Contribution of redox-dependent activation of endothelial Nlrp3 inflammasomes to hyperglycemia-induced endothelial dysfunction

High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

(2016) Hong Feng et al.   Journal of Diabetes Research

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

(2015) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

Coronary Endothelial Dysfunction Induced by Nucleotide Oligomerization Domain-Like Receptor Protein with Pyrin Domain Containing 3 Inflammasome Activation During Hypercholesterolemia: Beyond Inflammation

(2015) Yang Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of autophagy induces IL-1β release from ARPE-19 cells via ROS mediated NLRP3 inflammasome activation under high glucose stress

(2015) Huanqi Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis

(2015) Yang Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity

(2015) Orla M. Finucane et al.   DIABETES

Regulation of NOD-like receptors and inflammasome activation in cerebral endothelial cells

(2015) Péter Nagyőszi et al.   JOURNAL OF NEUROCHEMISTRY

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

(2015) Khurrum Shahzad et al.   KIDNEY INTERNATIONAL

Vimentin regulates activation of the NLRP3 inflammasome

(2015) Gimena dos Santos et al.   Nature Communications

Endothelial NLRP3 Inflammasome Activation and Enhanced Neointima Formation in Mice by Adipokine Visfatin

(2014) Min Xia et al.   AMERICAN JOURNAL OF PATHOLOGY

Shear Stress–Initiated Signaling and Its Regulation of Endothelial Function

(2014) Jing Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene

(2014) Yang Zhang et al.   CARDIOVASCULAR RESEARCH

How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1

(2014) Peter A. Keyel   CYTOKINE

Enhancement of Autophagy by Simvastatin through Inhibition of Rac1-mTOR Signaling Pathway in Coronary Arterial Myocytes

(2013) Yu-Miao Wei et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Production of Reactive Oxygen Species in the Diabetic Heart

(2013) Yasushi Teshima et al.   CIRCULATION JOURNAL

Hyperglycemia-induced Oxidative Stress and its Role in Diabetes Mellitus Related Cardiovascular Diseases

(2013) Teresa Fiorentino et al.   CURRENT PHARMACEUTICAL DESIGN

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

Inflammasomes: sensors of metabolic stresses for vascular inflammation 

(2013) Xiao-feng Yang   Frontiers in Bioscience-Landmark

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

(2013) Takuma Misawa et al.   NATURE IMMUNOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Novel role of PKR in inflammasome activation and HMGB1 release

(2012) Ben Lu et al.   NATURE

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

(2012) Haitao Wen et al.   NATURE IMMUNOLOGY

HMGB1 Increases Permeability of the Endothelial Cell Monolayer via RAGE and Src Family Tyrosine Kinase Pathways

(2011) Wenchang Huang et al.   INFLAMMATION

High-Glucose Stimulation Increases Reactive Oxygen Species Production Through the Calcium and Mitogen-Activated Protein Kinase-Mediated Activation of Mitochondrial Fission

(2010) Tianzheng Yu et al.   ANTIOXIDANTS & REDOX SIGNALING

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Activation of Protein Kinase C Isoforms and Its Impact on Diabetic Complications

(2010) Pedro Geraldes et al.   CIRCULATION RESEARCH

HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption

(2010) Rachel K. Wolfson et al.   MICROVASCULAR RESEARCH

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

(2009) D. Yao et al.   DIABETES

Molecular and clinical aspects of endothelial dysfunction in diabetes

(2009) Carmela Nacci et al.   Internal and Emergency Medicine

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Endothelial Dysfunction in Diabetes: From Mechanisms to Therapeutic Targets

(2008) Maria Potenza et al.   CURRENT MEDICINAL CHEMISTRY

Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting

(2008) W Todd Cade   PHYSICAL THERAPY

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis

(2007) Yann Wallez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES