Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation

Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significance

(2021) Scott Ayton et al.   Alzheimers & Dementia

Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease

(2021) Wen-Dai Bao et al.   CELL DEATH AND DIFFERENTIATION

Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathway

(2021) Ming‐hao Ge et al.   CNS Neuroscience & Therapeutics

Ginsenoside Rh1 Induces MCF-7 Cell Apoptosis and Autophagic Cell Death through ROS-Mediated Akt Signaling

(2021) Diem Thi Ngoc Huynh et al.   Cancers

Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62–Keap1–Nrf2 Pathway

(2021) Yanan Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Naringin Chelates Excessive Iron and Prevents the Formation of Amyloid-Beta Plaques in the Hippocampus of Iron-Overloaded Mice

(2021) Mehrdad Jahanshahi et al.   Frontiers in Pharmacology

The lncRNA TEX41 is upregulated in pediatric B-Cells Acute Lymphoblastic Leukemia and it is necessary for leukemic cell growth

(2021) Francesca Maria Orlandella et al.   Biomarker Research

Breviscapine exerts neuroprotective effects through multiple mechanisms in APP/PS1 transgenic mice

(2020) Zhu Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

VDR activation attenuate cisplatin induced AKI by inhibiting ferroptosis

(2020) Zhaoxin Hu et al.   Cell Death & Disease

Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma Cells via PI3K/Akt/NF-κB Signaling Pathway

(2020) Wenjun Li et al.   Frontiers in Pharmacology

20(S)-protopanaxadiol and oleanolic acid ameliorate cognitive deficits in APP/PS1 transgenic mice by enhancing hippocampal neurogenesis

(2020) Kaili Lin et al.   Journal of Ginseng Research

Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro

(2020) Bo Ding et al.   Journal of Neuroinflammation

Activated PKB/GSK-3β synergizes with PKC-δ signaling in attenuating myocardial ischemia/reperfusion injury via potentiation of NRF2 activity: therapeutic efficacy of dihydrotanshinone-I

(2020) Hao Zeng et al.   Acta Pharmaceutica Sinica B

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Sodium rutin ameliorates Alzheimer’s disease–like pathology by enhancing microglial amyloid-β clearance

(2019) Rui-Yuan Pan et al.   Science Advances

Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review

(2019) Pengxu Lei et al.   Frontiers in Physiology

The Induction of Ferroptosis by Impairing STAT3/Nrf2/GPx4 Signaling Enhances the Sensitivity of Osteosarcoma Cells to Cisplatin

(2019) Qiang Liu et al.   CELL BIOLOGY INTERNATIONAL

1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling

(2019) Lulu Chen et al.   AGING CELL

Ginseng metabolite Protopanaxadiol induces Sestrin2 expression and AMPK activation through GCN2 and PERK

(2019) Hong Ri Jin et al.   Cell Death & Disease

c‐Myb Promotes Growth and Metastasis of Colorectal Cancer Through c‐fos induced Epithelial mesenchymal transformation

(2019) Xiao Qu et al.   CANCER SCIENCE

Eriodictyol alleviates lipopolysaccharide‐triggered oxidative stress and synaptic dysfunctions in BV‐2 microglial cells and mouse brain

(2019) Pandi He et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Eriodictyol inhibits high glucose‐induced extracellular matrix accumulation, oxidative stress, and inflammation in human glomerular mesangial cells

(2019) Jin Bai et al.   PHYTOTHERAPY RESEARCH

Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress

(2019) Jude Prah et al.   BRAIN RESEARCH

Eriodictyol ameliorates lipopolysaccharide‐induced acute lung injury by suppressing the inflammatory COX‐2/NLRP3/NF‐κB pathway in mice

(2019) Xia Wang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease

(2019) Md. Sahab Uddin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer

(2019) Site Yu et al.   Cell Death & Disease

SIRT3-mediated deacetylation of PRDX3 alleviates mitochondrial oxidative damage and apoptosis induced by intestinal ischemia/reperfusion injury

(2019) Zhanyu Wang et al.   Redox Biology

Why should neuroscientists worry about iron? The emerging role of ferroptosis in the pathophysiology of neuroprogressive diseases

