Interferon beta attenuates recognition memory impairment and improves brain glucose uptake in a rat model of Alzheimer's disease: Involvement of mitochondrial biogenesis and PI3K pathway
出版年份 2022 全文链接
标题
Interferon beta attenuates recognition memory impairment and improves brain glucose uptake in a rat model of Alzheimer's disease: Involvement of mitochondrial biogenesis and PI3K pathway
作者
关键词
-
出版物
NEUROPEPTIDES
Volume 95, Issue -, Pages 102262
出版商
Elsevier BV
发表日期
2022-06-03
DOI
10.1016/j.npep.2022.102262
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Glucose Metabolic Dysfunction in Neurodegenerative Diseases—New Mechanistic Insights and the Potential of Hypoxia as a Prospective Therapy Targeting Metabolic Reprogramming
- (2021) Rongrong Han et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial biogenesis: An update
- (2020) Lucia‐Doina Popov JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism
- (2020) Sergio Rius-Pérez et al. Oxidative Medicine and Cellular Longevity
- Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours
- (2020) Fei Xu et al. Cell and Bioscience
- Regional disconnection in Alzheimer dementia and amyloid positive MCI: Association of EEG functional connectivity and brain glucose metabolism
- (2020) Una Smailovic et al. Brain Connectivity
- Comprehensive Review on Alzheimer’s Disease: Causes and Treatment
- (2020) Zeinab Breijyeh et al. MOLECULES
- Prestimulation of Microglia Through TLR4 Pathway Promotes Interferon Beta Expression in a Rat Model of Alzheimer’s Disease
- (2019) Niloufar Yousefi et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer’s disease
- (2019) Giuseppa Mudò et al. Journal of Neuroinflammation
- Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimer's disease: Modulation of hippocampal neurogenesis and apoptosis as underlying mechanism
- (2019) Sara Chavoshinezhad et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Imaging and Spectral Characteristics of Amyloid Plaque Autofluorescence in Brain Slices from the APP/PS1 Mouse Model of Alzheimer’s Disease
- (2019) Yunling Gao et al. Neuroscience Bulletin
- Intranasal interferon beta improves memory and modulates inflammatory responses in a mutant APP-overexpressing rat model of Alzheimer’s disease
- (2019) Sara Chavoshinezhad et al. BRAIN RESEARCH BULLETIN
- NEMA NU‐4 2008 performance evaluation of Xtrim‐PET: A prototype SiPM‐based preclinical scanner
- (2019) Mahsa Amirrashedi et al. MEDICAL PHYSICS
- Altered Insulin Signaling in Alzheimer’s Disease Brain – Special Emphasis on PI3K-Akt Pathway
- (2019) Sami Gabbouj et al. Frontiers in Neuroscience
- Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
- (2018) Fuyuki Kametani et al. Frontiers in Neuroscience
- Triggering microglia through toll-like receptor 2 pathway induced interferon β expression in cell and animal model of Alzheimer’s disease
- (2018) Nooshin Heshmati-Fakhr et al. NEUROREPORT
- Non-motor Behavioral Alterations of PGC-1α-Deficient Mice – A Peculiar Phenotype With Slight Male Preponderance and No Apparent Progression
- (2018) Levente Szalardy et al. Frontiers in Behavioral Neuroscience
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions
- (2018) Karina Sánchez-Alegría et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer’s disease Neurons
- (2017) Ravi Rajmohan et al. JOURNAL OF ALZHEIMERS DISEASE
- Amelioration of Experimental Autoimmune Encephalomyelitis in Mice by Interferon-Beta Gene Therapy, Using a Long-Term Expression Plasmid Vector
- (2017) Atsushi Hamana et al. MOLECULAR PHARMACEUTICS
- Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by β-Amyloid in Rats
- (2017) Nutchareeporn Nillert et al. Nutrients
- Behavioral Changes and Hippocampus Glucose Metabolism in APP/PS1 Transgenic Mice via Electro-acupuncture at Governor Vessel Acupoints
- (2017) Jin Cao et al. Frontiers in Aging Neuroscience
- The innovative development in interferon beta treatments of relapsing-remitting multiple sclerosis
- (2017) Claus Madsen Brain and Behavior
- Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer’s disease
- (2017) Valentine Hamm et al. Science Advances
- IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury
- (2017) Victoria E. Thaney et al. Scientific Reports
- Intranasal Administration of Interferon Beta Attenuates Neuronal Apoptosis via the JAK1/STAT3/BCL-2 Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy
- (2016) Brandon J. Dixon et al. ASN Neuro
- The Emerging Therapeutic Role of NGF in Alzheimer’s Disease
- (2016) Chao-Jin Xu et al. NEUROCHEMICAL RESEARCH
- Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS
- (2016) Line S. Reinert et al. Nature Communications
- Nerve growth factor-induced Akt/mTOR activation protects the ischemic heart via restoring autophagic flux and attenuating ubiquitinated protein accumulation
- (2016) Zhou-Guang Wang et al. Oncotarget
- Interferon‐β Modulates Inflammatory Response in Cerebral Ischemia
- (2016) Ping‐Chang Kuo et al. Journal of the American Heart Association
- Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson’s Disease-like Dementia
- (2015) Patrick Ejlerskov et al. CELL
- Balancing mitochondrial biogenesis and mitophagy to maintain energy metabolism homeostasis
- (2015) K Palikaras et al. CELL DEATH AND DIFFERENTIATION
- Staging of cognitive deficits and neuropathological and ultrastructural changes in streptozotocin-induced rat model of Alzheimer’s disease
- (2015) Ana Knezovic et al. JOURNAL OF NEURAL TRANSMISSION
- Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain
- (2015) Cathleen Pfefferkorn et al. JOURNAL OF VIROLOGY
- Interferon beta (IFN-β) treatment exerts potential neuroprotective effects through neurotrophic factors and novel neurotensin/neurotensin high affinity receptor 1 pathway
- (2015) Yang Mao-Draayer et al. Neural Regeneration Research
- A novel rat model of Alzheimer’s disease based on lentiviral-mediated expression of mutant APP
- (2015) S. Parsi et al. NEUROSCIENCE
- Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks
- (2014) King-Hwa Ling et al. BMC GENOMICS
- Sex differences in mitochondrial biogenesis determine neuronal death and survival in response to oxygen glucose deprivation and reoxygenation
- (2014) Jaswinder Sharma et al. BMC NEUROSCIENCE
- Nerve Growth Factor (NGF) Regulates Activity of Nuclear Factor of Activated T-cells (NFAT) in Neurons via the Phosphatidylinositol 3-Kinase (PI3K)-Akt-Glycogen Synthase Kinase 3β (GSK3β) Pathway
- (2014) Man-Su Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of interferon-beta on neural stem cells and in a mouse model of multiple sclerosis
- (2014) Sarah Stahlke et al. JOURNAL OF NEUROIMMUNOLOGY
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- PGC-1 Provides a Transcriptional Framework for Synchronous Neurotransmitter Release from Parvalbumin-Positive Interneurons
- (2014) E. K. Lucas et al. JOURNAL OF NEUROSCIENCE
- Beta Interferon Regulation of Glucose Metabolism Is PI3K/Akt Dependent and Important for Antiviral Activity against Coxsackievirus B3
- (2014) J. D. Burke et al. JOURNAL OF VIROLOGY
- Interferon beta induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice
- (2013) Alice Chort et al. BRAIN
- PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease
- (2013) Cora O' Neill EXPERIMENTAL GERONTOLOGY
- Toll-like receptor 3 activation modulates hippocampal network excitability, via glial production of interferon-β
- (2013) Derek A. Costello et al. HIPPOCAMPUS
- PD-L1 Expression by Neurons Nearby Tumors Indicates Better Prognosis in Glioblastoma Patients
- (2013) Y. Liu et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease
- (2013) Amanda L. Wright et al. PLoS One
- Subcutaneous Interferon β-1a May Protect against Cognitive Impairment in Patients with Relapsing–Remitting Multiple Sclerosis: 5-Year Follow-up of the COGIMUS Study
- (2013) Francesco Patti et al. PLoS One
- PI3K/Akt Signal Pathway Involved in the Cognitive Impairment Caused by Chronic Cerebral Hypoperfusion in Rats
- (2013) Yi Shu et al. PLoS One
- Mitochondria impact brain function and cognition
