Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures
出版年份 2022 全文链接
标题
Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures
作者
关键词
-
出版物
npj Parkinsons Disease
Volume 8, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-03-21
DOI
10.1038/s41531-022-00282-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Novel Associations of BST1 and LAMP3 with Rapid Eye Movement Sleep Behavior Disorder
- (2021) Kheireddin Mufti et al. NEUROLOGY
- Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome
- (2021) Xiaoping Hong et al. Frontiers in Immunology
- Is LRRK2 the missing link between inflammatory bowel disease and Parkinson’s disease?
- (2021) Mary K. Herrick et al. npj Parkinsons Disease
- Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease
- (2021) Samantha M. Carlisle et al. npj Parkinsons Disease
- Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
- (2021) Hannah Scheiblich et al. CELL
- Autophagy in Parkinson's Disease
- (2020) Xu Hou et al. JOURNAL OF MOLECULAR BIOLOGY
- Chronic Infiltration of T Lymphocytes into the Brain in a Non-human Primate Model of Parkinson’s Disease
- (2020) Jincheol Seo et al. NEUROSCIENCE
- α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
- (2020) Cecilia S. Lindestam Arlehamn et al. Nature Communications
- Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition
- (2020) Gonzalo S. Nido et al. Acta Neuropathologica Communications
- Fractalkine (CX3CL1) signaling and neuroinflammation in Parkinson’s disease: Potential clinical and therapeutic implications
- (2020) Efthalia Angelopoulou et al. PHARMACOLOGICAL RESEARCH
- CX3CR1–CD8+ T cells are critical in antitumor efficacy but functionally suppressed in the tumor microenvironment
- (2020) Takayoshi Yamauchi et al. JCI Insight
- A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo
- (2020) Mahalakshmi Somayaji et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration
- (2019) Dmitri Lodygin et al. NATURE
- Brain cholesterol metabolism and Parkinson's disease
- (2019) Xuemei Huang et al. MOVEMENT DISORDERS
- Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles
- (2019) Yuan Tian et al. JOURNAL OF CLINICAL INVESTIGATION
- Aquaporin 4: A key player in Parkinson's disease
- (2019) Omid Reza Tamtaji et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys
- (2019) Susanta Mondal et al. JOURNAL OF IMMUNOLOGY
- Widespread Tau-Specific CD4 T Cell Reactivity in the General Population
- (2019) Cecilia S. Lindestam Arlehamn et al. JOURNAL OF IMMUNOLOGY
- The physiological role of α‐synuclein and its relationship to Parkinson’s Disease
- (2019) David Sulzer et al. JOURNAL OF NEUROCHEMISTRY
- Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice
- (2019) Diana Matheoud et al. NATURE
- Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment
- (2019) Richard A. Maki et al. FREE RADICAL BIOLOGY AND MEDICINE
- RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
- (2019) Heather D.E. Booth et al. NEUROBIOLOGY OF DISEASE
- Oxidative stress and Parkinson’s disease: conflict of oxidant-antioxidant systems
- (2019) Mohsen Hemmati-Dinarvand et al. NEUROSCIENCE LETTERS
- Cholesterol Metabolism in the Brain and Its Association with Parkinson’s Disease
- (2019) Uram Jin et al. Experimental Neurobiology
- Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue Disease
- (2019) Yuan Tian et al. Cell Reports
- Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo
- (2018) Elena Kozina et al. BRAIN
- The Role of LRRK2 in Neurodegeneration of Parkinson Disease
- (2018) Qin Rui et al. Current Neuropharmacology
- Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling
- (2018) Jenny Sandmark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptomic Analysis of CD4+T Cells Reveals Novel Immune Signatures of Latent Tuberculosis
- (2018) Julie G. Burel et al. JOURNAL OF IMMUNOLOGY
- Overexpression of TFEB Drives a Pleiotropic Neurotrophic Effect and Prevents Parkinson’s Disease-Related Neurodegeneration
- (2018) Albert Torra et al. MOLECULAR THERAPY
- Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease
- (2018) Inga Peter et al. JAMA Neurology
- T cells in patients with narcolepsy target self-antigens of hypocretin neurons
- (2018) Daniela Latorre et al. NATURE
- LRRK2 activation in idiopathic Parkinson’s disease
- (2018) Roberto Di Maio et al. Science Translational Medicine
- Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes
- (2018) Charmaine Lang et al. Cell Stem Cell
- Cutting Edge: Transcriptional Profiling Reveals Multifunctional and Cytotoxic Antiviral Responses of Zika Virus–Specific CD8+ T Cells
- (2018) Alba Grifoni et al. JOURNAL OF IMMUNOLOGY
- The in silico human surfaceome
- (2018) Damaris Bausch-Fluck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Triggers, Facilitators, and Aggravators: Redefining Parkinson’s Disease Pathogenesis
- (2018) Michaela E. Johnson et al. TRENDS IN NEUROSCIENCES
- Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease
- (2017) Tim E. Moors et al. Molecular Neurodegeneration
- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis
- (2016) Carmen Gerlach et al. IMMUNITY
- Advances in markers of prodromal Parkinson disease
- (2016) Ronald B. Postuma et al. Nature Reviews Neurology
- Dysregulation of autophagy and mitochondrial function in Parkinson’s disease
- (2016) Bao Wang et al. Translational Neurodegeneration
- Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array
- (2015) V. Vathipadiekal et al. CLINICAL CANCER RESEARCH
- Parkinson’s disease and enhanced inflammatory response
- (2015) Iva Stojkovska et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- A Mass Spectrometric-Derived Cell Surface Protein Atlas
- (2015) Damaris Bausch-Fluck et al. PLoS One
- The role of the LRRK2 gene in Parkinsonism
- (2014) Jie-Qiong Li et al. Molecular Neurodegeneration
- Full-length RNA-seq from single cells using Smart-seq2
- (2014) Simone Picelli et al. Nature Protocols
- Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
- (2014) T. Raj et al. SCIENCE
- TFEB
- (2013) Mickael Decressac et al. Autophagy
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- -Synuclein in Parkinson's Disease
- (2013) L. Stefanis Cold Spring Harbor Perspectives in Medicine
- Role of Oxidative Stress in Parkinson's Disease
- (2013) Onyou Hwang Experimental Neurobiology
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
- (2012) Lisa Fellner et al. GLIA
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
- (2011) Jisun Lee et al. BIOCHEMICAL JOURNAL
- Molecular signatures database (MSigDB) 3.0
- (2011) A. Liberzon et al. BIOINFORMATICS
- Quality control and preprocessing of metagenomic datasets
- (2011) R. Schmieder et al. BIOINFORMATICS
- Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy
- (2011) Vinay Choubey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- LRRK2 and Parkinson Disease
- (2010) Justus C. Dächsel et al. ARCHIVES OF NEUROLOGY
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of parkin in familial and sporadic Parkinson's disease
- (2010) Ted M. Dawson et al. MOVEMENT DISORDERS
- A CD8+ T cell transcription signature predicts prognosis in autoimmune disease
- (2010) Eoin F McKinney et al. NATURE MEDICINE
- Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
- (2010) Shankar J. Chinta et al. NEUROSCIENCE LETTERS
- Novel expression signatures identified by transcriptional analysis of separated leucocyte subsets in systemic lupus erythematosus and vasculitis
- (2009) P. A. Lyons et al. ANNALS OF THE RHEUMATIC DISEASES
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
- (2009) Mordhwaj S. Parihar et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Phosphorylation of Synucleins by Members of the Polo-like Kinase Family
- (2009) Martial K. Mbefo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV -Synucleinopathy
- (2009) C. Y. Chung et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial association of alpha-synuclein causes oxidative stress
- (2008) M. S. Parihar et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
- (2008) Nelson B. Cole et al. EXPERIMENTAL CELL RESEARCH
- Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain
- (2008) Latha Devi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More