标题
Gene–Stress–Epigenetic Regulation of FKBP5: Clinical and Translational Implications
作者
关键词
-
出版物
NEUROPSYCHOPHARMACOLOGY
Volume 41, Issue 1, Pages 261-274
出版商
Springer Nature
发表日期
2015-08-07
DOI
10.1038/npp.2015.235
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Finding the missing gene–environment interactions
- (2015) Peter Kraft et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Tetratricopeptide Repeat Domain 9A Negatively Regulates Estrogen Receptor Alpha Activity
- (2015) Smeeta Shrestha et al. International Journal of Biological Sciences
- HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children
- (2015) David Pagliaccio et al. NEUROIMAGE
- A role for synapsin in FKBP51 modulation of stress responsiveness: Convergent evidence from animal and human studies
- (2015) Ulrike Schmidt et al. PSYCHONEUROENDOCRINOLOGY
- FKBP5 moderation of depressive symptoms in peer victimized, post-institutionalized children
- (2015) Adrienne A. VanZomeren-Dohm et al. PSYCHONEUROENDOCRINOLOGY
- Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs
- (2015) Oncotarget
- Assembly of the FKBP51–PHLPP2–AKT signaling complex in cerebral ischemia/reperfusion injury in rats
- (2014) Xiu-E Wei et al. BRAIN RESEARCH
- Role of FKBP5 in emotion processing: results on amygdala activity, connectivity and volume
- (2014) Nathalie E. Holz et al. Brain Structure & Function
- Relationship of the FKBP5 C/T polymorphism with dysfunctional attitudes predisposing to depression
- (2014) Akihito Suzuki et al. COMPREHENSIVE PSYCHIATRY
- Practitioner Review: A critical perspective on gene-environment interaction models - what impact should they have on clinical perceptions and practice?
- (2014) Marcus R. Munafò et al. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
- Interplay between diet-induced obesity and chronic stress in mice: potential role of FKBP51
- (2014) Georgia Balsevich et al. JOURNAL OF ENDOCRINOLOGY
- FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance
- (2014) Maria J. Pereira et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Selective inhibitors of the FK506-binding protein 51 by induced fit
- (2014) Steffen Gaali et al. Nature Chemical Biology
- FKBP5 Moderates Alcohol Withdrawal Severity: Human Genetic Association and Functional Validation in Knockout Mice
- (2014) Ming-Chyi Huang et al. NEUROPSYCHOPHARMACOLOGY
- FKBP5 Allele-Specific Epigenetic Modification in Gene by Environment Interaction
- (2014) Torsten Klengel et al. NEUROPSYCHOPHARMACOLOGY
- FKBP5 variation is associated with the acute and chronic effects of nicotine
- (2014) K P Jensen et al. PHARMACOGENOMICS JOURNAL
- Brain-Derived Neurotrophic Factor/FK506-Binding Protein 5 Genotype by Childhood Trauma Interactions Do Not Impact on Hippocampal Volume and Cognitive Performance
- (2014) Dennis Hernaus et al. PLoS One
- Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency
- (2014) Jonathan J. Sabbagh et al. PLoS One
- Alterations in DNA methylation of Fkbp5 as a determinant of blood–brain correlation of glucocorticoid exposure
- (2014) Erin R. Ewald et al. PSYCHONEUROENDOCRINOLOGY
- Effect of the common functional FKBP5 variant (rs1360780) on the hypothalamic-pituitary-adrenal axis and peripheral blood gene expression
- (2014) Takashi Fujii et al. PSYCHONEUROENDOCRINOLOGY
- Stress-related genes and heroin addiction: A role for a functional FKBP5 haplotype
- (2014) O. Levran et al. PSYCHONEUROENDOCRINOLOGY
- Gene-environment interaction in evolutionary perspective: differential susceptibility to environmental influences
- (2014) Jay Belsky et al. World Psychiatry
- Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor
- (2014) Nicolas C Nicolaides et al. BMC Endocrine Disorders
- The common functional FKBP5 variant rs1360780 is associated with altered cognitive function in aged individuals
- (2014) Takashi Fujii et al. Scientific Reports
- Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans
- (2014) Nils C. Gassen et al. PLOS MEDICINE
- Correcting Systematic Inflation in Genetic Association Tests That Consider Interaction Effects
- (2014) Lynn M. Almli et al. JAMA Psychiatry
- The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder
- (2014) S Wilker et al. Translational Psychiatry
- Posttraumatic Stress Disorder and Posttraumatic Growth Among Adult Survivors of Wenchuan Earthquake After 1 Year: Prevalence and Correlates
- (2013) Yuchang Jin et al. ARCHIVES OF PSYCHIATRIC NURSING
- Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution
- (2013) Matthew C. Keller BIOLOGICAL PSYCHIATRY
- FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma
- (2013) Dina Collip et al. BRITISH JOURNAL OF PSYCHIATRY
- ROLE OF ALLELIC VARIANTS OF FK506-BINDING PROTEIN 51 (FKBP5) GENE IN THE DEVELOPMENT OF ANXIETY DISORDERS
- (2013) Alessandra Minelli et al. DEPRESSION AND ANXIETY
- Moderating role of FKBP5 genotype in the impact of childhood adversity on cortisol stress response during adulthood
- (2013) Arlette F. Buchmann et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Gene-environment interactions at theFKBP5locus: sensitive periods, mechanisms and pleiotropism
- (2013) A. S. Zannas et al. GENES BRAIN AND BEHAVIOR
- Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression
- (2013) A. Menke et al. GENES BRAIN AND BEHAVIOR
- FKBP5 and CRHR1 polymorphisms moderate the stress–physical health association in a national sample.
- (2013) Jared Lessard et al. HEALTH PSYCHOLOGY
- Interaction between genetic variants and exposure to Hurricane Katrina on post-traumatic stress and post-traumatic growth: A prospective analysis of low income adults
- (2013) Erin C. Dunn et al. JOURNAL OF AFFECTIVE DISORDERS
- Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
- (2013) Laura J. Blair et al. JOURNAL OF CLINICAL INVESTIGATION
- The Epigenetic Switches for Neural Development and Psychiatric Disorders
- (2013) Jingwen Lv et al. Journal of Genetics and Genomics
- Unique and Related Predictors of Major Depressive Disorder, Posttraumatic Stress Disorder, and Their Comorbidity After Hurricane Katrina
- (2013) Yael I. Nillni et al. JOURNAL OF NERVOUS AND MENTAL DISEASE
- Deficiency of FK506-binding protein (FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice
- (2013) Stefana Albu et al. JOURNAL OF SLEEP RESEARCH
- “Seq-ing” Insights into the Epigenetics of Neuronal Gene Regulation
- (2013) Francesca Telese et al. NEURON
- Stress-System Genes and Life Stress Predict Cortisol Levels and Amygdala and Hippocampal Volumes in Children
- (2013) David Pagliaccio et al. NEUROPSYCHOPHARMACOLOGY
- Epigenetics and the regulation of stress vulnerability and resilience
- (2013) A.S. Zannas et al. NEUROSCIENCE
- FKBP5 genetic variation
- (2013) Katarzyna A. Ellsworth et al. Pharmacogenetics and Genomics
- InterAKTions with FKBPs - Mutational and Pharmacological Exploration
- (2013) Anne-Katrin Fabian et al. PLoS One
- Contribution of FKBP5 Genetic Variation to Gemcitabine Treatment and Survival in Pancreatic Adenocarcinoma
- (2013) Katarzyna A. Ellsworth et al. PLoS One
- Allele-specific epigenetic modification: a molecular mechanism for gene–environment interactions in stress-related psychiatric disorders?
- (2013) Torsten Klengel et al. Epigenomics
- Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness
- (2013) Duncan Sinclair et al. Scientific Reports
- FKBP5 and Attention Bias for Threat
- (2013) Negar Fani et al. JAMA Psychiatry
- Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD
- (2013) Rachel Yehuda et al. Frontiers in Psychiatry
- Interaction Between FKBP5 and Childhood Trauma and Risk of Aggressive Behavior
- (2012) Laura Bevilacqua ARCHIVES OF GENERAL PSYCHIATRY
- Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5
- (2012) Xiaoju Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Prospect of FKBP51 as a Drug Target
- (2012) Mathias V. Schmidt et al. ChemMedChem
- FKBP5and emotional neglect interact to predict individual differences in amygdala reactivity
- (2012) M. G. White et al. GENES BRAIN AND BEHAVIOR
- Functional Changes in Myeloid-Derived Suppressor Cells (MDSCs) during Tumor Growth: FKBP51 Contributes to the Regulation of the Immunosuppressive Function of MDSCs
- (2012) Y.-S. Kim et al. JOURNAL OF IMMUNOLOGY
- Neurobiology of resilience
- (2012) Scott J Russo et al. NATURE NEUROSCIENCE
- Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
- (2012) Torsten Klengel et al. NATURE NEUROSCIENCE
- Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients
- (2012) Andreas Menke et al. NEUROPSYCHOPHARMACOLOGY
- Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment
- (2012) Joseph Boscarino et al. Neuropsychiatric Disease and Treatment
- Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans
- (2012) K. Sriram et al. PLoS Computational Biology
- Interaction ofFKBP5Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study
- (2011) Petra Zimmermann et al. AMERICAN JOURNAL OF PSYCHIATRY
- FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior
- (2011) Chadi Touma et al. BIOLOGICAL PSYCHIATRY
- Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide
- (2011) MM Kelly et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Chemical Biology of Immunophilin Ligands
- (2011) S. Gaali et al. CURRENT MEDICINAL CHEMISTRY
- Steroid up-regulation of FKBP51 and its role in hormone signaling
- (2011) Tiina Jääskeläinen et al. CURRENT OPINION IN PHARMACOLOGY
- FKBP51—a selective modulator of glucocorticoid and androgen sensitivity
- (2011) Lance A Stechschulte et al. CURRENT OPINION IN PHARMACOLOGY
