Rational Design of Pepsin for Enhanced Thermostability via Exploiting the Guide of Structural Weakness on Stability

Soluble Methane Monooxygenase Component Interactions Monitored by 19F NMR

(2021) Jason C. Jones et al.   BIOCHEMISTRY

Heterogeneity in E. coli RecBCD Helicase-DNA Binding and Base Pair Melting

(2021) Linxuan Hao et al.   JOURNAL OF MOLECULAR BIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Accurate prediction of protein structures and interactions using a three-track neural network

(2021) Minkyung Baek et al.   SCIENCE

An Energy Optimization Strategy Based on the Perfect Conformation of Prolyl Endopeptidase for Improving Catalytic Efficiency

(2020) Xiaolin Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structure of the Hydrophobic Core Determines the 3D Protein Structure—Verification by Single Mutation Proteins

(2020) Mateusz Banach et al.   Biomolecules

DeepDDG: Predicting the Stability Change of Protein Point Mutations Using Neural Networks

(2019) Huali Cao et al.   Journal of Chemical Information and Modeling

High-level expression and characterization of a novel aspartic protease from Talaromyces leycettanus JCM12802 and its potential application in juice clarification

(2019) Yujie Guo et al.   FOOD CHEMISTRY

Improving the thermostability and catalytic efficiency of glucose oxidase from Aspergillus niger by molecular evolution

(2019) Tao Tu et al.   FOOD CHEMISTRY

Enhancement of the thermostability of Aspergillus niger α‐ l ‐rhamnosidase based on PoPMuSiC algorithm

(2019) Hui Liao et al.   JOURNAL OF FOOD BIOCHEMISTRY

Thermostability improvement of the glucose oxidase from Aspergillus niger for efficient gluconic acid production via computational design

(2019) Qingxuan Mu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Improvement of BsAPA Aspartic Protease Thermostability via Autocatalysis-Resistant Mutation

(2019) Yujie Guo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Recent advances in the improvement of enzyme thermostability by structure modification

(2019) Zhe Xu et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Lys–Arg mutation improved the thermostability of Bacillus cereus neutral protease through increased residue interactions

(2019) Tolbert Osire et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Quantification of biases in predictions of protein stability changes upon mutations

(2018) Fabrizio Pucci et al.   BIOINFORMATICS

Structure-based design of agarase AgWH50C from Agarivorans gilvus WH0801 to enhance thermostability

(2018) Pujuan Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Improving Thermostability and Catalytic Behavior of l-Rhamnose Isomerase from Caldicellulosiruptor obsidiansis OB47 toward d-Allulose by Site-Directed Mutagenesis

(2018) Ziwei Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Directed Evolution of Recombinant C-Terminal Truncated Staphylococcus epidermidis Lipase AT2 for the Enhancement of Thermostability

(2017) Jiivittha Veno et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FireProt: web server for automated design of thermostable proteins

(2017) Milos Musil et al.   NUCLEIC ACIDS RESEARCH

Two strategies to engineer flexible loops for improved enzyme thermostability

(2017) Haoran Yu et al.   Scientific Reports

Single-site substitutions improve cold activity and increase thermostability of the dehairing alkaline protease (DHAP)

(2016) Hong-Yan Zhao et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Predicting protein thermal stability changes upon point mutations using statistical potentials: Introducing HoTMuSiC

(2016) Fabrizio Pucci et al.   Scientific Reports

Improving the Thermostability and Activity of a Thermophilic Subtilase by Incorporating Structural Elements of Its Psychrophilic Counterpart

(2015) Bi-Lin Xu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The role of proline substitutions within flexible regions on thermostability of luciferase

(2015) Haoran Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Enhancement of the thermostability of Streptomyces kathirae SC-1 tyrosinase by rational design and empirical mutation

(2015) Jing Guo et al.   ENZYME AND MICROBIAL TECHNOLOGY

Enhanced Enzyme Kinetic Stability by Increasing Rigidity within the Active Site

(2014) Yuan Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering proteins for thermostability through rigidifying flexible sites

(2013) Haoran Yu et al.   BIOTECHNOLOGY ADVANCES

Structure- and sequence-analysis inspired engineering of proteins for enhanced thermostability

(2013) Hein J Wijma et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Comparative molecular dynamics simulation studies for determining factors contributing to the thermostability of chemotaxis protein “CheY”

(2013) Manish Paul et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Improved activity and thermostability of Bacillus pumilus lipase by directed evolution

(2013) Nagihan Akbulut et al.   JOURNAL OF BIOTECHNOLOGY

Engineering the loops in a lipase for stability in DMSO

(2013) Poornima Yedavalli et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A method to rationally increase protein stability based on the charge-charge interaction, with application to lipase LipK107

(2013) Lujia Zhang et al.   PROTEIN SCIENCE

Antimicrobial efficacy of pepsin-digested bovine lactoferrin on spoilage bacteria contaminating traditional Mozzarella cheese

(2012) Laura Quintieri et al.   FOOD MICROBIOLOGY

PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality

(2011) Yves Dehouck et al.   BMC BIOINFORMATICS

A role for flexible loops in enzyme catalysis

(2010) M Merced Malabanan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS