Screening and evaluation of approved drugs as inhibitors of main protease of SARS-CoV-2

Processing of the SARS-CoV pp1a/ab nsp7-10 region

(2020) Boris Krichel et al.   BIOCHEMICAL JOURNAL

Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS‐CoV, MERS‐CoV, and 2019‐nCoV

(2020) Jia Liu et al.   JOURNAL OF MEDICAL VIROLOGY

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

(2020) Guangdi Li et al.   NATURE REVIEWS DRUG DISCOVERY

Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: Possible therapeutic implication in COVID-19

(2020) Anas Shamsi et al.   BIOSCIENCE REPORTS

Teicoplanin: an alternative drug for the treatment of COVID-19?

(2020) Sophie Alexandra Baron et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

(2020) Linlin Zhang et al.   SCIENCE

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2

(2020) Jianzhong Shi et al.   SCIENCE

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

(2020) Chunlong Ma et al.   CELL RESEARCH

Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis

(2020) Giuseppe Lippi et al.   CLINICA CHIMICA ACTA

Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

(2020) Ahmad Abu Turab Naqvi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Halogen Bond Interactions of Novel HIV-1 Protease Inhibitors (PI) (GRL-001-15 and GRL-003-15) with the Flap of Protease Are Critical for Their Potent Activity against Wild-Type HIV-1 and Multi-PI-Resistant Variants

(2019) Shin-ichiro Hattori et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

Pharmacodynamics of teicoplanin against MRSA

(2017) V Ramos-Martín et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)

(2016) Nan Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SARS and MERS: recent insights into emerging coronaviruses

(2016) Emmie de Wit et al.   NATURE REVIEWS MICROBIOLOGY

SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity

(2016) Tomonari Muramatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chalcones isolated fromAngelica keiskeiinhibit cysteine proteases of SARS-CoV

(2015) Ji-Young Park et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Intrinsic Tryptophan Fluorescence in the Detection and Analysis of Proteins: A Focus on Förster Resonance Energy Transfer Techniques

(2014) Amar Ghisaidoobe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CLpro) from its polyproteins

(2013) Tomonari Muramatsu et al.   FEBS Journal

Dynamically-Driven Inactivation of the Catalytic Machinery of the SARS 3C-Like Protease by the N214A Mutation on the Extra Domain

(2011) Jiahai Shi et al.   PLoS Computational Biology

Mutation of Glu-166 Blocks the Substrate-Induced Dimerization of SARS Coronavirus Main Protease

(2010) Shu-Chun Cheng et al.   BIOPHYSICAL JOURNAL

Maturation Mechanism of Severe Acute Respiratory Syndrome (SARS) Coronavirus 3C-like Proteinase

(2010) Chunmei Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of in vitro prophylactic and therapeutic efficacy of chloroquine against chikungunya virus in vero cells

(2010) Mohsin Khan et al.   JOURNAL OF MEDICAL VIROLOGY

Sigma's Non-specific Protease Activity Assay - Casein as a Substrate

(2008) Carrie Cupp-Enyard   Jove-Journal of Visualized Experiments