标题
RNA demethylase ALKBH5 in cancer: from mechanisms to therapeutic potential
作者
关键词
-
出版物
Journal of Hematology & Oncology
Volume 15, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-01-21
DOI
10.1186/s13045-022-01224-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- ALKBH5-mediated m6A demethylation of FOXM1 mRNA promotes progression of uveal melanoma
- (2021) Lili Hao et al. Aging-US
- ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma
- (2021) Ye Yuan et al. Cell Death & Disease
- EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma
- (2021) Runping Fang et al. Nature Communications
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Expression and molecular profiles of the AlkB family in ovarian serous carcinoma
- (2021) Yuan Cai et al. Aging-US
- Circular RNA circZbtb20 maintains ILC3 homeostasis and function via Alkbh5-dependent m6A demethylation of Nr4a1 mRNA
- (2021) Benyu Liu et al. Cellular & Molecular Immunology
- ALKBH5-mediated m6A demethylation of lncRNA RMRP plays an oncogenic role in lung adenocarcinoma
- (2021) Hui Yu et al. MAMMALIAN GENOME
- Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
- (2021) Eliza Yankova et al. NATURE
- miRNA-193a-3p Regulates the AKT2 Pathway to Inhibit the Growth and Promote the Apoptosis of Glioma Cells by Targeting ALKBH5
- (2021) Yong Cui et al. Frontiers in Oncology
- Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors
- (2021) Simona Selberg et al. ACS Omega
- A positive-feedback loop between HBx and ALKBH5 promotes hepatocellular carcinogenesis
- (2021) Siming Qu et al. BMC CANCER
- M6A Demethylase ALKBH5 Regulates PD-L1 Expression and Tumor Immunoenvironment in Intrahepatic Cholangiocarcinoma
- (2021) Xinyao Qiu et al. CANCER RESEARCH
- The RNA demethylase ALKBH5 promotes osteoblast differentiation by modulating Runx2 mRNA stability
- (2021) Lingling Feng et al. FEBS LETTERS
- YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma
- (2021) Rui-Chao Chai et al. Journal of Hematology & Oncology
- m6A demethylase ALKBH5 suppresses proliferation and migration of enteric neural crest cells by regulating TAGLN in Hirschsprung's disease
- (2021) Binyu Wang et al. LIFE SCIENCES
- ALKBH5 Promotes the Proliferation of Glioma Cells via Enhancing the mRNA Stability of G6PD
- (2021) Zhifeng Liu et al. NEUROCHEMICAL RESEARCH
- Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response
- (2021) Fang Yu et al. NUCLEIC ACIDS RESEARCH
- Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer
- (2021) Donghong Zhang et al. Cell Death & Disease
- N6-methyladenosine binding induces a metal-centered rearrangement that activates the human RNA demethylase Alkbh5
- (2021) Jeffrey A. Purslow et al. Science Advances
- m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity
- (2021) Jing Zhou et al. Science Advances
- ALKBH5 Facilitates Hypoxia-Induced Paraspeckle Assembly and IL8 Secretion to Generate an Immunosuppressive Tumor Microenvironment
- (2021) Feng Dong et al. CANCER RESEARCH
- Hallmarks of response, resistance, and toxicity to immune checkpoint blockade
- (2021) Golnaz Morad et al. CELL
- ALKBH5-Modified HMGB1-STING Activation Contributes to Radiation Induced Liver Disease via Innate Immune Response
- (2021) Genwen Chen et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- ALKBH5-mediated m6A mRNA methylation governs human embryonic stem cell cardiac commitment
- (2021) Zhenbo Han et al. Molecular Therapy-Nucleic Acids
- DDX3 modulates cisplatin resistance in OSCC through ALKBH5-mediated m6A-demethylation of FOXM1 and NANOG
- (2020) Omprakash Shriwas et al. APOPTOSIS
- The N 6 -methyladenosine (m6 A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity-associated protein (FTO) are prognostic biomarkers in patients with clear cell renal carcinoma
- (2020) Alexander Strick et al. BJU INTERNATIONAL
- BMP2 Modified by the m6A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway
- (2020) Hai-Feng Wang et al. CALCIFIED TISSUE INTERNATIONAL
- ALKBH5-mediated m6A demethylation of lncRNA PVT1 plays an oncogenic role in osteosarcoma
- (2020) Shuo Chen et al. Cancer Cell International
- N6-methyladenosine ALKBH5 promotes non-small cell lung cancer progress by regulating TIMP3 stability
