NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions
出版年份 2021 全文链接
标题
NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions
作者
关键词
-
出版物
Cells
Volume 10, Issue 11, Pages 2828
出版商
MDPI AG
发表日期
2021-10-22
DOI
10.3390/cells10112828
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies
- (2021) Suowen Xu et al. PHARMACOLOGICAL REVIEWS
- Role of the Nucleotide-Binding Domain-Like Receptor Protein 3 Inflammasome in the Endothelial Dysfunction of Early Sepsis
- (2020) Minghao Luo et al. INFLAMMATION
- NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture
- (2020) Denise C. Cornelius et al. PLoS One
- The NLRP3 Inflammasome Role in the Pathogenesis of Pregnancy Induced Hypertension and Preeclampsia
- (2020) Maciej W. Socha et al. Cells
- Preeclampsia—Pathophysiology and Clinical Presentations
- (2020) Christopher W. Ives et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Preeclampsia
- (2019) Sarosh Rana et al. CIRCULATION RESEARCH
- A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury
- (2019) Ram Kuwar et al. Journal of Neuroinflammation
- MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
- (2019) Rebecca C. Coll et al. Nature Chemical Biology
- The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
- (2019) Nathan Kelley et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pre-eclampsia: pathophysiology and clinical implications
- (2019) Graham J Burton et al. BMJ-British Medical Journal
- Development of the human placenta
- (2019) Margherita Y. Turco et al. DEVELOPMENT
- Inflammasomes: Their Role in Normal and Complicated Pregnancies
- (2019) Nardhy Gomez-Lopez et al. JOURNAL OF IMMUNOLOGY
- Pharmacological Inhibitors of the NLRP3 Inflammasome
- (2019) Ayesha Zahid et al. Frontiers in Immunology
- Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors
- (2019) Shi-Bin Cheng et al. Cell Death & Disease
- NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus
- (2019) Nathanne Santos Ferreira et al. Cells
- NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis
- (2018) Alena Grebe et al. CIRCULATION RESEARCH
- The NLRP3 rs10754558 polymorphism is a risk factor for preeclampsia in a Chinese Han population
- (2018) Longqiang Xu et al. Journal of Maternal-Fetal & Neonatal Medicine
- Structural Insights of Benzenesulfonamide Analogues as NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization
- (2018) Jacob Fulp et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting the NLRP3 inflammasome in inflammatory diseases
- (2018) Matthew S. J. Mangan et al. NATURE REVIEWS DRUG DISCOVERY
- OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
- (2018) Carlo Marchetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity
- (2018) Hongbin He et al. Nature Communications
- Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders
- (2017) Hua Jiang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Glibenclamide inhibits NLRP3 inflammasome-mediated IL-1β secretion in human trophoblasts
- (2017) Kazuhiro Tamura et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Advanced glycation end products regulate interleukin-1β production in human placenta
- (2017) Kotomi SENO et al. JOURNAL OF REPRODUCTION AND DEVELOPMENT
- Increased expression of NLRP3 inflammasome in placentas from pregnant women with severe preeclampsia
- (2017) Ingrid C.Weel et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- The NLRP3 inflammasome in acute myocardial infarction
- (2017) Stefano Toldo et al. Nature Reviews Cardiology
- Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
- (2017) Jianjin Shi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Oridonin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-induced RAW264.7 cells and acute lung injury
- (2017) Gan Zhao et al. Oncotarget
- Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
- (2016) Michael A. Gimbrone et al. CIRCULATION RESEARCH
- Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation
- (2016) Michael J. Primiano et al. JOURNAL OF IMMUNOLOGY
- Uric Acid Crystals Induce Placental Inflammation and Alter Trophoblast Function via an IL-1–Dependent Pathway: Implications for Fetal Growth Restriction
- (2016) Marie-Eve Brien et al. JOURNAL OF IMMUNOLOGY
- Contribution of redox-dependent activation of endothelial Nlrp3 inflammasomes to hyperglycemia-induced endothelial dysfunction
- (2016) Yang Chen et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Pre-eclampsia
- (2016) Ben W J Mol et al. LANCET
- SIRT1 inhibits inflammatory response partly through regulation of NLRP3 inflammasome in vascular endothelial cells
- (2016) Yanxiang Li et al. MOLECULAR IMMUNOLOGY
- Mechanism and Regulation of NLRP3 Inflammasome Activation
- (2016) Yuan He et al. TRENDS IN BIOCHEMICAL SCIENCES
- Caveolae: A Role in Endothelial Inflammation and Mechanotransduction?
- (2016) Waled A. Shihata et al. Frontiers in Physiology
- Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?
