Echinacoside's nigrostriatal dopaminergic protection against 6-OHDA-Induced endoplasmic reticulum stress through reducing the accumulation of Seipin

Neuronal seipin knockout facilitates Aβ-induced neuroinflammation and neurotoxicity via reduction of PPARγ in hippocampus of mouse

(2016) Yun Qian et al.   Journal of Neuroinflammation

Neuroprotective Effects of Echinacoside on Regulating the Stress-Active p38MAPK and NF-κB p52 Signals in the Mice Model of Parkinson’s Disease

(2016) Jingsi Zhang et al.   NEUROCHEMICAL RESEARCH

Understanding Dopaminergic Cell Death Pathways in Parkinson Disease

(2016) Patrick P. Michel et al.   NEURON

Echinacoside Protects Against MPP+-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation

(2016) Qing Zhao et al.   Neuroscience Bulletin

Phloridzin-sensitive transport of echinacoside and acteoside and altered intestinal absorption route after application ofCistanche tubulosaextract

(2015) Tadatoshi Tanino et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Larger aggregates of mutant seipin in Celia's Encephalopathy, a new protein misfolding neurodegenerative disease

(2015) Alejandro Ruiz-Riquelme et al.   NEUROBIOLOGY OF DISEASE

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Lack of seipin in neurons results in anxiety- and depression-like behaviors via down regulation of PPARγ

(2014) Libin Zhou et al.   HUMAN MOLECULAR GENETICS

Cerebrospinal fluid lysosomal enzymes and alpha-synuclein in Parkinson's disease

(2014) Lucilla Parnetti et al.   MOVEMENT DISORDERS

CSF α-synuclein and UCH-L1 levels in Parkinson's disease and atypical parkinsonian disorders

(2014) Stefania Mondello et al.   PARKINSONISM & RELATED DISORDERS

Proteomic analysis of human substantia nigra identifies novel candidates involved in Parkinson's disease pathogenesis

(2014) Virginie Licker et al.   PROTEOMICS

Function of seipin: New insights from Bscl2/seipin knockout mouse models

(2013) Lucile Dollet et al.   BIOCHIMIE

Reduced expression of the chaperone-mediated autophagy carrier hsc70 protein in lymphomonocytes of patients with Parkinson's disease

(2013) Gessica Sala et al.   BRAIN RESEARCH

A new seipin-associated neurodegenerative syndrome

(2013) Encarna Guillén-Navarro et al.   JOURNAL OF MEDICAL GENETICS

Motor neuropathy-associated mutation impairs Seipin functions in neurotransmission

(2013) Shunhui Wei et al.   JOURNAL OF NEUROCHEMISTRY

Application of two-phase hollow fiber liquid phase microextraction coupled with high-performance liquid chromatography for the study of the echinacoside pharmacokinetics in Parkinson's disease rat plasma

(2013) Jun Zhou et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Motor neuron degeneration in a mouse model of seipinopathy

(2013) J Guo et al.   Cell Death & Disease

May Serum Levels of Advanced Oxidized Protein Products Serve as a Prognostic Marker of Disease Duration in Patients with Idiopathic Parkinson's Disease?

(2012) José-Manuel García-Moreno et al.   ANTIOXIDANTS & REDOX SIGNALING

ER stress inhibits neuronal death by promoting autophagy

(2012) Antoine Fouillet et al.   Autophagy

Seipin regulates excitatory synaptic transmission in cortical neurons

(2012) Shunhui Wei et al.   JOURNAL OF NEUROCHEMISTRY

Endoplasmic Reticulum Stress Is Important for the Manifestations of  -Synucleinopathy In Vivo

(2012) E. Colla et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic reticulum dysfunction in neurological disease

(2012) Benoit D Roussel et al.   LANCET NEUROLOGY

Neuroanatomical Characterisation of the Expression of the Lipodystrophy and Motor-Neuropathy Gene Bscl2 in Adult Mouse Brain

(2012) Alastair S. Garfield et al.   PLoS One

Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease

(2011) Ivana Devic et al.   BRAIN

Epidemiology and etiology of Parkinson’s disease: a review of the evidence

(2011) Karin Wirdefeldt et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress

(2011) Takuya Yagi et al.   HUMAN MOLECULAR GENETICS

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

(2011) Brit Mollenhauer et al.   LANCET NEUROLOGY

Detection of elevated levels of  -synuclein oligomers in CSF from patients with Parkinson disease

(2011) K. A. Bruggink et al.   NEUROLOGY

InterfERing with endoplasmic reticulum stress

(2011) Honorata Kraskiewicz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Seipin Is a Discrete Homooligomer

(2010) Derk Binns et al.   BIOCHEMISTRY

Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease

(2010) Qing Zhao et al.   BRAIN RESEARCH

Association between high-sensitivity C-reactive protein and risk of early idiopathic Parkinson’s disease

(2010) In-Uk Song et al.   NEUROLOGICAL SCIENCES

The endoplasmic reticulum and neurological diseases

(2009) Wei Yang et al.   EXPERIMENTAL NEUROLOGY

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Inhibition of 6-hydroxydopamine-induced endoplasmic reticulum stress by l-carnosine in SH-SY5Y cells

(2009) Yun-Mi Oh et al.   NEUROSCIENCE LETTERS

Seipinopathy: a novel endoplasmic reticulum stress-associated disease

(2008) Daisuke Ito et al.   BRAIN

Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine

(2008) Jezabel Rodriguez-Blanco et al.   JOURNAL OF NEUROCHEMISTRY

Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease

(2008) Chiung-Mei Chen et al.   NEUROBIOLOGY OF DISEASE