PI3K/Akt Signal Pathway Involved in the Cognitive Impairment Caused by Chronic Cerebral Hypoperfusion in Rats

An enriched environment elevates corticosteroid receptor levels in the hippocampus and restores cognitive function in a rat model of chronic cerebral hypoperfusion

(2013) Lei Zhang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Environmental Enrichment Influences BDNF and NR1 Levels in the Hippocampus and Restores Cognitive Impairment in Chronic Cerebral Hypoperfused Rats

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Decreased Cerebral Perfusion and Oxidative Stress Result in Acute and Delayed Cognitive Impairment

(2012) Hui Liu et al.   CURRENT NEUROVASCULAR RESEARCH

Down-regulation of IGF-1/IGF-1R in hippocampus of rats with vascular dementia

(2012) Xiuqun Gong et al.   NEUROSCIENCE LETTERS

An enriched environment reverses the synaptic plasticity deficit induced by chronic cerebral hypoperfusion

(2011) Hong Zhu et al.   NEUROSCIENCE LETTERS

PI3 kinase signaling is involved in A -induced memory loss in Drosophila

(2010) H.-C. Chiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoflurane Posttreatment Reduces Neonatal Hypoxic–Ischemic Brain Injury in Rats by the Sphingosine-1-Phosphate/Phosphatidylinositol-3-Kinase/Akt Pathway

(2010) Yilin Zhou et al.   STROKE

Characteristic response of astrocytes to plasminogen/plasmin to upregulate transforming growth factor beta 3 (TGFβ3) production/secretion through proteinase-activated receptor-1 (PAR-1) and the downstream phosphatidylinositol 3-kinase (PI3K)-Akt/PKB signaling cascade

(2009) Shyuichi Maeda et al.   BRAIN RESEARCH

The role of phosphoinositide-3-kinase/Akt pathway in propofol-induced postconditioning against focal cerebral ischemia-reperfusion injury in rats

(2009) Hai-yun Wang et al.   BRAIN RESEARCH

Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration

(2009) J. Simon Lunn et al.   Developmental Neurobiology

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of ceramide-induced neuronal death: Cell metabolism meets neurodegeneration

(2008) Gonzalo Arboleda et al.   BRAIN RESEARCH REVIEWS

Angelica Injection Reduces Cognitive Impairment during Chronic Cerebral Hypoperfusion through Brain-Derived Neurotrophic Factor and Nerve Growth Factor

(2008) Junjian Zhang et al.   CURRENT NEUROVASCULAR RESEARCH

The Akt signaling pathway contributes to postconditioning’s protection against stroke; the protection is associated with the MAPK and PKC pathways

(2008) Xuwen Gao et al.   JOURNAL OF NEUROCHEMISTRY

Detection of changed regional cerebral blood flow in mild cognitive impairment and early Alzheimer's dementia by perfusion-weighted magnetic resonance imaging

(2008) Christian Luckhaus et al.   NEUROIMAGE