- (2015) Justine M. Abais et al. ANTIOXIDANTS & REDOX SIGNALING
- Coronary Endothelial Dysfunction Induced by Nucleotide Oligomerization Domain-Like Receptor Protein with Pyrin Domain Containing 3 Inflammasome Activation During Hypercholesterolemia: Beyond Inflammation
- (2015) Yang Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia
- (2015) Dania A. Shah et al. BIOCHEMICAL PHARMACOLOGY
- Serum levels of endocan correlate with the presence and severity of pre-eclampsia
- (2015) Muzaffer Cakmak et al. CLINICAL AND EXPERIMENTAL HYPERTENSION
- Severe preeclampsia: Association of genes polymorphisms and maternal cytokines production in Brazilian population
- (2015) Melina B. Pinheiro et al. CYTOKINE
- NLRP3 Deficiency Improves Angiotensin II-Induced Hypertension But Not Fetal Growth Restriction During Pregnancy
- (2015) Koumei Shirasuna et al. ENDOCRINOLOGY
- Pregnancy-Induced hypertension
- (2015) Evangelia Kintiraki et al. Hormones-International Journal of Endocrinology and Metabolism
- Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse
- (2015) Carlo Marchetti et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Instigation of endothelial Nlrp3 inflammasome by adipokine visfatin promotes inter-endothelial junction disruption: role of HMGB1
- (2015) Yang Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
- (2015) Yun-Hee Youm et al. NATURE MEDICINE
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Tranilast: A review of its therapeutic applications
- (2015) Sara Darakhshan et al. PHARMACOLOGICAL RESEARCH
- Molecular mechanisms of maternal vascular dysfunction in preeclampsia
- (2015) Styliani Goulopoulou et al. TRENDS IN MOLECULAR MEDICINE
- Reactive oxygen species and mitochondria: A nexus of cellular homeostasis
- (2015) Joe Dan Dunn et al. Redox Biology
- Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia
- (2015) Mariana Leticia Matias et al. PLoS One
- NLRP1L155H Polymorphism is a Risk Factor for Preeclampsia Development
- (2014) Alessandra Pontillo et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Mechanism of NLRP3 inflammasome activation
- (2014) Fayyaz S. Sutterwala et al. Annals of the New York Academy of Sciences
- Endothelial dysfunction
- (2014) Zhen Chen et al. CURRENT OPINION IN LIPIDOLOGY
- How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1
- (2014) Peter A. Keyel CYTOKINE
- Intracellular Glutathione Depletion by Oridonin Leads to Apoptosis in Hepatic Stellate Cells
- (2014) Liang-Mou Kuo et al. MOLECULES
- Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC
- (2014) Koumei Shirasuna et al. Nanotoxicology
- The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP
- (2014) A.L. Tranquilli et al. Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health
- A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome
- (2013) Wen Liu et al. BIOCHEMICAL PHARMACOLOGY
- A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia–Reperfusion in the Mouse
- (2013) Carlo Marchetti et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Vascular Dysfunction in Preeclampsia
- (2013) Lesley J. Brennan et al. MICROCIRCULATION
- Identification of interleukin-1 beta, but no other inflammatory proteins, as an early onset pre-eclampsia biomarker in first trimester serum by bead-based multiplexed immunoassays
- (2013) Jacqueline E. Siljee et al. PRENATAL DIAGNOSIS
- Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer
- (2013) A D'Anneo et al. Cell Death & Disease
- The elevation in circulating anti-angiogenic factors is independent of markers of neutrophil activation in preeclampsia
- (2012) Wenda Ramma et al. ANGIOGENESIS
- Uric Acid Induces Trophoblast IL-1β Production Via the Inflammasome: Implications for the Pathogenesis of Preeclampsia
- (2011) Melissa J. Mulla et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Monocytic microparticles activate endothelial cells in an IL-1 -dependent manner
- (2011) J.-G. Wang et al. BLOOD
- Mechanisms and Potential Therapies for Preeclampsia
- (2011) Eric M. George et al. CURRENT HYPERTENSION REPORTS
- Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: the importance of IL-1beta and high-mobility group box 1
- (2011) M. Maroso et al. JOURNAL OF INTERNAL MEDICINE
- Measurement of spiral artery jets: general principles and differences observed in small-for-gestational-age pregnancies
- (2011) S. L. Collins et al. ULTRASOUND IN OBSTETRICS & GYNECOLOGY
- Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia
- (2010) F Xie et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome
- (2010) Christine Juliana et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
- (2009) Mohamed Lamkanfi et al. JOURNAL OF CELL BIOLOGY
- Randomized controlled trial design in rheumatoid arthritis: the past decade
- (2009) Vibeke Strand et al. ARTHRITIS RESEARCH & THERAPY
- A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate
- (2008) Roberto Romero et al. Journal of Maternal-Fetal & Neonatal Medicine
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