Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation
出版年份 2014 全文链接
标题
Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation
作者
关键词
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出版物
NUCLEIC ACIDS RESEARCH
Volume 42, Issue 7, Pages 4741-4754
出版商
Oxford University Press (OUP)
发表日期
2014-02-01
DOI
10.1093/nar/gku085
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- (2013) Rasheduzzaman Chowdhury et al. ACS Chemical Biology
- Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation
- (2013) Lulu Hu et al. CELL
- Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)
- (2013) WeiShen Aik et al. JOURNAL OF MEDICINAL CHEMISTRY
- 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
- (2013) Richard J. Hopkinson et al. Chemical Science
- Mapping and significance of the mRNA methylome
- (2013) Tennille Sibbritt et al. Wiley Interdisciplinary Reviews-RNA
- Structure and Function of Noncanonical Nucleobases
- (2012) Thomas Carell et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases
- (2012) WeiShen Aik et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity
- (2012) Hanne Korvald et al. DNA REPAIR
- Development of Cell-Active N6-Methyladenosine RNA Demethylase FTO Inhibitor
- (2012) Baoen Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- Duplex interrogation by a direct DNA repair protein in search of base damage
- (2012) Chengqi Yi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- MODOMICS: a database of RNA modification pathways—2013 update
- (2012) Magdalena A. Machnicka et al. NUCLEIC ACIDS RESEARCH
- N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB
- (2012) P. Van Damme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reversible RNA adenosine methylation in biological regulation
- (2012) Guifang Jia et al. TRENDS IN GENETICS
- Inhibition of 2-oxoglutarate dependent oxygenases
- (2011) Nathan R. Rose et al. CHEMICAL SOCIETY REVIEWS
- Methylsulfonylnitrobenzoates, a New Class of Irreversible Inhibitors of the Interaction of the Thyroid Hormone Receptor and Its Obligate Coactivators That Functionally Antagonizes Thyroid Hormone
- (2011) Jong Yeon Hwang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure and RNA Binding Properties of the RNA Recognition Motif (RRM) and AlkB Domains in Human AlkB Homolog 8 (ABH8), an Enzyme Catalyzing tRNA Hypermodification
- (2011) Chiara Pastore et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
- (2011) Armin Thalhammer et al. PLoS One
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The AlkB Domain of Mammalian ABH8 Catalyzes Hydroxylation of 5-Methoxycarbonylmethyluridine at the Wobble Position of tRNA
- (2010) Ye Fu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structural studies on human 2-oxoglutarate dependent oxygenases
- (2010) Michael A McDonough et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia
- (2010) Lin Yan et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Small-Molecule-Based Inhibition of Histone Demethylation in Cells Assessed by Quantitative Mass Spectrometry
- (2010) Mukram M. Mackeen et al. JOURNAL OF PROTEOME RESEARCH
- Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding
- (2010) L. Songe-Moller et al. MOLECULAR AND CELLULAR BIOLOGY
- Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase
- (2010) Chengqi Yi et al. NATURE
- Crystal structure of the FTO protein reveals basis for its substrate specificity
- (2010) Zhifu Han et al. NATURE
- Origin and evolution of peptide-modifying dioxygenases and identification of the wybutosine hydroxylase/hydroperoxidase
- (2010) L. M. Iyer et al. NUCLEIC ACIDS RESEARCH
- The RNA modification database, RNAMDB: 2011 update
- (2010) W. A. Cantara et al. NUCLEIC ACIDS RESEARCH
- Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification
- (2010) Megumi Kato et al. NUCLEIC ACIDS RESEARCH
- Structural and Mutational Analysis of Escherichia coli AlkB Provides Insight into Substrate Specificity and DNA Damage Searching
- (2010) Paul J. Holland et al. PLoS One
- Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
- (2010) Christoph Loenarz et al. TRENDS IN BIOCHEMICAL SCIENCES
- Lys-N and Trypsin Cover Complementary Parts of the Phosphoproteome in a Refined SCX-Based Approach
- (2009) Sharon Gauci et al. ANALYTICAL CHEMISTRY
- Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites
- (2009) Tina A. Müller et al. DNA REPAIR
- Different Modes of Inhibitor Binding to Prolyl Hydroxylase by Combined Use of X-ray Crystallography and NMR Spectroscopy of Paramagnetic Complexes
- (2009) Leszek Poppe et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB
- (2009) B. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
- (2009) C. Choudhary et al. SCIENCE
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- Quantitative Phosphoproteomic Analysis of T Cell Receptor Signaling Reveals System-Wide Modulation of Protein-Protein Interactions
- (2009) V. Mayya et al. Science Signaling
- The SR protein family
- (2009) Peter J Shepard et al. GENOME BIOLOGY
- Evidence That Two Enzyme-derived Histidine Ligands Are Sufficient for Iron Binding and Catalysis by Factor Inhibiting HIF (FIH)
- (2008) Kirsty S. Hewitson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improved Description of Nuclear Magnetic Resonance Chemical Shielding Constants Using the M06-L Meta-Generalized-Gradient-Approximation Density Functional
- (2008) Yan Zhao et al. JOURNAL OF PHYSICAL CHEMISTRY A
- Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
- (2008) Cai-Guang Yang et al. NATURE
- A quantitative atlas of mitotic phosphorylation
- (2008) N. Dephoure et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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