P-Loop Channels: Experimental Structures, and Physics-Based and Neural Networks-Based Models
出版年份 2022 全文链接
标题
P-Loop Channels: Experimental Structures, and Physics-Based and Neural Networks-Based Models
作者
关键词
-
出版物
Membranes
Volume 12, Issue 2, Pages 229
出版商
MDPI AG
发表日期
2022-02-17
DOI
10.3390/membranes12020229
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Can AlphaFold2 predict the impact of missense mutations on structure?
- (2022) Gwen R. Buel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin
- (2021) Daohua Jiang et al. Nature Communications
- Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav1.5 by the Antiarrhythmic Drug Quinidine
- (2021) Zhangqiang Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Possible Mechanism of Ion Selectivity in Eukaryotic Voltage-Gated Sodium Channels
- (2021) Boris S. Zhorov JOURNAL OF PHYSICAL CHEMISTRY B
- Structural pharmacology of voltage-gated sodium channels
- (2021) Sigrid Noreng et al. JOURNAL OF MOLECULAR BIOLOGY
- Mapping the interaction surface of scorpion β-toxins with an insect sodium channel
- (2021) Boris S. Zhorov et al. BIOCHEMICAL JOURNAL
- Open-state structure and pore gating mechanism of the cardiac sodium channel
- (2021) Daohua Jiang et al. CELL
- Highly accurate protein structure prediction with AlphaFold
- (2021) John Jumper et al. NATURE
- Highly accurate protein structure prediction for the human proteome
- (2021) Kathryn Tunyasuvunakool et al. NATURE
- Advances in TRP channel drug discovery: from target validation to clinical studies
- (2021) Ari-Pekka Koivisto et al. NATURE REVIEWS DRUG DISCOVERY
- Accurate prediction of protein structures and interactions using a three-track neural network
- (2021) Minkyung Baek et al. SCIENCE
- AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
- (2021) Mihaly Varadi et al. NUCLEIC ACIDS RESEARCH
- Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels
- (2021) Kasper B. Hansen et al. PHARMACOLOGICAL REVIEWS
- Intersegment Contacts of Potentially Damaging Variants of Cardiac Sodium Channel
- (2021) Vyacheslav S. Korkosh et al. Frontiers in Pharmacology
- Possible Interactions of Extracellular Loop IVP2-S6 With Voltage-Sensing Domain III in Cardiac Sodium Channel
- (2021) Anastasia K. Zaytseva et al. Frontiers in Pharmacology
- Structure and function of the calcium‐selective TRP channel TRPV6
- (2020) Maria V. Yelshanskaya et al. JOURNAL OF PHYSIOLOGY-LONDON
- Ball-and-chain inactivation in a calcium-gated potassium channel
- (2020) Chen Fan et al. NATURE
- The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism
- (2020) Hiroto Shimada et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Gating of human TRPV3 in a lipid bilayer
- (2020) Zengqin Deng et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The pore domain in glutamate-gated ion channels: Structure, drug binding and similarity with potassium channels
- (2020) Denis B. Tikhonov et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Structural Basis of the Modulation of the Voltage‐Gated Calcium Ion Channel Ca v 1.1 by Dihydropyridine Compounds**
- (2020) Shuai Gao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Atomic Mechanisms of Timothy Syndrome-Associated Mutations in Calcium Channel Cav1.2
- (2019) Vyacheslav S. Korkosh et al. Frontiers in Physiology
- Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA
- (2019) Xiaojing Pan et al. SCIENCE
- Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins
- (2019) Huaizong Shen et al. SCIENCE
- Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel
- (2019) Phuong T. Nguyen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Selectivity Filter Gate Controls Voltage-Gated Calcium Channel Calcium-Dependent Inactivation
- (2019) Fayal Abderemane-Ali et al. NEURON
- Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin
- (2019) Hui Xu et al. CELL
- Regulation of BK Channels by Beta and Gamma Subunits
- (2019) Vivian Gonzalez-Perez et al. Annual Review of Physiology
- Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel
- (2019) Goragot Wisedchaisri et al. CELL
- Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+ Channel
- (2019) Yanyu Zhao et al. CELL
- Emerging roles for multifunctional ion channel auxiliary subunits in cancer
- (2019) Alexander S. Haworth et al. CELL CALCIUM
- Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels
- (2019) William A. Catterall et al. Annual Review of Pharmacology and Toxicology
- The role of π-helices in TRP channel gating
- (2019) Lejla Zubcevic et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Cryo-EM structures of apo and antagonist-bound human Cav3.1
- (2019) Yanyu Zhao et al. NATURE
- Structural basis of temperature sensation by the TRP channel TRPV3
- (2019) Appu K. Singh et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of the Cardiac Sodium Channel
- (2019) Daohua Jiang et al. CELL
- Structural Basis of Human KCNQ1 Modulation and Gating
- (2019) Ji Sun et al. CELL
- A structural overview of the ion channels of the TRPM family
- (2019) Yihe Huang et al. CELL CALCIUM
- Mutational analysis of state-dependent contacts in the pore module of eukaryotic sodium channels
- (2018) Yuzhe Du et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Insight into tetrodotoxin blockade and resistance mechanisms of Nav 1.2 sodium channel by theoretical approaches
- (2018) Lei Xu et al. Chemical Biology & Drug Design
- Searching for New Leads To Treat Epilepsy: Target-Based Virtual Screening for the Discovery of Anticonvulsant Agents
- (2018) Pablo H. Palestro et al. Journal of Chemical Information and Modeling
- Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel
- (2018) Ji She et al. NATURE
- Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors
- (2018) Michael C. Regan et al. NEURON
- Protonation state of inhibitors determines interaction sites within voltage-gated sodium channels
- (2018) Amanda Buyan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and gating mechanism of the transient receptor potential channel TRPV3
- (2018) Appu K. Singh et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors
- (2018) Edward C. Twomey et al. NEURON
- Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1
- (2018) Xiaojing Pan et al. SCIENCE
- Structural basis for the modulation of voltage-gated sodium channels by animal toxins
- (2018) Huaizong Shen et al. SCIENCE
- Selective ion permeation involves complexation with carboxylates and lysine in a model human sodium channel
- (2018) Emelie Flood et al. PLoS Computational Biology
- Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6
- (2018) Appu K. Singh et al. Science Advances
- How CaV1.2-bound verapamil blocks Ca2+ influx into cardiomyocyte: Atomic level views
- (2018) Wei Li et al. PHARMACOLOGICAL RESEARCH
- Structures and gating mechanism of human TRPM2
- (2018) Longfei Wang et al. SCIENCE
- Conformational ensemble of the human TRPV3 ion channel
- (2018) Lejla Zubcevic et al. Nature Communications
- Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants
- (2017) Denis B. Tikhonov et al. JOURNAL OF GENERAL PHYSIOLOGY
- Channel opening and gating mechanism in AMPA-subtype glutamate receptors
- (2017) Edward C. Twomey et al. NATURE
- Opening of the human epithelial calcium channel TRPV6
- (2017) Luke L. McGoldrick et al. NATURE
- Structures of closed and open states of a voltage-gated sodium channel
- (2017) Michael J. Lenaeus et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery and Development of Calcium Channel Blockers
- (2017) Théophile Godfraind Frontiers in Pharmacology
- Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology
- (2016) Annette C. Dolphin JOURNAL OF PHYSIOLOGY-LONDON
- Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
- (2016) Jianping Wu et al. NATURE
- Crystal structure of the epithelial calcium channel TRPV6
- (2016) Kei Saotome et al. NATURE
- Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel
- (2016) Xiao Tao et al. NATURE
- Cryo-electron microscopy structure of the TRPV2 ion channel
- (2016) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Voltage-Gated Potassium Channels: A Structural Examination of Selectivity and Gating
- (2016) Dorothy M. Kim et al. Cold Spring Harbor Perspectives in Biology
- Cryo-electron microscopy structure of the TRPV2 ion channel
- (2016) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Forcing open TRP channels: Mechanical gating as a unifying activation mechanism
- (2015) Chao Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Analysis of inter-residue contacts reveals folding stabilizers in P-loops of potassium, sodium, and TRPV channels
- (2015) V. S. Korkosh et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- The hitchhiker’s guide to the voltage-gated sodium channel galaxy
- (2015) Christopher A. Ahern et al. JOURNAL OF GENERAL PHYSIOLOGY
- Structure of the TRPA1 ion channel suggests regulatory mechanisms
- (2015) Candice E. Paulsen et al. NATURE
- Sodium Channels, Inherited Epilepsy, and Antiepileptic Drugs
- (2014) William A. Catterall Annual Review of Pharmacology and Toxicology
- Structural model of the open–closed–inactivated cycle of prokaryotic voltage-gated sodium channels
- (2014) Claire Bagnéris et al. JOURNAL OF GENERAL PHYSIOLOGY
- Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4
- (2014) Viacheslav S. Korkosh et al. JOURNAL OF GENERAL PHYSIOLOGY
- State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels
- (2014) Denis B. Tikhonov et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Molecular Dynamics Study of Binding of µ-Conotoxin GIIIA to the Voltage-Gated Sodium Channel Nav1.4
- (2014) Somayeh Mahdavi et al. PLoS One
- Locating the Route of Entry and Binding Sites of Benzocaine and Phenytoin in a Bacterial Voltage Gated Sodium Channel
- (2014) Lewis J. Martin et al. PLoS Computational Biology
- Ligand- and Structure-Based Virtual Screening for Clathrodin-Derived Human Voltage-Gated Sodium Channel Modulators
- (2013) Tihomir Tomašić et al. Journal of Chemical Information and Modeling
- TRPV1 structures in distinct conformations reveal activation mechanisms
- (2013) Erhu Cao et al. NATURE
- X-ray structure of the mammalian GIRK2–βγ G-protein complex
- (2013) Matthew R. Whorton et al. NATURE
- Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel
- (2013) M. B. Ulmschneider et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Catalysis of Na+ permeation in the bacterial sodium channel NaVAb
- (2013) N. Chakrabarti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Binding Modes of μ-Conotoxin to the Bacterial Sodium Channel (NaVAb)
- (2012) Rong Chen et al. BIOPHYSICAL JOURNAL
- Voltage-gated sodium channels at 60: structure, function and pathophysiology
- (2012) William A. Catterall JOURNAL OF PHYSIOLOGY-LONDON
- Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
- (2012) Xu Zhang et al. NATURE
- Mechanism of Voltage Gating in Potassium Channels
- (2012) M. O. Jensen et al. SCIENCE
- Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing
- (2012) Emily C. McCusker et al. Nature Communications
- Distinct gating mechanisms revealed by the structures of a multi-ligand gated K+ channel
- (2012) Chunguang Kong et al. eLife
- Mechanism of Ion Permeation and Selectivity in a Voltage Gated Sodium Channel
- (2011) Ben Corry et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- The crystal structure of a voltage-gated sodium channel
- (2011) Jian Payandeh et al. NATURE
- Voltage-Gated Calcium Channels
- (2011) W. A. Catterall Cold Spring Harbor Perspectives in Biology
- Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels
- (2011) Marijke Stevens et al. Frontiers in Pharmacology
- The Tetrodotoxin Binding Site Is within the Outer Vestibule of the Sodium Channel
- (2010) Harry A. Fozzard et al. Marine Drugs
- Structural basis for the coupling between activation and inactivation gates in K+ channels
- (2010) Luis G. Cuello et al. NATURE
- Glutamate Receptor Ion Channels: Structure, Regulation, and Function
- (2010) S. F. Traynelis et al. PHARMACOLOGICAL REVIEWS
- Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels
- (2010) Péter Enyedi et al. PHYSIOLOGICAL REVIEWS
- Structural Model for Dihydropyridine Binding to L-type Calcium Channels
- (2009) Denis B. Tikhonov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Model for Phenylalkylamine Binding to L-type Calcium Channels
- (2009) Ricky C. K. Cheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Gating in CNGA1 channels
- (2009) Monica Mazzolini et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- K+Channel Modulators for the Treatment of Neurological Disorders and Autoimmune Diseases
- (2008) Heike Wulff et al. CHEMICAL REVIEWS
- Molecular Modeling of Benzothiazepine Binding in the L-type Calcium Channel
- (2008) Denis B. Tikhonov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Access and Binding of Local Anesthetics in the Closed Sodium Channel
- (2008) I. Bruhova et al. MOLECULAR PHARMACOLOGY
- Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel
- (2008) G. M. Clayton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now