Mitochondrial Function and Parkinson’s Disease: From the Perspective of the Electron Transport Chain
出版年份 2021 全文链接
标题
Mitochondrial Function and Parkinson’s Disease: From the Perspective of the Electron Transport Chain
作者
关键词
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出版物
Frontiers in Molecular Neuroscience
Volume 14, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-12-09
DOI
10.3389/fnmol.2021.797833
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmacological advances in mitochondrial therapy
- (2021) Aarti Singh et al. EBioMedicine
- Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes
- (2021) C. Alexander Boecker et al. CURRENT BIOLOGY
- Genome instability and loss of protein homeostasis: converging paths to neurodegeneration?
- (2021) Anna Ainslie et al. Open Biology
- Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease
- (2021) Chun Chen et al. npj Parkinsons Disease
- Molecular mechanisms of cell death in neurological diseases
- (2021) Diane Moujalled et al. CELL DEATH AND DIFFERENTIATION
- UQCRC1 engages cytochrome c for neuronal apoptotic cell death
- (2021) Yu-Chien Hung et al. Cell Reports
- Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein
- (2021) André D. G. Leitão et al. Communications Biology
- Chchd2 regulates mitochondrial morphology by modulating the levels of Opa1
- (2020) Wei Liu et al. CELL DEATH AND DIFFERENTIATION
- The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration
- (2020) Anne-Laure Mahul-Mellier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72
- (2020) Sophie Vieweg et al. BIOCHEMICAL JOURNAL
- Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
- (2020) Yi-Ting Liu et al. HUMAN MOLECULAR GENETICS
- The emerging role of α-synuclein truncation in aggregation and disease
- (2020) Zachary A. Sorrentino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impact of GBA1 variants on long-term clinical progression and mortality in incident Parkinson’s disease
- (2020) Thomas B Stoker et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease
- (2020) Preston Ge et al. Molecular Neurodegeneration
- Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans
- (2020) Jia Nee Foo et al. JAMA Neurology
- The role of genetics in Parkinson’s disease: a large cohort study in Chinese mainland population
- (2020) Yuwen Zhao et al. BRAIN
- Genetic and Phenotypic Basis of Autosomal Dominant Parkinson's Disease in a Large Multi-Center Cohort
- (2020) Suzanne Lesage et al. Frontiers in Neurology
- Ubiquinol-cytochrome c reductase core protein 1 overexpression protects H9c2 cardiac cells against mimic ischemia/reperfusion injury through PI3K/Akt/GSK-3β pathway
- (2020) Tingting Yi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Novel and reported variants in Parkinson's disease genes confer high disease burden among Indians
- (2020) Sumeet Kumar et al. PARKINSONISM & RELATED DISORDERS
- Mitochondrial DNA damage as a potential biomarker of LRRK2 kinase activity in LRRK2 Parkinson’s disease
- (2020) C. P. Gonzalez-Hunt et al. Scientific Reports
- Mitochondrial Mechanisms of LRRK2 G2019S Penetrance
- (2020) Sylvie Delcambre et al. Frontiers in Neurology
- The interplay between GCase, α-synuclein and lipids in human models of Parkinson’s disease
- (2020) Sonia Sanz Muñoz et al. BIOPHYSICAL CHEMISTRY
- Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration
- (2019) Xinhe Wang et al. Acta Neuropathologica Communications
- Parkinson's Disease and the Environment
- (2019) Nicole Ball et al. Frontiers in Neurology
- A clinical and genetic study of early-onset and familial parkinsonism in taiwan: An integrated approach combining gene dosage analysis and next-generation sequencing
- (2019) Chin-Hsien Lin et al. MOVEMENT DISORDERS
- LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10
- (2019) Fieke Wauters et al. Autophagy
- Mitochondrial electron transport chain, ROS generation and uncoupling (Review)
- (2019) Ru‑Zhou Zhao et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Genetic analysis of Mendelian mutations in a large UK population-based Parkinson’s disease study
- (2019) Manuela M.X. Tan et al. BRAIN
- Linking mitochondrial dynamics, cristae remodeling and supercomplex formation: How mitochondrial structure can regulate bioenergetics
- (2019) Nicole Baker et al. MITOCHONDRION
- Parkinson’s disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth
- (2019) Rongmin Chen et al. Cell Death & Disease
- Tryptophan Oxidation in the UQCRC1 Subunit of Mitochondrial Complex III (Ubiquinol-Cytochrome C Reductase) in a Mouse Model of Myodegeneration Causes Large Structural Changes in the Complex: A Molecular Dynamics Simulation Study
- (2019) Sruthi Unni et al. Scientific Reports
- Serine-47 phosphorylation of cytochrome c in the mammalian brain regulates cytochrome c oxidase and caspase-3 activity
- (2019) Hasini A. Kalpage et al. FASEB JOURNAL
- Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases
- (2019) Rachel C. Gomez et al. JOURNAL OF CELL BIOLOGY
- A split-GFP tool reveals differences in the sub-mitochondrial distribution of wt and mutant alpha-synuclein
- (2019) Mattia Vicario et al. Cell Death & Disease
- The LRRK2-RAB axis in regulation of vesicle trafficking and α-synuclein propagation
- (2019) Eun-Jin Bae et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
- (2019) Mike A Nalls et al. LANCET NEUROLOGY
- LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same
- (2019) Daniel C. Berwick et al. Molecular Neurodegeneration
- LRRK2 and mitochondria: Recent advances and current views
- (2018) Alpana Singh et al. BRAIN RESEARCH
- Mitochondrial complex III Rieske Fe-S protein processing and assembly
- (2018) Erika Fernandez-Vizarra et al. CELL CYCLE
- Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain
- (2018) Guang Lin et al. Cell Metabolism
- Nuclear cytochrome c - a mitochondrial visitor regulating damaged chromatin dynamics
- (2018) Irene Díaz-Moreno et al. FEBS LETTERS
- Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain
- (2018) Penelope J. Hallett et al. NEUROBIOLOGY OF AGING
- Oxidative stress is tightly regulated by cytochromecphosphorylation and respirasome factors in mitochondria
- (2018) Alejandra Guerra-Castellano et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
- (2018) Marthe H. R. Ludtmann et al. Nature Communications
- An Essential Role for ECSIT in Mitochondrial Complex I Assembly and Mitophagy in Macrophages
- (2018) Flávia R.G. Carneiro et al. Cell Reports
- The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease
- (2018) David C. Schöndorf et al. Cell Reports
- The Parkinson Pandemic—A Call to Action
- (2018) E. Ray Dorsey et al. JAMA Neurology
- Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging
- (2018) Marioly Müller et al. Frontiers in Neuroscience
- On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease
- (2018) Nicolas Giguère et al. Frontiers in Neurology
- Tissue-specific regulation of cytochrome c by post-translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis
- (2018) Hasini A. Kalpage et al. FASEB JOURNAL
- LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis
- (2018) Tomoya Eguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distribution of oxidized DJ-1 in Parkinson’s disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin
- (2018) Yuichiro Mita et al. Scientific Reports
- PD-linked CHCHD2 mutations impair CHCHD10 and MICOS complex leading to mitochondria dysfunction
- (2018) Wei Zhou et al. HUMAN MOLECULAR GENETICS
- Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- (2018) E. Ray Dorsey et al. LANCET NEUROLOGY
- LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network
- (2017) Zhiyong Liu et al. HUMAN MOLECULAR GENETICS
- Glitazone use associated with reduced risk of Parkinson's disease
- (2017) Brage Brakedal et al. MOVEMENT DISORDERS
- Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c
- (2017) Hongrui Meng et al. Nature Communications
- PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival
- (2017) Yunjong Lee et al. Cell Reports
- The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells
- (2017) Ionica Masgras et al. Frontiers in Oncology
- Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease
- (2016) Chung-Han Hsieh et al. Cell Stem Cell
- Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease
- (2016) Joana Magalhaes et al. HUMAN MOLECULAR GENETICS
- Genome-wide association study of Parkinson’s disease in East Asians
- (2016) Jia Nee Foo et al. HUMAN MOLECULAR GENETICS
- Muscle biopsies from human muscle diseases with myopathic pathology reveal common alterations in mitochondrial function
- (2016) Balaraju Sunitha et al. JOURNAL OF NEUROCHEMISTRY
- Mitochondrial dysfunction associated with glucocerebrosidase deficiency
- (2016) Matthew E. Gegg et al. NEUROBIOLOGY OF DISEASE
- Absence of Lewy pathology associated with PINK1 homozygous mutation
- (2016) Masashi Takanashi et al. NEUROLOGY
- Stage-Specific Changes in the Water, Na+, Cl- and K+ Contents of Organelles during Apoptosis, Demonstrated by a Targeted Cryo Correlative Analytical Approach
- (2016) Frédérique Nolin et al. PLoS One
- Mitochondrial Proteins Containing Coiled-Coil-Helix-Coiled-Coil-Helix (CHCH) Domains in Health and Disease
- (2016) Nazanine Modjtahedi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
- (2016) Martin Steger et al. eLife
- Mitochondrial diseases
- (2016) Gráinne S. Gorman et al. Nature Reviews Disease Primers
- Loss ofPLA2G6leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction
- (2015) Kerri J. Kinghorn et al. BRAIN
- PINK1 and Parkin Control Localized Translation of Respiratory Chain Component mRNAs on Mitochondria Outer Membrane
- (2015) Stephan Gehrke et al. Cell Metabolism
- CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study
- (2015) Manabu Funayama et al. LANCET NEUROLOGY
- Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial
- (2015) LANCET NEUROLOGY
- MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism
- (2015) Siddhesh Aras et al. MITOCHONDRION
- MDS clinical diagnostic criteria for Parkinson's disease
- (2015) Ronald B. Postuma et al. MOVEMENT DISORDERS
- Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochromec
- (2015) Katiuska González-Arzola et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons
- (2015) A K Reeve et al. Cell Death & Disease
- Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
- (2015) Mario de la Mata et al. Scientific Reports
- Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study
- (2015) Ruth Brauer et al. PLOS MEDICINE
- Immunostaining of Oxidized DJ-1 in Human and Mouse Brains
- (2014) Yoshiro Saito et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Detailed analysis of mitochondrial respiratory chain defects caused by loss of PINK1
- (2014) Taku Amo et al. NEUROSCIENCE LETTERS
- An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore
- (2014) K. N. Alavian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
- (2014) V. A. Morais et al. SCIENCE
- The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy
- (2014) Joe H. Pogson et al. PLoS Genetics
- Disease Penetrance of Late-Onset Parkinsonism
- (2014) Joanne Trinh et al. JAMA Neurology
- A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease
- (2014) et al. JAMA Neurology
- Ceramide and the mitochondrial respiratory chain
- (2013) Aviram Kogot-Levin et al. BIOCHIMIE
- Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease
- (2013) Laura D. Osellame et al. Cell Metabolism
- Ablation of Ceramide Synthase 2 Causes Chronic Oxidative Stress Due to Disruption of the Mitochondrial Respiratory Chain
- (2013) Hila Zigdon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytochrome c Is Tyrosine 97 Phosphorylated by Neuroprotective Insulin Treatment
- (2013) Thomas H. Sanderson et al. PLoS One
- The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
- (2013) E. S. Vincow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain
- (2012) Eduardo Balsa et al. Cell Metabolism
- Restricted diffusion of OXPHOS complexes in dynamic mitochondria delays their exchange between cristae and engenders a transitory mosaic distribution
- (2012) Verena Wilkens et al. JOURNAL OF CELL SCIENCE
- Mimicking Phosphorylation at Serine 87 Inhibits the Aggregation of Human -Synuclein and Protects against Its Toxicity in a Rat Model of Parkinson's Disease