- (2020) Zhiyuan Zhu et al. GENE
- KIAA1429 regulates cell proliferation by targeting c‐Jun messenger RNA directly in gastric cancer
- (2020) Ran Miao et al. JOURNAL OF CELLULAR PHYSIOLOGY
- m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling
- (2020) Bo Tang et al. Molecular Cancer
- m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2–mediated YAP activity in NSCLC
- (2020) Dan Jin et al. Molecular Cancer
- Engineering adeno-associated virus vectors for gene therapy
- (2020) Chengwen Li et al. NATURE REVIEWS GENETICS
- Cancer immunotherapy: Pros, cons and beyond
- (2020) Shuzhen Tan et al. BIOMEDICINE & PHARMACOTHERAPY
- m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
- (2020) Huilin Huang et al. CANCER CELL
- Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
- (2020) Jiazhen Wang et al. Cell Stem Cell
- RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
- (2020) Chao Shen et al. Cell Stem Cell
- Small‐Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer
- (2020) Rajiv K. Bedi et al. ChemMedChem
- m 6 A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis
- (2020) Yushi Nagaki et al. GENES TO CELLS
- RNA demethylase ALKBH5 promotes ovarian carcinogenesis in a simulated tumour microenvironment through stimulating NF‐ κ B pathway
- (2020) Yi Jiang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner
- (2020) Xingya Guo et al. Molecular Cancer
- Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein
- (2020) Jiexin Li et al. NUCLEIC ACIDS RESEARCH
- PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
- (2020) Sajid Khan et al. ONCOGENE
- LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma
- (2020) Boyang Liu et al. Cell Death & Disease
- Identification of m6A-related genes and m6A RNA methylation regulators in pancreatic cancer and their association with survival
- (2020) Yan Geng et al. Annals of Translational Medicine
- ALKBH5 promotes the proliferation of renal cell carcinoma by regulating AURKB expression in an m6A-dependent manner
- (2020) Xiaolei Zhang et al. Annals of Translational Medicine
- ALKBH5 suppresses malignancy of hepatocellular carcinoma via m6A-guided epigenetic inhibition of LYPD1
- (2020) Yunhao Chen et al. Molecular Cancer
- Programmable m6A modification of cellular RNAs with a Cas13-directed methyltransferase
- (2020) Christopher Wilson et al. NATURE BIOTECHNOLOGY
- ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment
- (2020) Na Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA demethylase Alkbh5 is widely expressed in neurons and decreased during brain development
- (2020) Tingfu Du et al. BRAIN RESEARCH BULLETIN
- CRISPR/Cas9: A preclinical and clinical perspective for the treatment of human diseases
- (2020) Garima Sharma et al. MOLECULAR THERAPY
- The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
- (2020) Deobrat Dixit et al. Cancer Discovery
- ALKBH5 inhibited cell proliferation and sensitized bladder cancer cells to cisplatin by m6A-CK2α mediated glycolysis
- (2020) Hao Yu et al. Molecular Therapy-Nucleic Acids
- Hypoxia induces an endometrial cancer stem-like cell phenotype via HIF-dependent demethylation of SOX2 mRNA
- (2020) Guofang Chen et al. Oncogenesis
- A positive feedback loop between AlkB homolog 5 and miR-193a-3p promotes growth and metastasis in esophageal squamous cell carcinoma
- (2020) Jinliang Xue et al. Human Cell
- The m6A RNA Demethylase ALKBH5 Promotes Radioresistance and Invasion Capability of Glioma Stem Cells
- (2020) Aline Kowalski-Chauvel et al. Cancers
- HIF Inhibitors: Status of Current Clinical Development
- (2019) Jaleh Fallah et al. Current Oncology Reports
- Identification of Flavin Mononucleotide as a Cell-Active Artificial N 6 -Methyladenosine RNA Demethylase
- (2019) Li-Jun Xie et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Changes of N6-methyladenosine modulators promote breast cancer progression
- (2019) Lianpin Wu et al. BMC CANCER
- Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
- (2019) Yue Huang et al. CANCER CELL
- ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2
- (2019) Hongtao Zhu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- HDAC6 inhibition synergizes with anti-PD-L1 therapy in ARID1A-inactivated ovarian cancer.
- (2019) Takeshi Fukumoto et al. CANCER RESEARCH
- ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1
- (2019) Jun Zhang et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- KIAA1429 acts as an oncogenic factor in breast cancer by regulating CDK1 in an N6-methyladenosine-independent manner
- (2019) Jia-Yi Qian et al. ONCOGENE
- HBx protein contributes to liver carcinogenesis by H3K4me3 modification through stabilizing WD repeat domain 5 protein
- (2019) Weiwu Gao et al. HEPATOLOGY
- ALKBH5 Holds Prognostic Values and Inhibits the Metastasis of Colon Cancer
- (2019) Peipei Yang et al. PATHOLOGY & ONCOLOGY RESEARCH
- N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer
- (2019) Huan Jin et al. EBioMedicine
- The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling
- (2019) Jinjin Yu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG
- (2019) Katherine I. Zhou et al. MOLECULAR CELL
- N6-Methyladenosine Modification Controls Circular RNA Immunity
- (2019) Y. Grace Chen et al. MOLECULAR CELL
- Breast Cancer Stem Cells as Drivers of Tumor Chemoresistance, Dormancy and Relapse: New Challenges and Therapeutic Opportunities
- (2019) De Angelis et al. Cancers
- ALKBH5-m6A-FOXM1 signaling axis promotes proliferation and invasion of lung adenocarcinoma cells under intermittent hypoxia
- (2019) Yinghui Chao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- 3D proteome-wide scale screening and activity evaluation of a new ALKBH5 inhibitor in U87 glioblastoma cell line
- (2019) Alessio Malacrida et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Targeting Epigenetics in Cancer
- (2018) Richard L. Bennett et al. Annual Review of Pharmacology and Toxicology
- Ovarian cancer statistics, 2018
- (2018) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Emerging roles of long non-coding RNA in cancer
- (2018) Anna Sanchez Calle et al. CANCER SCIENCE
- The Human Transcription Factors
- (2018) Samuel A. Lambert et al. CELL
- R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling
- (2018) Rui Su et al. CELL
- METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification
- (2018) Hengyou Weng et al. Cell Stem Cell
- ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation
- (2018) Yuan He et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d
- (2018) Philip Knuckles et al. GENES & DEVELOPMENT
- Regulation and Function of the PD-L1 Checkpoint
- (2018) Chong Sun et al. IMMUNITY
- Zc3h13 Regulates Nuclear RNA m 6 A Methylation and Mouse Embryonic Stem Cell Self-Renewal
- (2018) Jing Wen et al. MOLECULAR CELL
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- N 6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential
- (2018) Dandan Yang et al. NUCLEIC ACIDS RESEARCH
- Gene therapy comes of age
- (2018) Cynthia E. Dunbar et al. SCIENCE
- Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression
- (2018) Jiwei Guo et al. Oncogenesis
- VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
- (2018) Yanan Yue et al. Cell Discovery
- METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition
- (2018) Wenfeng Hua et al. GYNECOLOGIC ONCOLOGY
- Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances
- (2018) Alphonse E. Sirica et al. HEPATOLOGY
- Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
- (2018) Jiangbo Wei et al. MOLECULAR CELL
- mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis
- (2018) Junho Choe et al. NATURE
- Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
- (2018) Thomas Treiber et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression
- (2018) Nate J. Fry et al. Oncotarget
- RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β
- (2018) Rosa M. Rubio et al. GENES & DEVELOPMENT
- Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia
- (2017) Chau-To Kwok et al. Journal of Hematology & Oncology
- Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
- (2017) Isaia Barbieri et al. NATURE
- RNA targeting with CRISPR–Cas13
- (2017) Omar O. Abudayyeh et al. NATURE
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- RMBase v2.0: deciphering the map of RNA modifications from epitranscriptome sequencing data
- (2017) Jia-Jia Xuan et al. NUCLEIC ACIDS RESEARCH
- N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein
- (2017) Nian Liu et al. NUCLEIC ACIDS RESEARCH
- MODOMICS: a database of RNA modification pathways. 2017 update
- (2017) Pietro Boccaletto et al. NUCLEIC ACIDS RESEARCH
- ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells
- (2017) Chong Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer
- (2017) Xiuli Wang et al. Oncotarget
- Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs
- (2017) Chan Zhou et al. Cell Reports
- YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
- (2017) Ian A Roundtree et al. eLife
- The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5
- (2017) Abdullah Shah et al. Stem Cells International
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- Adeno-associated virus (AAV) vectors in cancer gene therapy
- (2016) Jorge L. Santiago-Ortiz et al. JOURNAL OF CONTROLLED RELEASE
- Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing
- (2016) Wen Xiao et al. MOLECULAR CELL
- The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
- (2016) Shuibin Lin et al. MOLECULAR CELL
- LKB1 loss links serine metabolism to DNA methylation and tumorigenesis
- (2016) Filippos Kottakis et al. NATURE
- m6A RNA methylation promotes XIST-mediated transcriptional repression
- (2016) Deepak P. Patil et al. NATURE
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
- (2016) Chuanzhao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
- (2016) Omar O. Abudayyeh et al. SCIENCE
- YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex
- (2016) Hao Du et al. Nature Communications
- Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
- (2016) Chuanzhao Zhang et al. Oncotarget
- 5′ UTR m6A Promotes Cap-Independent Translation
- (2015) Kate D. Meyer et al. CELL
- Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
- (2015) Fa-Xing Yu et al. CELL
- HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
- (2015) Claudio R. Alarcón et al. CELL
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency
- (2015) Xiao Wang et al. CELL
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- N6-methyladenosine marks primary microRNAs for processing
- (2015) Claudio R. Alarcón et al. NATURE
- N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
- (2015) Nian Liu et al. NATURE
- Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
- (2015) Bastian Linder et al. NATURE METHODS
- Acute Myeloid Leukemia
- (2015) Hartmut Döhner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities
- (2015) F. Skoulidis et al. Cancer Discovery
- Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
- (2014) Xiao-Li Ping et al. CELL RESEARCH
- Targeting Tumor Suppressor p53 for Cancer Therapy: Strategies, Challenges and Opportunities
- (2014) Bo Hong et al. CURRENT DRUG TARGETS
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-strandedN6-Methyladenosine RNA Demethylation
- (2014) Chao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition
- (2014) Chong Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
- (2014) Yang Wang et al. NATURE CELL BIOLOGY
- Gene expression regulation mediated through reversible m6A RNA methylation
- (2014) Ye Fu et al. NATURE REVIEWS GENETICS
- Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation
- (2014) WeiShen Aik et al. NUCLEIC ACIDS RESEARCH
- Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5
- (2014) Yue Huang et al. NUCLEIC ACIDS RESEARCH
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
- (2014) Schraga Schwartz et al. Cell Reports
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
- (2013) Jianzhao Liu et al. Nature Chemical Biology
- CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010
- (2013) Q. T. Ostrom et al. NEURO-ONCOLOGY
- Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA
- (2013) N. Liu et al. RNA
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Protein Arginine Methyltransferase 7 Regulates Cellular Response to DNA Damage by Methylating Promoter Histones H2A and H4 of the Polymerase δ Catalytic Subunit Gene,POLD1
- (2012) Vrajesh Karkhanis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase
- (2012) Esther C. Y. Woon et al. JOURNAL OF MEDICINAL CHEMISTRY
- The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts
- (2012) Alexander G. Baltz et al. MOLECULAR CELL
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
- (2012) Laurens Kruidenier et al. NATURE
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- Genetics of adult glioma
- (2012) McKinsey L. Goodenberger et al. Cancer Genetics
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
- (2011) Armin Thalhammer et al. PLoS One
- Epigenetic modifications and human disease
- (2010) Anna Portela et al. NATURE BIOTECHNOLOGY
- Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
- (2008) Guifang Jia et al. FEBS LETTERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search