标题
Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5
作者
关键词
-
出版物
NUCLEIC ACIDS RESEARCH
Volume 43, Issue 1, Pages 373-384
出版商
Oxford University Press (OUP)
发表日期
2014-12-02
DOI
10.1093/nar/gku1276
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Synthesis of a FTO Inhibitor with Anticonvulsant Activity
- (2014) Guanqun Zheng et al. ACS Chemical Neuroscience
- Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues
- (2014) Chenxu Zhu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mechanism and Function of Oxidative Reversal of DNA and RNA Methylation
- (2014) Li Shen et al. Annual Review of Biochemistry
- Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
- (2014) Xiao-Li Ping et al. CELL RESEARCH
- FTO and Obesity: Mechanisms of Association
- (2014) Xu Zhao et al. Current Diabetes Reports
- Crystal structure of the RNA demethylase ALKBH5 from zebrafish
- (2014) Weizhong Chen et al. FEBS LETTERS
- Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-strandedN6-Methyladenosine RNA Demethylation
- (2014) Chao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition
- (2014) Chong Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation
- (2014) WeiShen Aik et al. NUCLEIC ACIDS RESEARCH
- High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
- (2013) Schraga Schwartz et al. CELL
- Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)
- (2013) WeiShen Aik et al. JOURNAL OF MEDICINAL CHEMISTRY
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
- (2013) Jianzhao Liu et al. Nature Chemical Biology
- The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of β-hairpin
- (2013) BaoEn Chen et al. Science China-Chemistry
- Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases
- (2012) Esther C. Y. Woon et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase
- (2012) Esther C. Y. Woon et al. JOURNAL OF MEDICINAL CHEMISTRY
- Exocyclic Carbons Adjacent to the N6 of Adenine are Targets for Oxidation by the Escherichia coli Adaptive Response Protein AlkB
- (2012) Deyu Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Development of Cell-Active N6-Methyladenosine RNA Demethylase FTO Inhibitor
- (2012) Baoen Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
- (2012) Laurens Kruidenier et al. NATURE
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- Duplex interrogation by a direct DNA repair protein in search of base damage
- (2012) Chengqi Yi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Reversible RNA adenosine methylation in biological regulation
- (2012) Guifang Jia et al. TRENDS IN GENETICS
- N6-methyl-adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function
- (2012) Yamei Niu et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- The role of the fat mass and obesity associated gene (FTO) in breast cancer risk
- (2011) Virginia Kaklamani et al. BMC Medical Genetics
- Inhibition of 2-oxoglutarate dependent oxygenases
- (2011) Nathan R. Rose et al. CHEMICAL SOCIETY REVIEWS
- Synthesis, crystal structures and spectroscopy of meclofenamic acid and its metal complexes with manganese(II), copper(II), zinc(II) and cadmium(II). Antiproliferative and superoxide dismutase activity
- (2011) Dimitra Kovala-Demertzi et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- A Selective Inhibitor and Probe of the Cellular Functions of Jumonji C Domain-Containing Histone Demethylases
- (2011) Xuelai Luo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- The AlkB Domain of Mammalian ABH8 Catalyzes Hydroxylation of 5-Methoxycarbonylmethyluridine at the Wobble Position of tRNA
- (2010) Ye Fu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mechanistic insight into the recognition of single-stranded and double-stranded DNA substrates by ABH2 and ABH3
- (2010) Baoen Chen et al. Molecular BioSystems
- Crystal structure of the FTO protein reveals basis for its substrate specificity
- (2010) Zhifu Han et al. NATURE
- Grand Challenge Commentary: RNA epigenetics?
- (2010) Chuan He Nature Chemical Biology
- A Common Variant of the FTO Gene Is Associated With Not Only Increased Adiposity but Also Elevated Blood Pressure in French Canadians
- (2009) Zdenka Pausova et al. Circulation-Cardiovascular Genetics
- Association of FTO gene with hyperandrogenemia and metabolic parameters in women with polycystic ovary syndrome
- (2009) Elisabeth Wehr et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Inactivation of the Fto gene protects from obesity
- (2009) Julia Fischer et al. NATURE
- Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
- (2008) Guifang Jia et al. FEBS LETTERS
- Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
- (2008) Cai-Guang Yang et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search