- Allele-specific methylation in the human genome
- (2011) Emma L. Meaburn et al. Epigenetics
- Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior
- (2011) Alec Roy et al. JOURNAL OF PSYCHIATRIC RESEARCH
- A novel application of pattern recognition for accurate SNP and indel discovery from high-throughput data: Targeted resequencing of the glucocorticoid receptor co-chaperone FKBP5 in a Caucasian population
- (2011) Linda L. Pelleymounter et al. MOLECULAR GENETICS AND METABOLISM
- Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor
- (2011) C Anacker et al. MOLECULAR PSYCHIATRY
- Neuropsin cleaves EphB2 in the amygdala to control anxiety
- (2011) Benjamin K. Attwood et al. NATURE
- Epigenetic Status of Gdnf in the Ventral Striatum Determines Susceptibility and Adaptation to Daily Stressful Events
- (2011) Shusaku Uchida et al. NEURON
- The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress
- (2011) Jakob Hartmann et al. NEUROPHARMACOLOGY
- Moderation of Adult Depression by a Polymorphism in the FKBP5 Gene and Childhood Physical Abuse in the General Population
- (2011) Katja Appel et al. NEUROPSYCHOPHARMACOLOGY
- Expression and Regulation of the Fkbp5 Gene in the Adult Mouse Brain
- (2011) Sebastian H. Scharf et al. PLoS One
- A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51
- (2011) John C. O'Leary et al. PLoS One
- A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice
- (2011) Richard S. Lee et al. PSYCHOPHARMACOLOGY
- Epigenetic Transmission of the Impact of Early Stress Across Generations
- (2010) Tamara B. Franklin et al. BIOLOGICAL PSYCHIATRY
- Chronic Corticosterone Exposure Increases Expression and Decreases Deoxyribonucleic Acid Methylation ofFkbp5in Mice
- (2010) Richard S. Lee et al. ENDOCRINOLOGY
- Rapid Glucocorticoid Receptor-Mediated Inhibition of Hypothalamic-Pituitary-Adrenal Ultradian Activity in Healthy Males
- (2010) G. M. Russell et al. JOURNAL OF NEUROSCIENCE
- The Hsp90 Cochaperone, FKBP51, Increases Tau Stability and Polymerizes Microtubules
- (2010) U. K. Jinwal et al. JOURNAL OF NEUROSCIENCE
- Glucocorticoid Receptor Activates PoisedFKBP51Locus through Long-Distance Interactions
- (2010) Ville Paakinaho et al. MOLECULAR ENDOCRINOLOGY
- Association study between a functional polymorphism of FK506-binding protein 51 (FKBP5) gene and personality traits in healthy subjects
- (2010) Naoshi Shibuya et al. NEUROSCIENCE LETTERS
- Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders
- (2010) Yan-Feng Zou et al. NEUROSCIENCE LETTERS
- FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene–environment interaction
- (2010) Maartje P.C.M. Luijk et al. PSYCHONEUROENDOCRINOLOGY
- mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
- (2010) N. Li et al. SCIENCE
- Severe Psychological Stress in Elderly Individuals: A Proposed Model of Neurodegeneration and Its Implications
- (2009) Magda Tsolaki et al. American Journal of Alzheimers Disease and Other Dementias
- FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt
- (2009) Huadong Pei et al. CANCER CELL
- Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells
- (2009) S Romano et al. CELL DEATH AND DIFFERENTIATION
- Vulnerability genes or plasticity genes?
- (2009) J Belsky et al. MOLECULAR PSYCHIATRY
- Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
- (2008) Marcus Ising et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults
- (2008) Elisabeth B. Binder JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Activity-Dependent Suppression of Miniature Neurotransmission through the Regulation of DNA Methylation
- (2008) E. D. Nelson et al. JOURNAL OF NEUROSCIENCE
- Family-based association of FKBP5 in bipolar disorder
- (2008) V L Willour et al. MOLECULAR PSYCHIATRY
- FKBP5, SERT and COMT mRNA expressions in the peripheral leukocytes during menstruation cycle in healthy reproductive females
- (2008) Sawako Kinouchi et al. NEUROSCIENCE LETTERS
- Psychosocial Stress and Psychosis. A Review of the Neurobiological Mechanisms and the Evidence for Gene-Stress Interaction
- (2008) R. van Winkel et al. SCHIZOPHRENIA BULLETIN
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started