Cooperative Catalyst‐Enabled Regio‐ and Stereodivergent Synthesis of α‐Quaternary α‐Amino Acids via Asymmetric Allylic Alkylation of Aldimine Esters with Racemic Allylic Alcohols

Catalytic Asymmetric Benzylation of Azomethine Ylides Enabled by Synergistic Lewis Acid/Palladium Catalysis

(2022) Xin Chang et al.   ORGANIC LETTERS

Stereodivergent propargylic alkylation of enals via cooperative NHC and copper catalysis

(2022) Yu-Hua Wen et al.   Nature Communications

Stereodivergent total synthesis of rocaglaol initiated by synergistic dual-metal-catalyzed asymmetric allylation of benzofuran-3(2H)-one

(2022) Yang Xu et al.   Chem

Stereodivergent Construction of 1,4‐Nonadjacent Stereocenters via Hydroalkylation of Racemic Allylic Alcohols Enabled by Copper/Ruthenium Relay Catalysis

(2022) Xin Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Catalysis between a Dipeptide Phosphonium Salt and a Metal‐Based Lewis Acid for Asymmetric Synthesis of N ‐Bridged [3.2.1] Ring Systems

(2022) Yuan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-catalyzed Z-retentive asymmetric allylic substitution reactions

(2021) Ru Jiang et al.   SCIENCE

Synergistic Ir/Cu Catalysis for Asymmetric Allylic Alkylation of Oxindoles: Enantio‐ and Diastereoselective Construction of Quaternary and Tertiary Stereocenters

(2021) Tianhong Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

One Stone Two Birds – Enantioselective Bimetalic Catalysis for α‐Amino Acid Derivatives with An Allene Unit

(2021) Junzhe Xiao et al.   CHINESE JOURNAL OF CHEMISTRY

Stereodivergent Synthesis of Tertiary Fluoride-Tethered Allenes via Copper and Palladium Dual Catalysis

(2021) Shao-Qian Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantio‐ and Diastereodivergent Synthesis of Spirocycles through Dual‐Metal‐Catalyzed [3+2] Annulation of 2‐Vinyloxiranes with Nucleophilic Dipoles

(2021) Youbin Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis

(2021) Jiacheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Pd/Amine-Catalyzed Stereodivergent Hydroalkylation of 1,3-Dienes with Aldehydes: Reaction Development, Mechanism, and Stereochemical Origins

(2021) Hongfa Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Pd/Cu Catalysis for Asymmetric Desymmetric Alkylation of Allylic Geminal Dicarboxylates

(2021) Xiaohong Huo et al.   CCS Chemistry

Palladium-Catalyzed Asymmetric Allylic Alkylation/α-Iminol Rearrangement: A Facile Access to 2-Spirocyclic-Indoline Derivatives

(2021) Xin Chang et al.   CCS Chemistry

Stereodivergent Synthesis of Enantioenriched γ‐Butyrolactones Bearing Two Vicinal Stereocenters Enabled by Synergistic Copper and Iridium Catalysis

(2021) Lu Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium Catalyzed Enantioselective Intermolecular Indole C2-Allylation

(2020) James A. Rossi-Ashton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Reactions with N-Metallated Azomethine Ylides

(2020) Liang Wei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates

(2020) Rui He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Catalysis with Azomethine Ylides

(2020) Liang Wei et al.   CHINESE JOURNAL OF CHEMISTRY

Stereodivergent Synthesis of α-Quaternary Serine and Cysteine Derivatives Containing Two Contiguous Stereogenic Centers via Synergistic Cu/Ir Catalysis

(2020) Hui-Min Wu et al.   ORGANIC LETTERS

Diastereodivergent Synthesis of β‐Amino Alcohols through Dual‐Metal‐Catalyzed Coupling of Alkoxyallenes with Aldimine Esters

(2020) Weiwei Zi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Dual Transition Metal Catalysis

(2020) U Bin Kim et al.   CHEMICAL REVIEWS

Stereodivergent Carbon–Carbon Bond Formation between Iminium and Enolate Intermediates by Synergistic Organocatalysis

(2020) Byungjun Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Cu/Pd Catalyzed Asymmetric Allenylic Alkylation of Azomethine Ylides for the Construction of α‐Allenylic Substituted Nonproteinogenic α‐Amino Acids

(2019) Chun-Jiang Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iridium-Catalyzed Asymmetric Synthesis of Functionally Rich Molecules Enabled by (Phosphoramidite,Olefin) Ligands

(2019) Simon L. Rössler et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stereodivergent Construction of Tertiary Fluorides in Vicinal Stereogenic Pairs by Allylic Substitution with Iridium and Copper Catalysts

(2019) Zhi-Tao He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic catalysis for cascade allylation and 2-aza-cope rearrangement of azomethine ylides

(2019) Liang Wei et al.   Nature Communications

Synergetic iridium and amine catalysis enables asymmetric [4+2] cycloadditions of vinyl aminoalcohols with carbonyls

(2019) Mao-Mao Zhang et al.   Nature Communications

Stereodivergent Coupling of 1,3-Dienes with Aldimine Esters Enabled by Synergistic Pd and Cu Catalysis

(2019) Qinglong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Pd/Cu Catalysis in Organic Synthesis

(2019) Yue Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereodivergent assembly of tetrahydro-γ-carbolines via synergistic catalytic asymmetric cascade reaction

(2019) Shi-Ming Xu et al.   Nature Communications

Diastereodivergent synthesis of enantioenriched α,β-disubstituted γ-butyrolactones via cooperative N-heterocyclic carbene and Ir catalysis

(2019) Santanu Singha et al.   Nature Catalysis

Enantioselective Synthesis of Vicinal All-Carbon Quaternary Centers via Iridium-Catalyzed Allylic Alkylation

(2018) J. Caleb Hethcox et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd/Cu dual catalysis: highly enantioselective access to α-substituted α-amino acids and α-amino amides

(2018) Xiaohong Huo et al.   CHEMICAL COMMUNICATIONS

Stereodivergent Catalysis

(2018) Irina P. Beletskaya et al.   CHEMICAL REVIEWS

Stereodivergent Synthesis of α,α-Disubstituted α-Amino Acids via Synergistic Cu/Ir Catalysis

(2018) Liang Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylation of Azaaryl Acetamides and Acetates by Synergistic Iridium and Copper Catalysis

(2018) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing Vicinal Stereocenters

(2018) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and Enantioselective Rhodium-Catalyzed Allylic Alkylation of Racemic Allylic Alcohols with 1,3-Diketones

(2018) Sheng-Biao Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic asymmetric construction of spiropyrrolidines via 1,3-dipolar cycloaddition of azomethine ylides

(2018) Xin Fang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synergistic Cu/Pd Catalysis for Enantioselective Allylation of Ketimine Esters: The Direct Synthesis of α-Substituted α-Amino Acids and 2H- Pyrrols

(2018) Liang Wei et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective and Diastereodivergent Access to α-Substituted α-Amino Acids via Dual Iridium and Copper Catalysis

(2018) Jiacheng Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Iridium-Catalyzed Asymmetric Allylic Substitution Reactions

(2018) Qiang Cheng et al.   CHEMICAL REVIEWS

Stereoselective Allylic Alkylation of 1-Pyrroline-5-carboxylic Esters via a Pd/Cu Dual Catalysis

(2018) Penglin Liu et al.   ORGANIC LETTERS

Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis

(2017) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Coupling of Aldehydes and Alkynes via Synergistic Catalysis Using Rh and Jacobsen’s Amine

(2017) Faben A. Cruz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergence in Asymmetric Catalysis

(2017) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones

(2016) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylic Substitutions with Aryl Acetic Acid Esters by Synergistic Iridium and Lewis Base Catalysis

(2016) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Primary Amine/Palladium Dual Catalysis for Asymmetric Allylic Alkylation of β-Ketocarbonyl Compounds with Allylic Alcohols

(2015) Han Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes

(2015) Tobias Sandmeier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric γ-Allylation of α,β-Unsaturated Aldehydes by Combined Organocatalysis and Transition-Metal Catalysis

(2015) Line Naesborg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition metal-catalyzed allylic substitution reactions with unactivated allylic substrates

(2015) Nicholas A. Butt et al.   CHEMICAL SOCIETY REVIEWS

Cu(i)/TF-BiphamPhos-catalyzed asymmetric Michael addition of cyclic ketimino esters to alkylidene malonates

(2015) Zhi-Yong Xue et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective cooperative catalysis

(2015) Suleman M. Inamdar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Organocatalysis Combined with Metal Catalysis: Concept, Proof of Concept, and Beyond

(2014) Dian-Feng Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cooperative Catalysis by Palladium and a Chiral Phosphoric Acid: Enantioselective Amination of Racemic Allylic Alcohols

(2014) Debasis Banerjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–H Functionalization in the Synthesis of Amino Acids and Peptides

(2014) Anaïs F. M. Noisier et al.   CHEMICAL REVIEWS

Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis

(2014) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted Acid Accelerated Pd-Catalyzed Direct Asymmetric Allylic Alkylation of Azlactones with Simple Allylic Alcohols: A Practical Access to Quaternary Allylic Amino Acid Derivatives

(2014) Hui Zhou et al.   ORGANIC LETTERS

Pd-Catalyzed Asymmetric Allylic Alkylation of Pyrazol-5-ones with Allylic Alcohols: The Role of the Chiral Phosphoric Acid in C–O Bond Cleavage and Stereocontrol

(2013) Zhong-Lin Tao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir-catalyzed intermolecular asymmetric allylic dearomatization reaction of indoles

(2013) Xiao Zhang et al.   Chemical Science

Combining transition metal catalysis and organocatalysis – an update

(2012) Zhenting Du et al.   CHEMICAL SOCIETY REVIEWS

Catalytic Asymmetric Construction of Spiro(γ-butyrolactam-γ-butyrolactone) Moieties through Sequential Reactions of Cyclic Imino Esters with Morita-Baylis-Hillman Bromides

(2012) Huai-Long Teng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Benzylic Phosphates as Electrophiles in the Palladium-Catalyzed Asymmetric Benzylation of Azlactones

(2012) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Asymmetric α-Allylation of Aldehydes with Simple Allylic Alcohols Enabled by the Concerted Action of Three Different Catalysts

(2011) Gaoxi Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition Metal-Catalyzed Decarboxylative Allylation and Benzylation Reactions

(2011) Jimmie D. Weaver et al.   CHEMICAL REVIEWS

A Facile Cu(I)/TF-BiphamPhos-Catalyzed Asymmetric Approach to Unnatural α-Amino Acid Derivatives Containinggem-Bisphosphonates

(2011) Zhi-Yong Xue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Facile Cu(I)/BINAP-Catalyzed Asymmetric Approach to Functionalized Pyroglutamate Derivatives Bearing a Unique Quaternary Stereogenic Center

(2011) Huai-Long Teng et al.   ORGANIC LETTERS

Binaphthyl-Modified Quaternary Phosphonium Salts as Chiral Phase-Transfer Catalysts: Asymmetric Amination of β-Keto Esters

(2008) Rongjun He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH

Metal-Catalyzed Enantioselective Allylation in Asymmetric Synthesis

(2007) Zhan Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION