Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
出版年份 2020 全文链接
标题
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
作者
关键词
-
出版物
SCIENCE
Volume -, Issue -, Pages eabb3405
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2020-03-21
DOI
10.1126/science.abb3405
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR
- (2020) Victor M Corman et al. Eurosurveillance
- α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment
- (2020) Linlin Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- A new coronavirus associated with human respiratory disease in China
- (2020) Fan Wu et al. NATURE
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
- (2020) Nature Microbiology
- A G-quadruplex-binding macrodomain within the “SARS-unique domain” is essential for the activity of the SARS-coronavirus replication–transcription complex
- (2015) Yuri Kusov et al. VIROLOGY
- From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design
- (2014) Rolf Hilgenfeld FEBS Journal
- Dynamically-Driven Enhancement of the Catalytic Machinery of the SARS 3C-Like Protease by the S284-T285-I286/A Mutations on the Extra Domain
- (2014) Liangzhong Lim et al. PLoS One
- 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses
- (2013) J. Tan et al. JOURNAL OF VIROLOGY
- JLigand: a graphical tool for theCCP4 template-restraint library
- (2012) Andrey A. Lebedev et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- XDSAPP: a graphical user interface for the convenient processing of diffraction data usingXDS
- (2012) Michael Krug et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin
- (2012) Uwe Mueller et al. JOURNAL OF SYNCHROTRON RADIATION
- Linking Crystallographic Model and Data Quality
- (2012) P. A. Karplus et al. SCIENCE
- An introduction to data reduction: space-group determination, scaling and intensity statistics
- (2011) Philip R. Evans ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- REFMAC5 for the refinement of macromolecular crystal structures
- (2011) Garib N. Murshudov et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease
- (2011) Lili Zhu et al. ANTIVIRAL RESEARCH
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel
- (2010) Yong Zhang et al. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
- Molecular replacement withMOLREP
- (2009) Alexei Vagin et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started