Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment

Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition

(2022) Chunxia Zhang et al.   Science Advances

Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development

(2022) Mainak Bose et al.   CELL

Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I

(2022) Aida Rodríguez-Nuevo et al.   NATURE

Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development

(2022) Zhuqing Xiong et al.   NATURE CELL BIOLOGY

Depletion of oocyte dynamin-related protein 1 shows maternal-effect abnormalities in embryonic development

(2022) Deepak Adhikari et al.   Science Advances

Phase Separation during Germline Development

(2021) Chun So et al.   TRENDS IN CELL BIOLOGY

The STING phase-separator suppresses innate immune signalling

(2021) Xiaoyu Yu et al.   NATURE CELL BIOLOGY

Ubiquitination is essential for recovery of cellular activities after heat shock

(2021) Brian A. Maxwell et al.   SCIENCE

Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner

(2021) Youngdae Gwon et al.   SCIENCE

The need for high-quality oocyte mitochondria at extreme ploidy dictates mammalian germline development

(2021) Marco Colnaghi et al.   eLife

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

(2021) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Liquidity Is a Critical Determinant for Selective Autophagy of Protein Condensates

(2020) Akinori Yamasaki et al.   MOLECULAR CELL

Phase separation organizes the site of autophagosome formation

(2020) Yuko Fujioka et al.   NATURE

Genome-wide analysis reveals a switch in the translational program upon oocyte meiotic resumption

(2020) Xuan G Luong et al.   NUCLEIC ACIDS RESEARCH

Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles

(2020) Jason E. Lee et al.   SCIENCE

4E-T-bound mRNAs are stored in a silenced and deadenylated form

(2020) Felix Räsch et al.   GENES & DEVELOPMENT

Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates

(2020) Yan G. Zhao et al.   DEVELOPMENTAL CELL

PABPN1L mediates cytoplasmic mRNA decay as a placeholder during the maternal‐to‐zygotic transition

(2020) Long‐Wen Zhao et al.   EMBO REPORTS

Genome transfer for the prevention of female infertility caused by maternal gene mutation

(2020) Dandan Bai et al.   Journal of Genetics and Genomics

The nucleolus as a multiphase liquid condensate

(2020) Denis L. J. Lafontaine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ZAR1 protein in cancer; from epigenetic silencing to functional characterisation and epigenetic therapy of tumour suppressors

(2020) Verena E. Deutschmeyer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Mitochondria in early development: linking the microenvironment, metabolism and the epigenome

(2019) Alexandra J Harvey   REPRODUCTION

A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes

(2019) Chun So et al.   SCIENCE

Germ granules in Drosophila

(2019) Tatjana Trcek et al.   TRAFFIC

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

(2019) Ya-Cheng Liao et al.   CELL

ELAVL2‐directed RNA regulatory network drives the formation of quiescent primordial follicles

(2019) Yuzuru Kato et al.   EMBO REPORTS

The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation

(2019) Wilton T. Snead et al.   MOLECULAR CELL

Properties of Stress Granule and P-Body Proteomes

(2019) Ji-Young Youn et al.   MOLECULAR CELL

ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation

(2019) Yan Rong et al.   NUCLEIC ACIDS RESEARCH

Impact of Oxidative Stress on Age-Associated Decline in Oocyte Developmental Competence

(2019) Hiroyuki Sasaki et al.   Frontiers in Endocrinology

Chromatin Modification and Global Transcriptional Silencing in the Oocyte Mediated by the mRNA Decay Activator ZFP36L2

(2018) Jennifer N. Dumdie et al.   DEVELOPMENTAL CELL

Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes

(2018) Tobias Brandmann et al.   EMBO JOURNAL

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

Localization of RNA and translation in the mammalian oocyte and embryo

(2018) Denisa Jansova et al.   PLoS One

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

A liquid phase of synapsin and lipid vesicles

(2018) Dragomir Milovanovic et al.   SCIENCE

Using Single Molecule mRNA Fluorescent in Situ Hybridization (RNA-FISH) to Quantify mRNAs in Individual Murine Oocytes and Embryos

(2018) Fang Xie et al.   Scientific Reports

mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation

(2018) Gangming Zhang et al.   CELL

Tdrd6a Regulates the Aggregation of Buc into Functional Subcellular Compartments that Drive Germ Cell Specification

