A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
出版年份 2022 全文链接
标题
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
作者
关键词
-
出版物
Cell Reports
Volume 38, Issue 7, Pages 110368
出版商
Elsevier BV
发表日期
2022-01-25
DOI
10.1016/j.celrep.2022.110368
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
- (2021) C. Garrett Rappazzo et al. SCIENCE
- Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
- (2021) Emma S. Winkler et al. CELL
- Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite
- (2021) Gabriele Cerutti et al. Cell Host & Microbe
- Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
- (2021) Kevin R. McCarthy et al. SCIENCE
- Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2
- (2021) Romain Gasser et al. Cell Reports
- The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Janssen COVID-19 Vaccine — United States, February 2021
- (2021) Sara E. Oliver et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein
- (2021) Naveenchandra Suryadevara et al. CELL
- N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2
- (2021) Matthew McCallum et al. CELL
- Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms
- (2021) Yao Sun et al. CELL RESEARCH
- Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial
- (2021) Katherine R W Emary et al. LANCET
- Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
- (2021) William N. Voss et al. SCIENCE
- COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions
- (2021) Opeyemi S. Adeniji et al. mBio
- In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies
- (2021) Dapeng Li et al. CELL
- An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
- (2021) Yafei Liu et al. CELL
- A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses
- (2021) Alexandra Tauzin et al. Cell Host & Microbe
- Humoral and Cellular Immune Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 Variants and Human Coronaviruses After Single BNT162b2 Vaccination
- (2021) Metodi V Stankov et al. CLINICAL INFECTIOUS DISEASES
- Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy
- (2021) Irfan Ullah et al. IMMUNITY
- SARS-CoV-2 variants, spike mutations and immune escape
- (2021) William T. Harvey et al. NATURE REVIEWS MICROBIOLOGY
- Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects
- (2021) Madeleine F. Jennewein et al. Cell Reports
- SARS-CoV-2 Spike Expression at the Surface of Infected Primary Human Airway Epithelial Cells
- (2021) Shilei Ding et al. Viruses-Basel
- Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality
- (2021) Elsa Brunet-Ratnasingham et al. Science Advances
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
- (2020) Xiaolong Tian et al. Emerging Microbes & Infections
- Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies
- (2020) Daniel Wrapp et al. CELL
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- An Infectious cDNA Clone of SARS-CoV-2
- (2020) Xuping Xie et al. Cell Host & Microbe
- Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor
- (2020) Xiangyu Chen et al. Cellular & Molecular Immunology
- Human neutralizing antibodies elicited by SARS-CoV-2 infection
- (2020) Bin Ju et al. NATURE
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- Cell entry mechanisms of SARS-CoV-2
- (2020) Jian Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
- (2020) Yan Wu et al. SCIENCE
- A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
- (2020) Meng Yuan et al. SCIENCE
- A human monoclonal antibody blocking SARS-CoV-2 infection
- (2020) Chunyan Wang et al. Nature Communications
- Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site
- (2020) William D. Tolbert et al. BMC BIOLOGY
- Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells
- (2020) Yunlong Cao et al. CELL
- Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation
- (2020) Emilie Seydoux et al. IMMUNITY
- Convergent antibody responses to SARS-CoV-2 in convalescent individuals
- (2020) Davide F. Robbiani et al. NATURE
- Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
- (2020) Lihong Liu et al. NATURE
- Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections
- (2020) Quan-Xin Long et al. NATURE MEDICINE
- A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
- (2020) Xiangyang Chi et al. SCIENCE
- Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
- (2020) Ching-Lin Hsieh et al. SCIENCE
- SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt, April 2020
- (2020) Daniel C. Payne et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology
- (2020) Luca Piccoli et al. CELL
- Syncytia formation by SARS‐CoV‐2 infected cells
- (2020) Julian Buchrieser et al. EMBO JOURNAL
- Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID19 Patients
- (2020) Larry L. Luchsinger et al. JOURNAL OF CLINICAL MICROBIOLOGY
- UCSF ChimeraX : Structure visualization for researchers, educators, and developers
- (2020) Eric F. Pettersen et al. PROTEIN SCIENCE
- Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
- (2020) M. Alejandra Tortorici et al. SCIENCE
- Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals
- (2020) Guillaume Beaudoin-Bussières et al. mBio
- A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
- (2020) Xuping Xie et al. Nature Communications
- Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China
- (2020) Fan Wu et al. JAMA Internal Medicine
- The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens
- (2020) Liangwei Duan et al. Frontiers in Immunology
- Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality
- (2020) Tomer Zohar et al. CELL
- Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles
- (2020) Maolin Lu et al. Cell Host & Microbe
- Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
- (2020) Alexandra Schäfer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
- (2020) Merryn Voysey et al. LANCET
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
- (2020) Lindsey R. Baden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Moderna COVID-19 Vaccine — United States, December 2020
- (2020) Sara E. Oliver et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Structural Basis for Epitopes in the gp120 Cluster A Region that Invokes Potent Effector Cell Activity
- (2019) William Tolbert et al. Viruses-Basel
- Conceptual Approaches to Modulating Antibody Effector Functions and Circulation Half-Life
- (2019) Kevin O. Saunders Frontiers in Immunology
- Differential requirements for FcγR engagement by protective antibodies against Ebola virus
- (2019) Stylianos Bournazos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- New tools for automated high-resolution cryo-EM structure determination in RELION-3
- (2018) Jasenko Zivanov et al. eLife
- A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
- (2018) Jasenko Zivanov et al. IUCrJ
- Affinity of human IgG subclasses to mouse Fc gamma receptors
- (2017) Gillian Dekkers et al. mAbs
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- Recent developments in the CCP-EM software suite
- (2017) Tom Burnley et al. Acta Crystallographica Section D-Structural Biology
- SAbPred: a structure-based antibody prediction server
- (2016) James Dunbar et al. NUCLEIC ACIDS RESEARCH
- Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect
- (2015) David J. DiLillo et al. CELL
- Alignment of cryo-EM movies of individual particles by optimization of image translations
- (2015) John L. Rubinstein et al. JOURNAL OF STRUCTURAL BIOLOGY
- EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
- (2015) Benjamin A Barad et al. NATURE METHODS
- Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity
- (2014) Stylianos Bournazos et al. CELL
- Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection
- (2014) P. Acharya et al. JOURNAL OF VIROLOGY
- Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo
- (2014) David J DiLillo et al. NATURE MEDICINE
- Prevention of overfitting in cryo-EM structure determination
- (2012) Sjors H W Scheres et al. NATURE METHODS
- Mouse model recapitulating human Fc receptor structural and functional diversity
- (2012) P. Smith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells
- (2008) J. O. Richards et al. MOLECULAR CANCER THERAPEUTICS
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