标题
Drug repurposing against SARS-CoV-1, SARS-CoV-2 and MERS-CoV
作者
关键词
-
出版物
Future Microbiology
Volume 16, Issue 17, Pages 1341-1370
出版商
Future Medicine Ltd
发表日期
2021-11-10
DOI
10.2217/fmb-2021-0019
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials
- (2021) Kimberley Lewis et al. PLoS One
- Darunavir/cobicistat is associated with negative outcomes in HIV-negative patients with severe COVID-19 pneumonia
- (2021) Jovana Milic et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Use of hydroxychloroquine and chloroquine in patients with COVID-19: a meta-analysis of randomized clinical trials
- (2021) Paulo Roberto Bignardi et al. Pathogens and Global Health
- Ivermectin for Prevention and Treatment of COVID-19 Infection
- (2021) Andrew Bryant et al. AMERICAN JOURNAL OF THERAPEUTICS
- The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials
- (2021) Soheil Hassanipour et al. Scientific Reports
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
- (2020) Manli Wang et al. CELL RESEARCH
- Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
- (2020) Timothy P. Sheahan et al. Nature Communications
- Hydroxychloroquine or Chloroquine for Treatment or Prophylaxis of COVID-19: A Living Systematic Review
- (2020) Adrian V. Hernandez et al. ANNALS OF INTERNAL MEDICINE
- Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
- (2020) Sangeun Jeon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus-related coronavirus model
- (2020) Hua-Hao Fan et al. CHINESE MEDICAL JOURNAL
- In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
- (2020) Xueting Yao et al. CLINICAL INFECTIOUS DISEASES
- Umifenovir treatment is not associated with improved outcomes in patients with coronavirus disease 2019: a retrospective study
- (2020) N. Lian et al. CLINICAL MICROBIOLOGY AND INFECTION
- Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal
- (2020) Jacques Fantini et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Arbidol: A potential antiviral drug for the treatment of SARS-CoV-2 by blocking trimerization of the spike glycoprotein
- (2020) Naveen Vankadari INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection
- (2020) Jacques Fantini et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- (2020) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Lack of Antiviral Activity of Darunavir against SARS-CoV-2
- (2020) Sandra De Meyer et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency
- (2020) Calvin J. Gordon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The anti‐HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV‐2 spike (S) glycoprotein warranting further evaluation as an antiviral against COVID‐19 infections
- (2020) Farhana Musarrat et al. JOURNAL OF MEDICAL VIROLOGY
- In Silico Exploration of the Molecular Mechanism of Clinically Oriented Drugs for Possibly Inhibiting SARS-CoV-2’s Main Protease
- (2020) Tien Huynh et al. Journal of Physical Chemistry Letters
- The association between treatment with heparin and survival in patients with Covid-19
- (2020) Luis Ayerbe et al. JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Remdesivir for the Treatment of Covid-19 — Preliminary Report
- (2020) John H. Beigel et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
- (2020) Bin Cao et al. NEW ENGLAND JOURNAL OF MEDICINE
- Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
- (2020) Linlin Zhang et al. SCIENCE
- An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
- (2020) Timothy P. Sheahan et al. Science Translational Medicine
- Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies
- (2020) Jianjun Gao et al. BioScience Trends
- A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease
- (2020) Donald C. Hall et al. Travel Medicine and Infectious Disease
- Gemcitabine, lycorine and oxysophoridine inhibit novel coronavirus (SARS-CoV-2) in cell culture
- (2020) Ya-Nan Zhang et al. Emerging Microbes & Infections
- The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro
- (2020) Xi Wang et al. Cell Discovery
- Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
- (2020) Jia Liu et al. Cell Discovery
- Atazanavir, alone or in combination with ritonavir, inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production
- (2020) Natalia Fintelman-Rodrigues et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro
- (2020) Ka-Tim Choy et al. ANTIVIRAL RESEARCH
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
- (2020) Mehdi Bouhaddou et al. CELL
- In Silico Screening of Potential Spike Glycoprotein Inhibitors of SARS-CoV-2 with Drug Repurposing Strategy
- (2020) Tian-zi Wei et al. Chinese Journal of Integrative Medicine
- In silico study of azithromycin, chloroquine and hydroxychloroquine and their potential mechanisms of action against SARS-CoV-2 infection
- (2020) Helyson Lucas Bezerra Braz et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- SARS‐CoV‐2 and SARS‐CoV: Virtual screening of potential inhibitors targeting RNA‐dependent RNA polymerase activity (NSP12)
- (2020) Zijing Ruan et al. JOURNAL OF MEDICAL VIROLOGY
- Efficacy and safety of umifenovir for coronavirus disease 2019 (COVID‐19): A systematic review and meta‐analysis
- (2020) Dong Huang et al. JOURNAL OF MEDICAL VIROLOGY
- Comparative analysis of antiviral efficacy of FDA‐approved drugs against SARS‐CoV‐2 in human lung cells
- (2020) Meehyun Ko et al. JOURNAL OF MEDICAL VIROLOGY
- Investigating the potential antiviral activity drugs against SARS-CoV-2 by molecular docking simulation
- (2020) A.N. El-hoshoudy JOURNAL OF MOLECULAR LIQUIDS
- Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CLpro targeting repurposed drug candidates
- (2020) Nitin Chitranshi et al. Journal of Translational Medicine
- Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
- (2020) Abdo A. Elfiky LIFE SCIENCES
- In vitro testing of combined hydroxychloroquine and azithromycin on SARS-CoV-2 shows synergistic effect
- (2020) Julien Andreani et al. MICROBIAL PATHOGENESIS
- Antiviral activities of mycophenolic acid and IMD‐0354 against SARS‐CoV‐2
- (2020) Fumihiro Kato et al. MICROBIOLOGY AND IMMUNOLOGY
- In Silico Evaluation of the Effectivity of Approved Protease Inhibitors against the Main Protease of the Novel SARS-CoV-2 Virus
- (2020) Phaedra Eleftheriou et al. MOLECULES
- Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
- (2020) Laura Riva et al. NATURE
- Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates
- (2020) Pauline Maisonnasse et al. NATURE
- A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19
- (2020) David R. Boulware et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner
- (2020) Mizuki Yamamoto et al. Viruses-Basel
- In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication
- (2020) Franck Touret et al. Scientific Reports
- Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice
- (2020) Andrea J. Pruijssers et al. Cell Reports
- Anti-SARS-CoV-2 Potential of Artemisinins In Vitro
- (2020) Ruiyuan Cao et al. ACS Infectious Diseases
- Antiviral Activity and Safety of Darunavir/Cobicistat for the Treatment of COVID-19
- (2020) Jun Chen et al. Open Forum Infectious Diseases
- In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2
- (2020) Andrés Pizzorno et al. ANTIVIRAL RESEARCH
- The potential of low molecular weight heparin to mitigate cytokine storm in severe COVID‐19 patients: a retrospective cohort study
- (2020) Chen Shi et al. CTS-Clinical and Translational Science
- Methylene blue inhibits the replication of SARS-Cov-2 in vitro
- (2020) Mathieu Gendrot et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Antimalarial artemisinin-based combination therapies (ACT) and COVID-19 in Africa: In vitro inhibition of SARS-CoV-2 replication by mefloquine-artesunate
- (2020) Mathieu Gendrot et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Sofosbuvir and daclatasvir compared with standard of care in the treatment of patients admitted to hospital with moderate or severe coronavirus infection (COVID-19): a randomized controlled trial
- (2020) Anahita Sadeghi et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2 In Vitro and SARS-CoV In Vivo
- (2020) Stuart Weston et al. JOURNAL OF VIROLOGY
- Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
- (2020) Peter W Horby et al. LANCET
- Computational insights into tetracyclines as inhibitors against SARS-CoV-2 Mpro via combinatorial molecular simulation calculations
- (2020) Shiv Bharadwaj et al. LIFE SCIENCES
- Anti-HCV and anti-malaria agent, potential candidates to repurpose for coronavirus infection: Virtual screening, molecular docking, and molecular dynamics simulation study
- (2020) Faezeh Sadat Hosseini et al. LIFE SCIENCES
- Drug Repurposing for Candidate SARS-CoV-2 Main Protease Inhibitors by a Novel In Silico Method
- (2020) Milan Sencanski et al. MOLECULES
- Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases
- (2020) Michael K. Lo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection
