The ZAR1 protein in cancer; from epigenetic silencing to functional characterisation and epigenetic therapy of tumour suppressors
出版年份 2020 全文链接
标题
The ZAR1 protein in cancer; from epigenetic silencing to functional characterisation and epigenetic therapy of tumour suppressors
作者
关键词
ZAR1 zygote arrest 1, CpG island, Tumour suppressor, Cancer, Epigenetic therapy, Epigenetic editing, Promoter hypermethylation, Epigenetic inactivation, CRISPR-dCas, p53, Oocyte-embryo transition, mRNA binding, TCS translation control sequence, WEE
出版物
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Volume 1874, Issue 2, Pages 188417
出版商
Elsevier BV
发表日期
2020-08-21
DOI
10.1016/j.bbcan.2020.188417
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice
- (2020) Antje M. Richter et al. ONCOGENE
- Adeno-Associated Viral Vectors as a Tool for Large Gene Delivery to the Retina
- (2019) Trapani Genes
- Targeted Transgene Activation in the Brain Tissue by Systemic Delivery of Engineered AAV1 Expressing CRISPRa
- (2019) Cia-Hin Lau et al. Molecular Therapy-Nucleic Acids
- Structure‐function analysis of ZAR1 immune receptor reveals key molecular interactions for activity
- (2019) Maël Baudin et al. PLANT JOURNAL
- ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation
- (2019) Yan Rong et al. NUCLEIC ACIDS RESEARCH
- Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function
- (2019) Verena Deutschmeyer et al. Clinical Epigenetics
- RASSF10 Is a TGFβ-Target That Regulates ASPP2 and E-Cadherin Expression and Acts as Tumor Suppressor That Is Epigenetically Downregulated in Advanced Cancer
- (2019) Antje M. Richter et al. Cancers
- Delay in maternal transcript degradation in ovine embryos derived from low competence oocytes
- (2018) Laura Masala et al. MOLECULAR REPRODUCTION AND DEVELOPMENT
- Evaluation of bisulfite kits for DNA methylation profiling in terms of DNA fragmentation and DNA recovery using digital PCR
- (2018) Sam Kint et al. PLoS One
- The CRISPR tool kit for genome editing and beyond
- (2018) Mazhar Adli Nature Communications
- Novel Epigenetic Techniques Provided by the CRISPR/Cas9 System
- (2018) Nina Xie et al. Stem Cells International
- Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods
- (2018) J. Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- The Development of an AAV-Based CRISPR SaCas9 Genome Editing System That Can Be Delivered to Neurons in vivo and Regulated via Doxycycline and Cre-Recombinase
- (2018) Namrata Kumar et al. Frontiers in Molecular Neuroscience
- Strategies for analyzing bisulfite sequencing data
- (2017) Katarzyna Wreczycka et al. JOURNAL OF BIOTECHNOLOGY
- Cloning and expression analysis of zygote arrest 1 (Zar1) in New Zealand white rabbits
- (2017) DAN WANG et al. JOURNAL OF GENETICS
- ZAR1 knockdown promotes the differentiation of human neuroblastoma cells by suppression of MYCN expression
- (2017) Yosuke Watanabe et al. MEDICAL ONCOLOGY
- CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
- (2017) Tyler S Klann et al. NATURE BIOTECHNOLOGY
- Colorectal cancer screening: An updated review of the available options
- (2017) Iyad A Issa et al. WORLD JOURNAL OF GASTROENTEROLOGY
- ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer
- (2017) Antje M. Richter et al. Clinical Epigenetics
- Evaluation of DNA methylation in promoter regions of SFRP4 and ZAR1 in urine and plasma of women with cervical lesions
- (2017) Rene Hoffstetter et al. Translational Cancer Research
- Droplet Digital PCR versus qPCR for gene expression analysis with low abundant targets: from variable nonsense to publication quality data
- (2017) Sean C. Taylor et al. Scientific Reports
- Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing
- (2016) Angelo Amabile et al. CELL
- Translation repression by maternal RNA binding protein Zar1 is essential for early oogenesis in zebrafish
- (2016) Liyun Miao et al. DEVELOPMENT
- World Cancer Report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, WHO Press, 2015
- (2016) Shelley McGuire Advances in Nutrition
- The Arabidopsis Receptor Kinase ZAR1 Is Required for Zygote Asymmetric Division and Its Daughter Cell Fate
- (2016) Tian-Ying Yu et al. PLoS Genetics
- Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation
- (2016) James I. McDonald et al. Biology Open
- Aberrant Promoter Methylation of the Tumour Suppressor RASSF10 and Its Growth Inhibitory Function in Breast Cancer
- (2016) Antje Richter et al. Cancers
- Exhaled Breath Condensate: Technical and Diagnostic Aspects
- (2015) Efstathia M. Konstantinidi et al. TheScientificWorldJOURNAL
- Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics
- (2015) Alan Kirwan et al. Biomed Research International
- Exhaled Breath Condensate: Technical and Diagnostic Aspects
