Induction of autophagy-dependent ferroptosis to eliminate drug-tolerant human retinoblastoma cells

Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis

(2022) Xin Chen et al.   Autophagy

Tumor heterogeneity in autophagy-dependent ferroptosis

(2021) Jingbo Li et al.   Autophagy

Broadening horizons: the role of ferroptosis in cancer

(2021) Xin Chen et al.   Nature Reviews Clinical Oncology

Ferritinophagy and ferroptosis in the management of metabolic diseases

(2021) Amir Ajoolabady et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect

(2021) Su Min Lim et al.   Cell and Bioscience

Autophagy-Dependent Apoptosis Induced by Apoferritin–Cu(II) Nanoparticles in Multidrug-Resistant Colon Cancer Cells

(2021) Kai Xiong et al.   ACS Applied Materials & Interfaces

LRPPRC regulates metastasis and glycolysis by modulating autophagy and the ROS/HIF1-α pathway in retinoblastoma

(2021) Kun Song et al.   Molecular Therapy-Oncolytics

Lipid Metabolism in Ferroptosis

(2021) Zhi Lin et al.   Advanced Biology

Itaconic acid induces ferroptosis by activating ferritinophagy

(2021) Chunjing Qu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death

(2020) Changfeng Li et al.   Autophagy

Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death

(2020) Yang Liu et al.   CANCER GENE THERAPY

CD24 blunts the sensitivity of retinoblastoma to vincristine by modulating autophagy

(2020) Jie Sun et al.   Molecular Oncology

ACOD1 in immunometabolism and disease

(2020) Runliu Wu et al.   Cellular & Molecular Immunology

Ferroptosis: machinery and regulation

(2020) Xin Chen et al.   Autophagy

Carboplatin Inhibits the Progression of Retinoblastoma Through IncRNA XIST/miR-200a-3p/NRP1 Axis

(2020) Hong Zhao et al.   Drug Design Development and Therapy

Regulation and function of autophagy in pancreatic cancer

(2020) Jingbo Li et al.   Autophagy

Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics

(2020) Lohans Pedrera et al.   CELL DEATH AND DIFFERENTIATION

The Metabolic Underpinnings of Ferroptosis

(2020) Jiashuo Zheng et al.   Cell Metabolism

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

Chaperone-mediated autophagy is involved in the execution of ferroptosis

(2019) Zheming Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The release and activity of HMGB1 in ferroptosis

(2019) Qirong Wen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

The role of necroptosis in cancer biology and therapy

(2019) Yitao Gong et al.   Molecular Cancer

Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity

(2019) Lindsay DeVorkin et al.   Cell Reports

Clockophagy is a novel selective autophagy process favoring ferroptosis

(2019) Minghua Yang et al.   Science Advances

ESCRT-III–dependent membrane repair blocks ferroptosis

(2019) Enyong Dai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients

(2019) Jean M. Mulcahy Levy et al.   CELL DEATH AND DIFFERENTIATION

OUP accepted manuscript

(2018)   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Autophagy-dependent cell death – where, how and why a cell eats itself to death

(2018) Shani Bialik et al.   JOURNAL OF CELL SCIENCE

Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors

(2018) Jonathan M. Weiss et al.   JOURNAL OF CLINICAL INVESTIGATION

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

Lipid storage and lipophagy regulates ferroptosis

(2018) Yuansong Bai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The clinical value of using chloroquine or hydroxychloroquine as autophagy inhibitors in the treatment of cancers

(2018) Ran Xu et al.   MEDICINE

Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma

(2017) Yangchun Xie et al.   GASTROENTEROLOGY

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

An Autophagic Flux Probe that Releases an Internal Control

(2016) Takeshi Kaizuka et al.   MOLECULAR CELL

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

(2016) Valerian E Kagan et al.   Nature Chemical Biology

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis

(2016) Kenichi Shimada et al.   Nature Chemical Biology

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

(2016) Jan Naujoks et al.   PLoS Pathogens

Retinoblastoma

(2015) Helen Dimaras et al.   Nature Reviews Disease Primers

MIR34Aregulates autophagy and apoptosis by targetingHMGB1in the retinoblastoma cell

(2014) Ke Liu et al.   Autophagy

Increased incidence and disparity of diagnosis of retinoblastoma patients in Guatemala

(2014) Michael Dean et al.   CANCER LETTERS

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies

(2014) Martina McDermott et al.   Frontiers in Oncology

A Complex between Atg7 and Caspase-9

(2013) Jie Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

(2013) A. Michelucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy

(2012) Paola Maycotte et al.   Autophagy

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery

(2011) J R Kovacs et al.   CELL DEATH AND DIFFERENTIATION

Autophagic degradation of active caspase-8

(2010) Wen Hou et al.   Autophagy

Endogenous HMGB1 regulates autophagy

(2010) Daolin Tang et al.   JOURNAL OF CELL BIOLOGY

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

(2010) Laura Bonapace et al.   JOURNAL OF CLINICAL INVESTIGATION