PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling

Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants

(2013) Giovanni Esposito et al.   PLoS Genetics

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

(2012) Andrew W Greene et al.   EMBO REPORTS

Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency

(2012) M. Vos et al.   SCIENCE

The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

(2012) Sven Vilain et al.   PLoS Genetics

Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control

(2011) Derek P. Narendra et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells

(2011) P. Seibler et al.   JOURNAL OF NEUROSCIENCE

Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease

(2011) Andrey Yurevich Abramov et al.   PLoS One

Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

(2011) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

(2010) Derek Narendra et al.   Autophagy

Quinone binding and reduction by respiratory complex I

(2010) Maja A. Tocilescu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Brain Phosphoproteome Obtained by a FASP-Based Method Reveals Plasma Membrane Protein Topology

(2010) Jacek R. Wiśniewski et al.   JOURNAL OF PROTEOME RESEARCH

The architecture of respiratory complex I

(2010) Rouslan G. Efremov et al.   NATURE

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ms_lims, a simple yet powerful open source laboratory information management system for MS-driven proteomics

(2010) Kenny Helsens et al.   PROTEOMICS

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Parkin-induced mitophagy in the pathogenesis of Parkinson disease

(2009) Derek Narendra et al.   Autophagy

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

(2009) Vanessa A. Morais et al.   EMBO Molecular Medicine

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology

(2009) A. Grünewald et al.   EXPERIMENTAL NEUROLOGY

Structural Basis for the Mechanism of Respiratory Complex I

(2009) John M. Berrisford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation

(2009) A. Kathrin Lutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vitroandin VivoProtein-bound Tyrosine Nitration Characterized by Diagonal Chromatography

(2009) Bart Ghesquière et al.   MOLECULAR & CELLULAR PROTEOMICS

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

(2008) C. A. Gautier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

(2008) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

(2008) H. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA