Synergetic iridium and amine catalysis enables asymmetric [4+2] cycloadditions of vinyl aminoalcohols with carbonyls

Non-Bonding Interactions Enable the Selective Formation of Branched Products in Palladium-Catalyzed Allylic Substitution Reactions

(2018) Ya-Ni Wang et al.   Chemistry-An Asian Journal

Stereodivergent Synthesis of α,α-Disubstituted α-Amino Acids via Synergistic Cu/Ir Catalysis

(2018) Liang Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective [5 + 2] Annulations through Cooperative N-Heterocyclic Carbene (NHC) Organocatalysis and Palladium Catalysis

(2018) Santanu Singha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylation of Azaaryl Acetamides and Acetates by Synergistic Iridium and Copper Catalysis

(2018) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing Vicinal Stereocenters

(2018) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-metal-catalyzed cyclization reactions using vinyl and ethynyl benzoxazinones as dipole precursors

(2018) Tian-Ren Li et al.   TETRAHEDRON LETTERS

Iridium-Catalyzed Highly Regioselective and Diastereoselective Allylic Etherification To Access cis-2,6-Disubstituted Dihydropyridinones

(2018) Wangze Song et al.   JOURNAL OF ORGANIC CHEMISTRY

Sequential Visible-Light Photoactivation and Palladium Catalysis Enabling Enantioselective [4+2] Cycloadditions

(2017) Miao-Miao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies on a Cooperative NHC Organocatalysis/Palladium Catalysis System: Uncovering Significant Lessons for Mixed Chiral Pd(NHC)(PR3) Catalyst Design

(2017) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir-Catalyzed Asymmetric Total Synthesis of (−)-Communesin F

(2017) Xiao Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergence in Asymmetric Catalysis

(2017) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Construction of the Tryptanthrin Skeleton via an Enantioselective Decarboxylative [4 + 2] Cyclization

(2017) Guang-Jian Mei et al.   ORGANIC LETTERS

Recent Advances in the Catalytic Cycloaddition of 1,n-Dipoles

(2017) Nirupam De et al.   ACS Catalysis

P,S Ligands for the Asymmetric Construction of Quaternary Stereocenters in Palladium-Catalyzed Decarboxylative [4+2] Cycloadditions

(2016) Yi Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron-Catalyzed Decarboxylative (4+1) Cycloadditions: Exploiting the Reactivity of Ambident Iron-Stabilized Intermediates

(2016) Qiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Decarboxylative [4+2] Cycloaddition by Synergistic Palladium and Organocatalysis

(2016) Lars A. Leth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones

(2016) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations

(2016) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylic Substitutions with Aryl Acetic Acid Esters by Synergistic Iridium and Lewis Base Catalysis

(2016) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric [4 + 1] Annulation of Sulfur Ylides with Copper–Allenylidene Intermediates

(2016) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Inverse-Electron-Demand Oxa-Diels–Alder Reaction of Allylic Ketones through Dienamine Catalysis

(2016) Ming-Lin Shi et al.   ORGANIC LETTERS

Pushing the Limits of Aminocatalysis: Enantioselective Transformations of α-Branched β-Ketocarbonyls and Vinyl Ketones by Chiral Primary Amines

(2015) Long Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules

(2015) Yiyang Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric γ-Allylation of α,β-Unsaturated Aldehydes by Combined Organocatalysis and Transition-Metal Catalysis

(2015) Line Naesborg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The [3 + 3]-Cycloaddition Alternative for Heterocycle Syntheses: Catalytically Generated Metalloenolcarbenes as Dipolar Adducts

(2014) Xinfang Xu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transition-Metal-Catalyzed Asymmetric Allylic Dearomatization Reactions

(2014) Chun-Xiang Zhuo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Access to Oxoquinoline Heterocycles by N-Heterocyclic Carbene Catalyzed Ester Activation for Selective Reaction with an Enone

(2014) Zhenqian Fu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Counteranion Strategy for Asymmetric Oxidative C(sp3)H/C(sp3)H Coupling: Enantioselective α-Allylation of Aldehydes with Terminal Alkenes

(2014) Pu-Sheng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Decarboxylative Cycloaddition of Vinylethylene Carbonates with Formaldehyde: Enantioselective Construction of Tertiary Vinylglycols

(2014) Ajmal Khan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis

(2014) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic enantioselective synthesis of quaternary carbon stereocentres

(2014) Kyle W. Quasdorf et al.   NATURE

Asymmetric Direct Vinylogous Michael Additions of Allyl Alkyl Ketones to Maleimides through Dienamine Catalysis

(2014) Gu Zhan et al.   ORGANIC LETTERS

Asymmetric trapping of zwitterionic intermediates by sulphur ylides in a palladium-catalysed decarboxylation-cycloaddition sequence

(2014) Tian-Ren Li et al.   Nature Communications

Direct Asymmetric Vinylogous Aldol Reaction of Allyl Ketones with Isatins: Divergent Synthesis of 3-Hydroxy-2-Oxindole Derivatives

(2013) Bo Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Asymmetric α-Allylation of α-Branched Aldehydes by Two Catalytic Systems with an Achiral Pd Complex and a Chiral Primary α-Amino Acid

(2013) Masanori Yoshida et al.   JOURNAL OF ORGANIC CHEMISTRY

Ligand-enabled multiple absolute stereocontrol in metal-catalysed cycloaddition for construction of contiguous all-carbon quaternary stereocentres

(2013) Kohsuke Ohmatsu et al.   Nature Chemistry

Enantio- and Diastereodivergent Dual Catalysis:  -Allylation of Branched Aldehydes

(2013) S. Krautwald et al.   SCIENCE

Aminocatalytic Asymmetric Diels–Alder Reactions via HOMO Activation

(2012) Jun-Long Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

An Organocatalytic Cascade Approach toward Polysubstituted Quinolines and Chiral 1,4-Dihydroquinolines-Unanticipated Effect of N-Protecting Groups

(2012) Xinshuai Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies

(2012) Wen-Bo Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Mediated Annulation of Vinyl Aziridines with Michael Acceptors: Stereocontrolled Synthesis of Substituted Pyrrolidines and Its Application in a Formal Synthesis of (−)-α-Kainic Acid

(2011) Martin A. Lowe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Guiding the nitrogen nucleophile to the middle: palladium-catalyzed decarboxylative cyclopropanation of 2-alkylidenetrimethylene carbonates with isocyanates

(2011) Ryo Shintani et al.   CHEMICAL COMMUNICATIONS

Transition Metal-Catalyzed Decarboxylative Allylation and Benzylation Reactions

(2011) Jimmie D. Weaver et al.   CHEMICAL REVIEWS

Advances in the Chemistry of Tetrahydroquinolines

(2011) Vellaisamy Sridharan et al.   CHEMICAL REVIEWS

Mechanistically Driven Development of Iridium Catalysts for Asymmetric Allylic Substitution

(2010) John F. Hartwig et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Cycloadditions of Palladium-Polarized Aza-o-xylylenes

(2008) Chao Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Catalyzed Enantioselective Allylation in Asymmetric Synthesis

(2007) Zhan Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION