Echinacoside Improves Cognitive Impairment by Inhibiting Aβ Deposition Through the PI3K/AKT/Nrf2/PPARγ Signaling Pathways in APP/PS1 Mice

Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer’s Disease Model Mice

(2020) Akira Uruno et al.   MOLECULAR AND CELLULAR BIOLOGY

Crosstalk between ER stress, NLRP3 inflammasome, and inflammation

(2020) Wei Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Nrf2 Ablation Promotes Alzheimer’s Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress

(2020) Peng Ren et al.   Oxidative Medicine and Cellular Longevity

gp91phox, a Novel Biomarker Evaluating Oxidative Stress, Is Elevated in Subclinical Hypothyroidism

(2020) Xiaochun Ma et al.   International Journal of Endocrinology

Nrf2: a dark horse in Alzheimer's disease treatment

(2020) Alsiddig Osama et al.   AGEING RESEARCH REVIEWS

Echinacoside Suppresses Amyloidogenesis and Modulates F-actin Remodeling by Targeting the ER Stress Sensor PERK in a Mouse Model of Alzheimer’s Disease

(2020) Yuan Dai et al.   Frontiers in Cell and Developmental Biology

Therapeutic Approaches to Alzheimer’s Disease Through Modulation of NRF2

(2019) Gahee Bahn et al.   NEUROMOLECULAR MEDICINE

Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson’s Disease

(2019) Yan Liang et al.   Biomed Research International

Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis

(2019) Wei Wei et al.   NEUROCHEMICAL RESEARCH

Neuro-inflammation and anti-inflammatory treatment options for Alzheimer's disease

(2019) Tomris Ozben et al.   CLINICAL BIOCHEMISTRY

Txnip mediates glucocorticoid-activated NLRP3 inflammatory signaling in mouse microglia

(2019) Veni Bharti et al.   NEUROCHEMISTRY INTERNATIONAL

Age related neurodegenerative Alzheimer’s disease: Usage of traditional herbs in therapeutics

(2019) Abhishek Singh et al.   NEUROSCIENCE LETTERS

Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway

(2019) Yu Zhuang et al.   Oxidative Medicine and Cellular Longevity

Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis

(2018) Chun-Yan Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury

(2018) Yanghao Hou et al.   BEHAVIOURAL BRAIN RESEARCH

Echinacoside alleviated LPS-induced cell apoptosis and inflammation in rat intestine epithelial cells by inhibiting the mTOR/STAT3 pathway

(2018) Lei Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Echinacoside, an Inestimable Natural Product in Treatment of Neurological and other Disorders

(2018) Jingjing Liu et al.   MOLECULES

6′-O-Galloylpaeoniflorin Attenuates Cerebral Ischemia Reperfusion-Induced Neuroinflammation and Oxidative Stress via PI3K/Akt/Nrf2 Activation

(2018) Zhongmei Wen et al.   Oxidative Medicine and Cellular Longevity

Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease

(2018) Estella A. Newcombe et al.   Journal of Neuroinflammation

Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway

(2018) Mu Zhang et al.   Theranostics

Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

(2018) Shaonan Hu et al.   MOLECULES

Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer’s disease

(2017) Caterina Branca et al.   HUMAN MOLECULAR GENETICS

Echinacoside's nigrostriatal dopaminergic protection against 6-OHDA-Induced endoplasmic reticulum stress through reducing the accumulation of Seipin

(2017) Yajie Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer’s Disease

(2017) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Echinacoside ameliorates the memory impairment and cholinergic deficit induced by amyloid beta peptides via the inhibition of amyloid deposition and toxicology

(2017) Young-Ji Shiao et al.   Food & Function

Ginsenoside Re reduces Aβ production by activating PPARγ to inhibit BACE1 in N2a/APP695 cells

(2016) Guoqiong Cao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nrf2—a therapeutic target for the treatment of neurodegenerative diseases

(2015) Delinda A. Johnson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tripchlorolide Attenuates β-amyloid Generation via Suppressing PPARγ-Regulated BACE1 Activity in N2a/APP695 Cells

(2015) Nan Lin et al.   MOLECULAR NEUROBIOLOGY

Oxidative stress in Alzheimer’s disease

(2014) Zhichun Chen et al.   Neuroscience Bulletin

Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity

(2010) Jingbo Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis

(2009) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS