LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10
出版年份 2019 全文链接
标题
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10
作者
关键词
-
出版物
Autophagy
Volume -, Issue -, Pages 1-20
出版商
Informa UK Limited
发表日期
2019-04-04
DOI
10.1080/15548627.2019.1603548
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson’s disease
- (2019) Fiona Bonello et al. HUMAN MOLECULAR GENETICS
- Endosomal Rab cycles regulate Parkin-mediated mitophagy
- (2018) Koji Yamano et al. eLife
- Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila
- (2018) Tom Cornelissen et al. eLife
- Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
- (2018) Konstantinos Palikaras et al. NATURE CELL BIOLOGY
- Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis
- (2017) Martin Steger et al. eLife
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease
- (2016) Chung-Han Hsieh et al. Cell Stem Cell
- Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
- (2016) Benjamin Richter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
- (2016) Martin Steger et al. eLife
- Cellular functions of Rab GTPases at a glance
- (2015) Y. Zhen et al. JOURNAL OF CELL SCIENCE
- The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
- (2015) Jin-Mi Heo et al. MOLECULAR CELL
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- UDCA exerts beneficial effect on mitochondrial dysfunction inLRRK2G2019Scarriers and in vivo
- (2015) Heather Mortiboys et al. NEUROLOGY
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
- (2014) Agne Kazlauskaite et al. BIOCHEMICAL JOURNAL
- The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
- (2014) Tom Cornelissen et al. HUMAN MOLECULAR GENETICS
- LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity
- (2014) Patricia Gómez-Suaga et al. HUMAN MOLECULAR GENETICS
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- LRRK2 pathobiology in Parkinson's disease
- (2014) Ian Martin et al. JOURNAL OF NEUROCHEMISTRY
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
- (2014) Koji Yamano et al. eLife
- Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation
- (2013) Claudia Manzoni et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Age-related disruption of autophagy in dermal fibroblasts modulates extracellular matrix components
- (2013) Kanae Tashiro et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The current and projected economic burden of Parkinson's disease in the United States
- (2013) Stacey L. Kowal et al. MOVEMENT DISORDERS
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- The ubiquitin ligase parkin mediates resistance to intracellular pathogens
- (2013) Paolo S. Manzanillo et al. NATURE
- The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
- (2013) E. S. Vincow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression
- (2013) Yuangang Zhu et al. Protein & Cell
- Mutant LRRK2 Elicits Calcium Imbalance and Depletion of Dendritic Mitochondria in Neurons
- (2012) Salvatore J. Cherra et al. AMERICAN JOURNAL OF PATHOLOGY
- The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
- (2012) José M. Bravo-San Pedro et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization
- (2012) Tatiana D. Papkovskaia et al. HUMAN MOLECULAR GENETICS
- Rab10 GTPase regulates ER dynamics and morphology
- (2012) Amber R. English et al. NATURE CELL BIOLOGY
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery
- (2011) Hiroyuki Katayama et al. CHEMISTRY & BIOLOGY
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- Parkin Interacts with Ambra1 to Induce Mitophagy
- (2011) C. Van Humbeeck et al. JOURNAL OF NEUROSCIENCE
- What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
- (2011) Olga Corti et al. PHYSIOLOGICAL REVIEWS
- Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
- (2011) P. Wild et al. SCIENCE
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
- (2010) H. Mortiboys et al. NEUROLOGY
- Genomewide Association Study of Leprosy
- (2009) Fu-Ren Zhang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
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