(2018) Elke F. Roovers et al.   DEVELOPMENTAL CELL

The P Granules of C. elegans: A Genetic Model for the Study of RNA–Protein Condensates

(2018) Geraldine Seydoux   JOURNAL OF MOLECULAR BIOLOGY

Stress Granules and Processing Bodies in Translational Control

(2018) Pavel Ivanov et al.   Cold Spring Harbor Perspectives in Biology

Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells

(2018) Kathryn E Kistler et al.   eLife

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte

(2018) Qian‐Qian Sha et al.   EMBO JOURNAL

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

(2018) Christopher S. Hughes et al.   Nature Protocols

Publisher Correction: Acute and rapid degradation of endogenous proteins by Trim-Away

(2018) Dean Clift et al.   Nature Protocols

RNA-associated protein LSM family member 14 controls oocyte meiotic maturation through regulating mRNA pools

(2017) Teng ZHANG et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Insertion of inter-domain linkers improves expression and bioactivity of Zygote arrest (Zar) fusion proteins

(2017) Jonathan M. Cook et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Amyloid-like Self-Assembly of a Cellular Compartment

(2016) Elvan Boke et al.   CELL

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

mScarlet: a bright monomeric red fluorescent protein for cellular imaging

(2016) Daphne S Bindels et al.   NATURE METHODS

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells

(2016) L. Lei et al.   SCIENCE

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs

(2016) Michał Pasternak et al.   Open Biology

Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting

(2016) Bryce T. Bajar et al.   Scientific Reports

Mobilization of Dormant Cnot7 mRNA Promotes Deadenylation of Maternal Transcripts During Mouse Oocyte Maturation1

(2015) Jun Ma et al.   BIOLOGY OF REPRODUCTION

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes

(2015) Sybille Pfender et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

A NovelMitoTimerReporter Gene for Mitochondrial Content, Structure, Stress, and Damagein Vivo

(2014) Rhianna C. Laker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A stress assembly that confers cell viability by preserving ERES components during amino-acid starvation

(2014) Margarita Zacharogianni et al.   eLife

Zar1 represses translation in Xenopus oocytes and binds to the TCS in maternal mRNAs with different characteristics than Zar2

(2013) Tomomi M. Yamamoto et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

(2013) Bin Shen et al.   CELL RESEARCH

Optimization of Enrichment Conditions on TiO2 Chromatography Using Glycerol As an Additive Reagent for Effective Phosphoproteomic Analysis

(2013) Isao Fukuda et al.   JOURNAL OF PROTEOME RESEARCH

Localisation of RNAs into the Germ Plasm of Vitellogenic Xenopus Oocytes

(2013) Sarbjit Nijjar et al.   PLoS One

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice

(2012) Ozlem Guzeloglu-Kayisli et al.   BIOCHEMICAL JOURNAL

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Maternally Recruited DCP1A and DCP2 Contribute to Messenger RNA Degradation During Oocyte Maturation and Genome Activation in Mouse1

(2012) Jun Ma et al.   BIOLOGY OF REPRODUCTION

Fluorescence Fluctuation Spectroscopy Enables Quantitative Imaging of Single mRNAs in Living Cells

(2012) Bin Wu et al.   BIOPHYSICAL JOURNAL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Absence of MSY2 in Mouse Oocytes Perturbs Oocyte Growth and Maturation, RNA Stability, and the Transcriptome

(2011) S. Medvedev et al.   BIOLOGY OF REPRODUCTION

P-Body Loss Is Concomitant with Formation of a Messenger RNA Storage Domain in Mouse Oocytes1

(2010) Matyas Flemr et al.   BIOLOGY OF REPRODUCTION

Maternal control of early mouse development

(2010) L. Li et al.   DEVELOPMENT

Redistribution of mitochondria leads to bursts of ATP production during spontaneous mouse oocyte maturation

(2010) Yuansong Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

CDC2A (CDK1)-mediated phosphorylation of MSY2 triggers maternal mRNA degradation during mouse oocyte maturation

(2008) Sergey Medvedev et al.   DEVELOPMENTAL BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY