Tumor heterogeneity in autophagy-dependent ferroptosis

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

(2020) Enyong Dai et al.   Autophagy

The mRNA Decay Factor CAR-1/LSM14 Regulates Axon Regeneration via Mitochondrial Calcium Dynamics

(2020) Ngang Heok Tang et al.   CURRENT BIOLOGY

Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death

(2020) Changfeng Li et al.   Autophagy

Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death

(2020) Yang Liu et al.   CANCER GENE THERAPY

SIRT3 deficiency is resistant to autophagy‐dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels

(2020) Dandan Han et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Interplay Between Lipid Metabolism and Autophagy

(2020) Yangchun Xie et al.   Frontiers in Cell and Developmental Biology

Ferroptosis: machinery and regulation

(2020) Xin Chen et al.   Autophagy

Iron Metabolism in Ferroptosis

(2020) Xin Chen et al.   Frontiers in Cell and Developmental Biology

Oxidative Damage and Antioxidant Defense in Ferroptosis

(2020) Feimei Kuang et al.   Frontiers in Cell and Developmental Biology

Regulation and function of autophagy in pancreatic cancer

(2020) Jingbo Li et al.   Autophagy

Ferroptosis: molecular mechanisms and health implications

(2020) Daolin Tang et al.   CELL RESEARCH

Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway

(2020) Enyong Dai et al.   Nature Communications

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

Chaperone-mediated autophagy is involved in the execution of ferroptosis

(2019) Zheming Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The release and activity of HMGB1 in ferroptosis

(2019) Qirong Wen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Clockophagy is a novel selective autophagy process favoring ferroptosis

(2019) Minghua Yang et al.   Science Advances

Autophagic degradation of the circadian clock regulator promotes ferroptosis

(2019) Jiao Liu et al.   Autophagy

Role of TLR4/NADPH oxidase 4 pathway in promoting cell death through autophagy and ferroptosis during heart failure

(2019) Xiaoqing Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells

(2019) Zili Zhang et al.   Autophagy

ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

(2019) Eunhee Park et al.   Cell Death & Disease

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Cargo recognition and degradation by selective autophagy

(2018) Damián Gatica et al.   NATURE CELL BIOLOGY

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis

(2018) Wenjun Deng et al.   Cell Reports

BECN1 is a new driver of ferroptosis

(2018) Rui Kang et al.   Autophagy

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

(2018) Zili Zhang et al.   Autophagy

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

(2018) Xinxin Song et al.   CURRENT BIOLOGY

Autophagy-dependent cell death – where, how and why a cell eats itself to death

(2018) Shani Bialik et al.   JOURNAL OF CELL SCIENCE

Lipid storage and lipophagy regulates ferroptosis

(2018) Yuansong Bai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy-dependent cell death

(2018) Donna Denton et al.   CELL DEATH AND DIFFERENTIATION

Tumour heterogeneity and resistance to cancer therapies

(2017) Ibiayi Dagogo-Jack et al.   Nature Reviews Clinical Oncology

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

(2017) Yangchun Xie et al.   Cell Reports

Iron and cancer: recent insights

(2016) David H. Manz et al.   Annals of the New York Academy of Sciences

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis

(2016) Kenichi Shimada et al.   Nature Chemical Biology

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Posttranslational modification of autophagy-related proteins in macroautophagy

(2014) Yangchun Xie et al.   Autophagy

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Critical contribution of oxidative stress to TNFα-induced necroptosis downstream of RIPK1 activation

(2013) Ryodai Shindo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response

(2013) Petra Haberzettl et al.   Redox Biology

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Ferroportin-mediated iron transport: Expression and regulation

(2012) Diane M. Ward et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Hepcidin-Induced Endocytosis of Ferroportin Is Dependent on Ferroportin Ubiquitination

(2012) Bo Qiao et al.   Cell Metabolism

Endogenous HMGB1 regulates autophagy

(2010) Daolin Tang et al.   JOURNAL OF CELL BIOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Short Form Glutathione Peroxidase 4 Is the Essential Isoform Required for Survival and Somatic Mitochondrial Functions

(2009) Hanyu Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress and Oxidative Damage in Carcinogenesis

(2009) James E. Klaunig et al.   TOXICOLOGIC PATHOLOGY