- (2020) Shin-ichiro Hattori et al. mBio
- Antiviral activity of digoxin and ouabain against SARS-CoV-2 infection and its implication for COVID-19
- (2020) Junhyung Cho et al. Scientific Reports
- Antimalarial drugs inhibit the replication of SARS-CoV-2: An in vitro evaluation
- (2020) Mathieu Gendrot et al. Travel Medicine and Infectious Disease
- Potential COVID-19 papain-like protease PLpro inhibitors: repurposing FDA-approved drugs
- (2020) Valentina L. Kouznetsova et al. PeerJ
- Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations
- (2020) Julia A. Tree et al. BRITISH JOURNAL OF PHARMACOLOGY
- Screening and evaluation of approved drugs as inhibitors of main protease of SARS-CoV-2
- (2020) Praveen Kumar Tripathi et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Sofosbuvir and daclatasvir for the treatment of COVID-19 outpatients: a double-blind, randomized controlled trial
- (2020) Fatemeh Roozbeh et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- High-throughput Screening and Identification of Potent Broad-spectrum Inhibitors of Coronaviruses
- (2019) Liang Shen et al. JOURNAL OF VIROLOGY
- Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir
- (2019) Egor Tchesnokov et al. Viruses-Basel
- Pharmacokinetics of quinine in healthy Nigerian subjects and in patients with uncomplicated malaria: analysis of data using a population approach
- (2019) Ayorinde Adehin et al. CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
- Niclosamide: Beyond an antihelminthic drug
- (2018) Wei Chen et al. CELLULAR SIGNALLING
- Simultaneous quantitation of hydroxychloroquine and its metabolites in mouse blood and tissues using LC–ESI–MS/MS: An application for pharmacokinetic studies
- (2018) Yashpal S. Chhonker et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells
- (2018) Yu Cong et al. PLoS One
- Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
- (2018) Maria L. Agostini et al. mBio
- Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry
- (2018) Shu Yang et al. Cell Discovery
- The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR
- (2018) Jo-Chi Kao et al. PLoS Neglected Tropical Diseases
- Evaluation of cell viability dyes in antiviral assays with RNA viruses that exhibit different cytopathogenic properties
- (2017) Donald F. Smee et al. JOURNAL OF VIROLOGICAL METHODS
- DrugBank 5.0: a major update to the DrugBank database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
- (2017) Timothy P. Sheahan et al. Science Translational Medicine
- Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)
- (2016) Nan Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion
- (2016) Christopher M. Coleman et al. JOURNAL OF VIROLOGY
- Prescribing azithromycin
- (2015) Brendan K McMullan et al. Australian Prescriber
- Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases
- (2015) K. D. Rainsford et al. INFLAMMOPHARMACOLOGY
- Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
- (2014) Adriaan H. de Wilde et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
- (2014) Julie Dyall et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Nitazoxanide: A first-in-class broad-spectrum antiviral agent
- (2014) Jean-François Rossignol ANTIVIRAL RESEARCH
- Mass balance and metabolism of the antimalarial pyronaridine in healthy volunteers
- (2014) Carrie A. Morris et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus
- (2014) Anna Lundin et al. PLoS Pathogens
- Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
- (2013) Jasper F.W. Chan et al. JOURNAL OF INFECTION
- Gender-specific distribution of mefloquine in the blood following the administration of therapeutic doses
- (2013) Walther H Wernsdorfer et al. MALARIA JOURNAL
- Cysteine cathepsins: From structure, function and regulation to new frontiers
- (2011) Vito Turk et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Absorption, Distribution, Excretion, and Pharmacokinetics ofC-Pyronaridine Tetraphosphate in Male and Female Sprague-Dawley Rats
- (2010) Sang Hyun Park et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers
- (2009) Visweswaran Navaratnam et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo
- (2009) Craig W. Day et al. VIROLOGY
- Is the anti-psychotic, 10-(3-(dimethylamino)propyl)phenothiazine (promazine), a potential drug with which to treat SARS infections?
- (2008) Dale L. Barnard et al. ANTIVIRAL RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started