Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry
出版年份 2018 全文链接
标题
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry
作者
关键词
-
出版物
Cell Discovery
Volume 4, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-06-04
DOI
10.1038/s41421-018-0034-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Blocking Zika virus vertical transmission
- (2018) Pinar Mesci et al. Scientific Reports
- Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice
- (2017) Bin Cao et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis
- (2017) Sergey A. Shiryaev et al. Scientific Reports
- Advances in Zika Virus Research: Stem Cell Models, Challenges, and Opportunities
- (2016) Guo-li Ming et al. Cell Stem Cell
- Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design
- (2016) Fumiaki Yokokawa et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Brazilian Zika virus strain causes birth defects in experimental models
- (2016) Fernanda R. Cugola et al. NATURE
- Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
- (2016) Miao Xu et al. NATURE MEDICINE
- Zika Virus Associated with Microcephaly
- (2016) Jernej Mlakar et al. NEW ENGLAND JOURNAL OF MEDICINE
- A cell-based quantitative high-throughput image screening identified novel autophagy modulators
- (2016) Yuan Li et al. PHARMACOLOGICAL RESEARCH
- How do the alkaloids emetine and homoharringtonine kill trypanosomes? An insight into their molecular modes of action
- (2016) Sonja Krstin et al. PHYTOMEDICINE
- Lipids and flaviviruses, present and future perspectives for the control of dengue, Zika, and West Nile viruses
- (2016) Miguel A. Martín-Acebes et al. PROGRESS IN LIPID RESEARCH
- Drug Repurposing: New Treatments for Zika Virus Infection?
- (2016) Feixiong Cheng et al. TRENDS IN MOLECULAR MEDICINE
- Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
- (2016) Siew Pheng Lim et al. PLoS Pathogens
- Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus
- (2016) Rupkatha Mukhopadhyay et al. PLoS Pathogens
- Natural Plant Alkaloid (Emetine) Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity
- (2015) Ana Valadão et al. MOLECULES
- Evaluation of Ebola Virus Inhibitors for Drug Repurposing
- (2015) Peter B. Madrid et al. ACS Infectious Diseases
- High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication
- (2015) Megan R. Edwards et al. ACS Infectious Diseases
- Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
- (2014) Jennifer Kouznetsova et al. Emerging Microbes & Infections
- Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate
- (2013) Holly Matthews et al. MALARIA JOURNAL
- δ-Tocopherol Reduces Lipid Accumulation in Niemann-Pick Type C1 and Wolman Cholesterol Storage Disorders
- (2012) Miao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of Niemann Pick type C proteins 1 and 2 greatly enhances HIV infectivity and is associated with accumulation of HIV Gag and cholesterol in late endosomes/lysosomes
- (2012) Ebony M Coleman et al. Virology Journal
- Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection
- (2011) Marceline Côté et al. NATURE
- Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
- (2011) Jan E. Carette et al. NATURE
- Minigenome-Based Reporter System Suitable for High-Throughput Screening of Compounds Able To Inhibit Ebolavirus Replication and/or Transcription
- (2010) L. D. Jasenosky et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes
- (2009) Monique Gannagé et al. Cell Host & Microbe
- An enzymatic virus-like particle assay for sensitive detection of virus entry
- (2009) Donna M. Tscherne et al. JOURNAL OF VIROLOGICAL METHODS
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