associated with Albuminuria in Hispanics in the United States

(2017) Lisa A. Brown et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy

(2017) Natalie A. Afshari et al.   Nature Communications

Using the Drosophila Nephrocyte to Model Podocyte Function and Disease

(2017) Martin Helmstädter et al.   Frontiers in Pediatrics

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

(2016) Jie Zheng et al.   BIOINFORMATICS

Modeling Monogenic Human Nephrotic Syndrome in theDrosophilaGarland Cell Nephrocyte

(2016) Tobias Hermle et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

African Ancestry–Specific Alleles and Kidney Disease Risk in Hispanics/Latinos

(2016) Holly J. Kramer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Familial aggregation of albuminuria and arterial hypertension in an Aboriginal Australian community and the contribution of variants in ACE and TP53

(2016) David L. Duffy et al.   BMC Nephrology

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes

(2015) Alexander Teumer et al.   DIABETES

Dissecting the genetics of the human transcriptome identifies novel trait-relatedtrans-eQTLs and corroborates the regulatory relevance of non-protein coding loci

(2015) Holger Kirsten et al.   HUMAN MOLECULAR GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data

(2015) Kunihiro Matsushita et al.   Lancet Diabetes & Endocrinology

KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD

(2014) Lesley A. Inker et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Diabetic Kidney Disease: A Report From an ADA Consensus Conference

(2014) Katherine R. Tuttle et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes

(2014) Niina Sandholm et al.   DIABETOLOGIA

Association of Sickle Cell Trait With Chronic Kidney Disease and Albuminuria in African Americans

(2014) Rakhi P. Naik et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Drug-Induced Reduction in Albuminuria Is Associated with Subsequent Renoprotection: A Meta-Analysis

(2014) H. J. Lambers Heerspink et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis

(2014) Andrew F. Malone et al.   KIDNEY INTERNATIONAL

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Evolving importance of kidney disease: from subspecialty to global health burden

(2013) Kai-Uwe Eckardt et al.   LANCET

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

(2013) Andrew Kirby et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

GWAtoolbox: an R package for fast quality control and handling of genome-wide association studies meta-analysis data

(2011) Christian Fuchsberger et al.   BIOINFORMATICS

Associations among Estimated Glomerular Filtration Rate, Proteinuria, and Adverse Cardiovascular Outcomes

(2011) A. K. Bello et al.   Clinical Journal of the American Society of Nephrology

Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials

(2011) F. A. Holtkamp et al.   EUROPEAN HEART JOURNAL

CUBN Is a Gene Locus for Albuminuria

(2011) C. A. Boger et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts

(2011) Ron T. Gansevoort et al.   KIDNEY INTERNATIONAL

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

(2011) Rudolf S. N. Fehrmann et al.   PLoS Genetics

Heritability of Measures of Kidney Disease Among Zuni Indians: The Zuni Kidney Project

(2010) Jean W. MacCluer et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Relation Between Kidney Function, Proteinuria, and Adverse Outcomes

(2010) Brenda R. Hemmelgarn   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cubilin Is Essential for Albumin Reabsorption in the Renal Proximal Tubule

(2010) S. Amsellem et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

(2010)   LANCET

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

(2010) G. Genovese et al.   SCIENCE

Loss of Podocyte aPKC /  Causes Polarity Defects and Nephrotic Syndrome

(2009) T. B. Huber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Kazrin regulates keratinocyte cytoskeletal networks, intercellular junctions and differentiation

(2008) L. M. Sevilla et al.   JOURNAL OF CELL SCIENCE