- (2013) M. Picard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Presynaptic mitochondrial morphology in monkey prefrontal cortex correlates with working memory and is improved with estrogen treatment
- (2013) Y. Hara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies
- (2013) Zhichun Chen et al. PROGRESS IN NEUROBIOLOGY
- Sugar for the brain: the role of glucose in physiological and pathological brain function
- (2013) Philipp Mergenthaler et al. TRENDS IN NEUROSCIENCES
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- Relationship between imaging biomarkers, age, progression and symptom severity in Alzheimer's disease
- (2013) Juergen Dukart et al. NeuroImage-Clinical
- Interferon-β Delivery via Human Neural Stem Cell Abates Glial Scar Formation in Spinal Cord Injury
- (2012) Yusuke Nishimura et al. CELL TRANSPLANTATION
- An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
- (2012) Theresa R. Bomfim et al. JOURNAL OF CLINICAL INVESTIGATION
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Preplaque (Preclinical) Aß-Induced Inflammation and Nerve Growth Factor Deregulation in Transgenic Models of Alzheimers Disease-Like Amyloid Pathology
- (2012) A.C. Cuello et al. Neurodegenerative Diseases
- Activating mitochondrial regulator PGC-1α expression by astrocytic NGF is a therapeutic strategy for Huntington's disease
- (2012) Li-Wen Chen et al. NEUROPHARMACOLOGY
- NGF, Brain and Behavioral Plasticity
- (2012) Alessandra Berry et al. NEURAL PLASTICITY
- Imaging of microglia in patients with neurodegenerative disorders
- (2012) Marios Politis Frontiers in Pharmacology
- Amyloid Precursor Protein Processing and Alzheimer's Disease
- (2011) Richard J. O'Brien et al. Annual Review of Neuroscience
- Interferon β-1b directly modulates human neural stem/progenitor cell fate
- (2011) W. Tristram Arscott et al. BRAIN RESEARCH
- Direct Effects of Type I Interferons on Cells of the Immune System
- (2011) S. Hervas-Stubbs et al. CLINICAL CANCER RESEARCH
- β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia
- (2011) Robert Tamayev et al. EMBO Molecular Medicine
- Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
- (2011) Ying Liu et al. JOURNAL OF PATHOLOGY
- Mitochondria and Neuroplasticity
- (2010) Aiwu Cheng et al. ASN Neuro
- CREB: a multifaceted regulator of neuronal plasticity and protection
- (2010) Kensuke Sakamoto et al. JOURNAL OF NEUROCHEMISTRY
- Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease
- (2010) Dimitrios Kapogiannis et al. LANCET NEUROLOGY
- Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities
- (2009) William I. Sivitz et al. ANTIOXIDANTS & REDOX SIGNALING
- The effect of interferon-β on mouse neural progenitor cell survival and differentiation
- (2009) Marek Hirsch et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of neuron mitochondrial biogenesis and relevance to brain health
- (2009) Isaac G. Onyango et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Amyloid β-Induced Nerve Growth Factor Dysmetabolism in Alzheimer Disease
- (2009) Martin A. Bruno et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Intranasal delivery to the central nervous system: Mechanisms and experimental considerations
- (2009) Shyeilla V. Dhuria et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial
- (2009) Ludwig Kappos et al. LANCET NEUROLOGY
- The Insulin/Akt Signaling Pathway Is Targeted by Intracellular β-Amyloid
- (2009) Han-Kyu Lee et al. MOLECULAR BIOLOGY OF THE CELL
- Effects of immunomodulatory treatment with subcutaneous interferon beta-1a oncognitive decline in mildly disabled patients with relapsing—remitting multiple sclerosis
- (2009) F. Patti et al. Multiple Sclerosis Journal
- Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
- (2009) K. Ghosal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice
- (2008) Dick Terwel et al. AMERICAN JOURNAL OF PATHOLOGY
- Role of Mitochondrial Dysfunction in Insulin Resistance
- (2008) Jeong-a Kim et al. CIRCULATION RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now