- (2012) A. Oueslati et al. JOURNAL OF NEUROSCIENCE
- Systematic Review and UK-Based Study ofPARK2 (parkin), PINK1, PARK7 (DJ-1)andLRRK2in early-onset Parkinson's disease
- (2012) Laura L. Kilarski et al. MOVEMENT DISORDERS
- Living on the edge with too many mouths to feed: Why dopamine neurons die
- (2012) J. Paul Bolam et al. MOVEMENT DISORDERS
- The neuropathology of genetic Parkinson's disease
- (2012) Markos Poulopoulos et al. MOVEMENT DISORDERS
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- DJ-1 Null Dopaminergic Neuronal Cells Exhibit Defects in Mitochondrial Function and Structure: Involvement of Mitochondrial Complex I Assembly
- (2012) Jun Young Heo et al. PLoS One
- Identification of C6-ceramide-interacting proteins in D6P2T Schwannoma cells
- (2012) Venkatesh Kota et al. PROTEOMICS
- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
- (2011) Joo-Ho Shin et al. CELL
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
- (2011) Joseph R. Mazzulli et al. CELL
- Mitochondrial Electron Transport Chain Complex III Is Required for Antimycin A to Inhibit Autophagy
- (2011) Xiuquan Ma et al. CHEMISTRY & BIOLOGY
- Mitochondrial ATP synthase: architecture, function and pathology
- (2011) An I. Jonckheere et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Neuroaxonal Dystrophy in Calcium-Independent Phospholipase A2 Deficiency Results from Insufficient Remodeling and Degeneration of Mitochondrial and Presynaptic Membranes
- (2011) G. Beck et al. JOURNAL OF NEUROSCIENCE
- Authentically Phosphorylated -Synuclein at Ser129 Accelerates Neurodegeneration in a Rat Model of Familial Parkinson's Disease
- (2011) H. Sato et al. JOURNAL OF NEUROSCIENCE
- PLA2G6 gene mutation in autosomal recessive early-onset parkinsonism in a Chinese cohort
- (2011) C.- h. Shi et al. NEUROLOGY
- Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
- (2011) A Lemarie et al. ONCOGENE
- Pharmacokinetic evaluation of idebenone
- (2010) Claudia Becker et al. Expert Opinion on Drug Metabolism & Toxicology
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- Succinate dehydrogenase – Assembly, regulation and role in human disease
- (2010) Jared Rutter et al. MITOCHONDRION
- Mitochondrial therapies for Parkinson's disease
- (2010) Bobby Thomas et al. MOVEMENT DISORDERS
- Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
- (2010) H. Mortiboys et al. NEUROLOGY
- Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
- (2010) Shankar J. Chinta et al. NEUROSCIENCE LETTERS
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- DJ-1 binds to mitochondrial complex I and maintains its activity
- (2009) Takuya Hayashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The genetics of Parkinson's syndromes: a critical review
- (2009) John Hardy et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
- (2009) Vanessa A. Morais et al. EMBO Molecular Medicine
- Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1
- (2009) Jeff Blackinton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
- (2009) E. Sidransky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts
- (2008) Heather Mortiboys et al. ANNALS OF NEUROLOGY
- Characterization of PLA2G6 as a locus for dystonia-parkinsonism
- (2008) Coro Paisan-Ruiz et al. ANNALS OF NEUROLOGY
- Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
- (2008) Nelson B. Cole et al. EXPERIMENTAL CELL RESEARCH
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
- Identification of a Novel Protein MICS1 that is Involved in Maintenance of Mitochondrial Morphology and Apoptotic Release of Cytochrome c
- (2008) Toshihiko Oka et al. MOLECULAR BIOLOGY OF THE CELL
- Cytochrome c: functions beyond respiration
- (2008) Yong-Ling P. Ow et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells
- (2008) Shaik Shavali et al. NEUROSCIENCE LETTERS
- ROCO Kinase Activity Is Controlled by Internal GTPase Function
- (2008) B. Weiss Science Signaling
- Complex I deficiency in Parkinson's disease frontal cortex
- (2007) W. Davis Parker et al. BRAIN RESEARCH
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