(2018) Gerwyn Morris et al.   BEHAVIOURAL BRAIN RESEARCH

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

(2018) Moataz Abdalkader et al.   Frontiers in Neuroscience

Role of GPX4 in ferroptosis and its pharmacological implication

(2018) Tobias M. Seibt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Striking while the iron is hot: Iron metabolism and Ferroptosis in neurodegeneration

(2018) Shashank Masaldan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Eriodictyol Attenuates LPS-Induced Neuroinflammation, Amyloidogenesis, and Cognitive Impairments via the Inhibition of NF-κB in Male C57BL/6J Mice and BV2 Microglial Cells

(2018) Pandi He et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Overexpression of Human Wild-Type Amyloid-β Protein Precursor Decreases the Iron Content and Increases the Oxidative Stress of Neuroblastoma SH-SY5Y Cells

(2018) Li Wan et al.   JOURNAL OF ALZHEIMERS DISEASE

Perturbed Iron Distribution in Alzheimer's Disease Serum, Cerebrospinal Fluid, and Selected Brain Regions: A Systematic Review and Meta-Analysis

(2018) Yunlong Tao et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglial activation occurs late during preclinical Alzheimer's disease

(2018) Wolfgang J. Streit et al.   GLIA

Eriodictyol inhibits high glucose-induced oxidative stress and inflammation in retinal ganglial cells

(2018) Peilin Lv et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ferroptosis and Its Role in Diverse Brain Diseases

(2018) Abigail Weiland et al.   MOLECULAR NEUROBIOLOGY

Protective effects of tanshinone IIA on SH-SY5Y cells against oAβ1–42-induced apoptosis due to prevention of endoplasmic reticulum stress

(2018) Weina Yang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in animal model of Alzheimer’s disease

(2018) Syed Obaidur Rahman et al.   BIOMEDICINE & PHARMACOTHERAPY

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

(2017) Delin Chen et al.   MOLECULAR CELL

Eriodictyol, Not Its Glucuronide Metabolites, Attenuates Acetaminophen-Induced Hepatotoxicity

(2017) Zhaoyu Wang et al.   MOLECULAR PHARMACEUTICS

Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis

(2017) Z Fan et al.   Oncogenesis

Neuroprotective action of N-acetyl serotonin in oxidative stress-induced apoptosis through the activation of both TrkB/CREB/BDNF pathway and Akt/Nrf2/Antioxidant enzyme in neuronal cells

(2017) Jae-Myung Yoo et al.   Redox Biology

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1ΔE9 transgenic mice

(2016) Jian-Hui Wang et al.   Alzheimers Research & Therapy

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

(2015) Xiaofang Sun et al.   HEPATOLOGY

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

(2015) Liuji Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

R2* mapping for brain iron: associations with cognition in normal aging

(2015) Christine Ghadery et al.   NEUROBIOLOGY OF AGING

Eriodictyol Attenuates β-Amyloid 25–35 Peptide-Induced Oxidative Cell Death in Primary Cultured Neurons by Activation of Nrf2

(2015) Xu Jing et al.   NEUROCHEMICAL RESEARCH

Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits

(2015) Shu-Sheng Jiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding model for eriodictyol to Jun-N terminal kinase and its anti-inflammatory signaling pathway

(2014) Eunjung Lee et al.   BMB Reports

sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin

(2014) R. C. McCarthy et al.   EMBO REPORTS

The role of iron in brain ageing and neurodegenerative disorders

(2014) Roberta J Ward et al.   LANCET NEUROLOGY

β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

(2014) Bruce X. Wong et al.   PLoS One

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Roles of the amyloid precursor protein family in the peripheral nervous system

(2012) John H. Caldwell et al.   MECHANISMS OF DEVELOPMENT

MRI estimates of brain iron concentration in normal aging using quantitative susceptibility mapping

(2011) Berkin Bilgic et al.   NEUROIMAGE

MRI estimates of brain iron concentration in normal aging: Comparison of field-dependent (FDRI) and phase (SWI) methods

(2009) Adolf Pfefferbaum et al.   NEUROIMAGE

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism