标题
Two strategies to engineer flexible loops for improved enzyme thermostability
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-02-01
DOI
10.1038/srep41212
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lower Protein Stability Does Not Necessarily Increase Local Dynamics
- (2016) Levi J. McClelland et al. BIOCHEMISTRY
- Impact of cofactor-binding loop mutations on thermotolerance and activity of E. coli transketolase
- (2016) P. Morris et al. ENZYME AND MICROBIAL TECHNOLOGY
- Transketolase catalysed upgrading of l-arabinose: the one-step stereoselective synthesis of l-gluco-heptulose
- (2016) Fabiana Subrizi et al. GREEN CHEMISTRY
- Mapping the Aggregation Kinetics of a Therapeutic Antibody Fragment
- (2016) Nesrine Chakroun et al. MOLECULAR PHARMACEUTICS
- Versatile Peptide C-Terminal Functionalization via a Computationally Engineered Peptide Amidase
- (2016) Bian Wu et al. ACS Catalysis
- Engineering a Thermostable Transketolase for Unnatural Conversion of (2S )-Hydroxyaldehydes
- (2015) Juliane Abdoul Zabar et al. ADVANCED SYNTHESIS & CATALYSIS
- The role of proline substitutions within flexible regions on thermostability of luciferase
- (2015) Haoran Yu et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- A thermostable transketolase evolved for aliphatic aldehyde acceptors
- (2015) Dong Yi et al. CHEMICAL COMMUNICATIONS
- Second generation engineering of transketolase for polar aromatic aldehyde substrates
- (2015) Panwajee Payongsri et al. ENZYME AND MICROBIAL TECHNOLOGY
- Understanding the Thermostability and Activity of Bacillus subtilis Lipase Mutants: Insights from Molecular Dynamics Simulations
- (2015) Bipin Singh et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Computationally designed libraries for rapid enzyme stabilization
- (2014) H. J. Wijma et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Engineering of Flexible Loops in Enzymes
- (2014) Bettina M. Nestl et al. ACS Catalysis
- Stability and rigidity/flexibility—Two sides of the same coin?
- (2013) Tatyana B. Mamonova et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Engineering proteins for thermostability through rigidifying flexible sites
- (2013) Haoran Yu et al. BIOTECHNOLOGY ADVANCES
- Deletion of a dynamic surface loop improves stability and changes kinetic behavior of phosphatidylinositol-synthesizingStreptomycesphospholipase D
- (2013) Jasmina Damnjanović et al. BIOTECHNOLOGY AND BIOENGINEERING
- Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling
- (2013) Corentin Herbert et al. CANCER CELL
- Stabilizing biocatalysts
- (2013) Andreas S. Bommarius et al. CHEMICAL SOCIETY REVIEWS
- Comparative molecular dynamics simulation studies for determining factors contributing to the thermostability of chemotaxis protein “CheY”
- (2013) Manish Paul et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- A multi-factors rational design strategy for enhancing the thermostability of Escherichia coli AppA phytase
- (2013) Baojin Fei et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Engineering the loops in a lipase for stability in DMSO
- (2013) Poornima Yedavalli et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Improving the thermostability of lipase Lip2 from Yarrowia lipolytica
- (2012) Sai Wen et al. JOURNAL OF BIOTECHNOLOGY
- Rational substrate and enzyme engineering of transketolase for aromatics
- (2012) Panwajee Payongsri et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Assessing Predictors of Changes in Protein Stability upon Mutation Using Self-Consistency
- (2012) Grant Thiltgen et al. PLoS One
- Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies
- (2012) Nicholas Furnham et al. PLoS Computational Biology
- Development of thermostable Candida antarctica lipase B through novel in silico design of disulfide bridge
- (2011) Quang Anh Tuan Le et al. BIOTECHNOLOGY AND BIOENGINEERING
- Strategy and success for the directed evolution of enzymes
- (2011) Paul A Dalby CURRENT OPINION IN STRUCTURAL BIOLOGY
- Structural stability of E. coli transketolase to temperature and pH denaturation
- (2011) Raha R.F. Jahromi et al. JOURNAL OF BIOTECHNOLOGY
- α,α′-Dihydroxyketone formation using aromatic and heteroaromatic aldehydes with evolved transketolase enzymes
- (2010) James L. Galman et al. CHEMICAL COMMUNICATIONS
- Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst
- (2010) Andreas S Bommarius et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- A role for flexible loops in enzyme catalysis
- (2010) M Merced Malabanan et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Development of thermostable lipase B from Candida antarctica (CalB) through in silico design employing B-factor and RosettaDesign
- (2010) Hyun Sook Kim et al. ENZYME AND MICROBIAL TECHNOLOGY
- Non-α-hydroxylated aldehydes with evolved transketolase enzymes
- (2010) Armando Cázares et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Thermostabilization of an esterase by alignment-guided focussed directed evolution
- (2010) Helge Jochens et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Role of conformational sampling in computing mutation-induced changes in protein structure and stability
- (2010) Elizabeth H. Kellogg et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Enhancing and Reversing the Stereoselectivity ofEscherichia coliTransketolaseviaSingle-Point Mutations
- (2008) Mark E. B. Smith et al. ADVANCED SYNTHESIS & CATALYSIS
- Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde
- (2008) E HIBBERT et al. JOURNAL OF BIOTECHNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now