Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation
出版年份 2016 全文链接
标题
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation
作者
关键词
-
出版物
JOURNAL OF IMMUNOLOGY
Volume 197, Issue 6, Pages 2421-2433
出版商
The American Association of Immunologists
发表日期
2016-08-13
DOI
10.4049/jimmunol.1600035
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cytokines in psoriasis
- (2015) Jaymie Baliwag et al. CYTOKINE
- IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome
- (2015) Hanitriniaina Rabeony et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Inflammasomes: mechanism of action, role in disease and therapeutics
- (2015) Haitao Guo et al. NATURE MEDICINE
- How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1
- (2014) Peter A. Keyel CYTOKINE
- The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
- (2014) Alberto Baroja-Mazo et al. NATURE IMMUNOLOGY
- The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
- (2014) Bernardo S Franklin et al. NATURE IMMUNOLOGY
- Is the inflammasome a potential therapeutic target in renal disease?
- (2014) Clare M Turner et al. BMC Nephrology
- New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease
- (2013) Dominic De Nardo et al. AMERICAN JOURNAL OF PATHOLOGY
- Analysis of Pfizer Compounds in EPA’s ToxCast Chemicals-Assay Space
- (2013) Falgun Shah et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Profiling 976 ToxCast Chemicals across 331 Enzymatic and Receptor Signaling Assays
- (2013) Nisha S. Sipes et al. CHEMICAL RESEARCH IN TOXICOLOGY
- TLRs to cytokines: Mechanistic insights from the imiquimod mouse model of psoriasis
- (2013) Barry Flutter et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation
- (2013) Yiqing Yan et al. IMMUNITY
- Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
- (2013) Erik C Hett et al. Nature Chemical Biology
- Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
- (2013) Hideki Hara et al. NATURE IMMUNOLOGY
- Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis
- (2013) Georg Lorenz et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Treating inflammation by blocking interleukin-1 in humans
- (2013) Charles A. Dinarello et al. SEMINARS IN IMMUNOLOGY
- Aldara activates TLR7-independent immune defence
- (2013) Anne Walter et al. Nature Communications
- Regulation of interleukin 1α secretion by inflammasomes: Table 1
- (2012) Amir S Yazdi et al. ANNALS OF THE RHEUMATIC DISEASES
- Genetic support for the role of the NLRP3 inflammasome in psoriasis susceptibility
- (2012) Maria Carlström et al. EXPERIMENTAL DERMATOLOGY
- Critical Role for Mast Cells in Interleukin-1β-Driven Skin Inflammation Associated with an Activating Mutation in the Nlrp3 Protein
- (2012) Yuumi Nakamura et al. IMMUNITY
- Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1
- (2012) Olaf Groß et al. IMMUNITY
- Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
- (2012) Monique A.M. Willart et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Analysis of NLRP3 in the Development of Allergic Airway Disease in Mice
- (2012) I. C. Allen et al. JOURNAL OF IMMUNOLOGY
- Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
- (2012) Charles A. Dinarello et al. NATURE REVIEWS DRUG DISCOVERY
- Cryopyrin-Associated Periodic Syndromes
- (2012) Takako Miyamae PEDIATRIC DRUGS
- NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant
- (2011) A.-G. Besnard et al. ALLERGY
- Acidic Mammalian Chitinase Is Not a Critical Target for Allergic Airway Disease
- (2011) Lori J. Fitz et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- An Unexpected Role for Uric Acid as an Inducer of T Helper 2 Cell Immunity to Inhaled Antigens and Inflammatory Mediator of Allergic Asthma
- (2011) Mirjam Kool et al. IMMUNITY
- IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway
- (2011) Kyung-Ah Cho et al. INTERNATIONAL IMMUNOLOGY
- IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression
- (2011) A. Johnston et al. JOURNAL OF IMMUNOLOGY
- Serum Amyloid A Activates the NLRP3 Inflammasome and Promotes Th17 Allergic Asthma in Mice
- (2011) J. L. Ather et al. JOURNAL OF IMMUNOLOGY
- Potent and Selective Inhibitors of GlutathioneS-Transferase Omega 1 That Impair Cancer Drug Resistance
- (2011) Katsunori Tsuboi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
- (2011) Yue Zhao et al. NATURE
- The Inflammasome in Atherosclerosis and Type 2 Diabetes
- (2011) S. L. Masters et al. Science Translational Medicine
- A Potential Role for P2X7R in Allergic Airway Inflammation in Mice and Humans
- (2010) Tobias Müller et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Psoriasis: what we have learned from mouse models
- (2010) Erwin F. Wagner et al. Nature Reviews Rheumatology
- Rilonacept for the treatment of cryopyrin-associated periodic syndromes (CAPS)
- (2009) Hal M Hoffman EXPERT OPINION ON BIOLOGICAL THERAPY
- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
- (2009) Mohamed Lamkanfi et al. JOURNAL OF CELL BIOLOGY
- Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria
- (2009) Yuumi Nakamura et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways
- (2009) S. B. Willingham et al. JOURNAL OF IMMUNOLOGY
- Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
- (2009) S. S. Iyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started