- (2015) Efstathia M. Konstantinidi et al. Scientific World Journal
- Pan-Cancer Analysis of Mutation Hotspots in Protein Domains
- (2015) Martin L. Miller et al. Cell Systems
- Evaluation ofZAR1andSFRP4methylation status as potentials biomarkers for diagnosis in cervical cancer: exploratory study phase I
- (2014) Priscilla Brebi et al. BIOMARKERS
- Developmental competence and gene expression of immature oocytes following liquid helium vitrification in bovine
- (2014) Jun-Yi Chen et al. CRYOBIOLOGY
- Identification of Frequent Differentially Methylated Region in Sporadic Bladder Cancers
- (2014) Ryo Hasegawa et al. UROLOGIA INTERNATIONALIS
- Zar1 represses translation in Xenopus oocytes and binds to the TCS in maternal mRNAs with different characteristics than Zar2
- (2013) Tomomi M. Yamamoto et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
- (2013) Albert W Cheng et al. CELL RESEARCH
- Non-promoter DNA hypermethylation of Zygote Arrest 1 (ZAR1) in neuroblastomas
- (2013) Kiminobu Sugito et al. JOURNAL OF PEDIATRIC SURGERY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Concise Drug Review: Azacitidine and Decitabine
- (2013) E. J. B. Derissen et al. ONCOLOGIST
- DNA hypermethylation of zygote arrest 1 (ZAR1) in hepatitis C virus positive related hepatocellular carcinoma
- (2013) Keiko Takagi et al. SpringerPlus
- Xenopus laevis zygote arrest 2 (zar2) encodes a zinc finger RNA-binding protein that binds to the translational control sequence in the maternal Wee1 mRNA and regulates translation
- (2012) Amanda Charlesworth et al. DEVELOPMENTAL BIOLOGY
- Impact of gonadotropin supplementation on the expression of germ cell marker genes (MATER, ZAR1, GDF9, and BMP15) during in vitro maturation of buffalo (Bubalus bubalis) oocyte
- (2012) Amar Nath et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- The tumor suppressor RASSF10 is upregulated upon contact inhibition and frequently epigenetically silenced in cancer
- (2012) A M Richter et al. Oncogenesis
- Structure and functions of powerful transactivators: VP16, MyoD and FoxA
- (2011) Hiroyuki Hirai et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- RASSF10 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin but Uncommon in Nevus Cell Nevi
- (2011) Peter Helmbold et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Identification and analysis of an early diagnostic marker for malignant melanoma: ZAR1 intra-genic differential methylation
- (2010) Yui Shinojima et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Cell cycle-dependent regulation of the bi-directional overlapping promoter of human BRCA2/ZAR2 genes in breast cancer cells
- (2010) Smita Misra et al. Molecular Cancer
- Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences
- (2010) Undraga Schagdarsurengin et al. Molecular Cancer
- Aberrant Hypermethylation of Non-Promoter Zygote Arrest 1 (Zar1) in Human Brain Tumors
- (2010) Takao WATANABE et al. NEUROLOGIA MEDICO-CHIRURGICA
- Expression of chicken zygote arrest 1 (Zar1) and Zar1-like genes during sexual maturation and embryogenesis
- (2010) Georgios Michailidis et al. VETERINARY RESEARCH COMMUNICATIONS
- Mouse ZAR1-like (XM_359149) colocalizes with mRNA processing components and its dominant-negative mutant caused two-cell-stage embryonic arrest
- (2009) Jianjun Hu et al. DEVELOPMENTAL DYNAMICS
- In silico identification and molecular characterization of genes predominantly expressed in the fish oocyte
- (2008) Julien Bobe et al. BMC GENOMICS
- A putative protein structurally related to zygote arrest 1 (Zar1), Zar1-like, is encoded by a novel gene conserved in the vertebrate lineage
- (2008) Lorenzo Sangiorgio et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
- A novel mRNA 3′ untranslated region translational control sequence regulates Xenopus Wee1 mRNA translation
- (2008) Yi Ying Wang et al. DEVELOPMENTAL BIOLOGY
- Inhaled Prostanoids in the Therapy of Pulmonary Hypertension
- (2008) Tobias Gessler et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Trends in the global funding and activity of cancer research
- (2008) Seth Eckhouse et al. Molecular Oncology
- Cis-acting elements (E-box and NBE) in the promoter region of three maternal genes (Histone H1oo, Nucleoplasmin 2, andZygote Arrest 1) are required for oocyte-specific gene expression in the mouse
- (2008) Kazunobu Tsunemoto et al. MOLECULAR REPRODUCTION AND DEVELOPMENT
- Expression pattern of zygote arrest 1 (ZAR1), maternal antigen that embryo requires (MATER), growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) genes in ovine oocytes andin vitro-produced preimplantation embryos
- (2008) Daniela Bebbere et al. REPRODUCTION FERTILITY AND DEVELOPMENT
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