Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF/TrkA/P75NTR signaling disruption

Bisphenol A exposure is involved in the development of Parkinson like disease in Drosophila melanogaster

(2020) Elize Aparecida Santos Musachio et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective effects of lycopene on hippocampal neurotoxicity and memory impairment induced by bisphenol A in rats

(2020) EM El Morsy et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment

(2020) Paula Moyano et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Impact of estrogen receptor agonists and model of menopause on enzymes involved in brain metabolism, acetyl-CoA production and cholinergic function

(2020) Z.Z. Kirshner et al.   LIFE SCIENCES

Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells

(2020) Zhihong Yin et al.   TOXICOLOGY IN VITRO

Bisphenol A (BPA) Affects the Enteric Nervous System in the Porcine Stomach

(2020) Krystyna Makowska et al.   Animals

ProNGF and Neurodegeneration in Alzheimer’s Disease

(2019) Margaret Fahnestock et al.   Frontiers in Neuroscience

Histone deacetylase inhibitors induce complex host responses that contribute to differential potencies of these compounds in HIV reactivation

(2019) Nadejda Beliakova-Bethell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manganese induced ROS and AChE variants alteration leads to SN56 basal forebrain cholinergic neuronal loss after acute and long-term treatment

(2019) Paula Moyano et al.   FOOD AND CHEMICAL TOXICOLOGY

Neurotoxicity of BPA, BPS, and BPB for the hippocampal cell line (HT-22): An implication for the replacement of BPA in plastics

(2019) Qihua Pang et al.   CHEMOSPHERE

Quantification of eight bisphenol analogues in blood and urine samples of workers in a hazardous waste incinerator

(2019) Neus González et al.   ENVIRONMENTAL RESEARCH

β-Hydroxybutyrate Ameliorates Aβ-Induced Downregulation of TrkA Expression by Inhibiting HDAC1/3 in SH-SY5Y Cells

(2019) Xinhui Li et al.   American Journal of Alzheimers Disease and Other Dementias

The protective effect of α-lipoic acid against bisphenol A-induced neurobehavioral toxicity

(2018) Jasim Khan et al.   NEUROCHEMISTRY INTERNATIONAL

Cadmium induced ROS alters M1 and M3 receptors, leading to SN56 cholinergic neuronal loss, through AChE variants disruption

(2018) Paula Moyano et al.   TOXICOLOGY

Possible Obesogenic Effects of Bisphenols Accumulation in the Human Brain

(2018) Pantelis Charisiadis et al.   Scientific Reports

Vitamin E Inhibits Oxidative Stress-Induced Denaturation of Nerve Terminal Proteins Involved in Neurotransmission

(2018) Nozomi Kaneai et al.   JOURNAL OF ALZHEIMERS DISEASE

HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease

(2018) Laura Mahady et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Bisphenol A exposure remodels cognition of male rats attributable to excitatory alterations in the hippocampus and visual cortex

(2018) Zhi Chen et al.   TOXICOLOGY

Beneficial Effects of Sulforaphane Treatment in Alzheimer's Disease May Be Mediated through Reduced HDAC1/3 and Increased P75NTR Expression

(2017) Jingzhu Zhang et al.   Frontiers in Aging Neuroscience

Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer’s Disease-like Neurotoxicity

(2017) Tingwei Wang et al.   Scientific Reports

Regulation of arcuate genes by developmental exposures to endocrine-disrupting compounds in female rats

(2016) Troy A. Roepke et al.   REPRODUCTIVE TOXICOLOGY

Cognitive Correlates of Basal Forebrain Atrophy and Associated Cortical Hypometabolism in Mild Cognitive Impairment

(2015) Michel J. Grothe et al.   CEREBRAL CORTEX

Low circulating levels of bisphenol-A induce cognitive deficits and loss of asymmetric spine synapses in dorsolateral prefrontal cortex and hippocampus of adult male monkeys

(2015) John D. Elsworth et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A Unique Pattern of Bisphenol A Effects on Nerve Growth Factor Gene Expression in Embryonic Mouse Hypothalamic Cell Line N-44

(2014) Katsuhiko Warita et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

Exposure to Low-Dose Bisphenol A Impairs Meiosis in the Rat Seminiferous Tubule Culture Model: A Physiotoxicogenomic Approach

(2014) Sazan Ali et al.   PLoS One

Neuronal AChE splice variants and their non-hydrolytic functions: redefining a target of AChE inhibitors?

(2013) M Zimmermann   BRITISH JOURNAL OF PHARMACOLOGY

Sex-specific effects of bisphenol-A on memory and synaptic structural modification in hippocampus of adult mice

(2013) Xiaohong Xu et al.   HORMONES AND BEHAVIOR

Exposure to bisphenol-A affects fear memory and histone acetylation of the hippocampus in adult mice

(2013) Qin Zhang et al.   HORMONES AND BEHAVIOR

Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury

(2013) J. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bisphenol S in Urine from the United States and Seven Asian Countries: Occurrence and Human Exposures

(2012) Chunyang Liao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Relation between Pro-inflammatory Cytokines and Acetylcholine Levels in Relapsing-Remitting Multiple Sclerosis Patients

(2012) Marcella Reale et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4

(2012) B. S. Sailaja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholinergic modulation of cognitive processing: insights drawn from computational models

(2012) Ehren L. Newman et al.   Frontiers in Behavioral Neuroscience

Bisphenol-A impairs memory and reduces dendritic spine density in adult male rats.

(2011) Tehila Eilam-Stock et al.   BEHAVIORAL NEUROSCIENCE

Roles of p75NTR in the pathogenesis of Alzheimer's disease: A novel therapeutic target

(2011) Fan Zeng et al.   BIOCHEMICAL PHARMACOLOGY

Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects

(2011) Beverly S. Rubin   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Acetylcholinesterase is involved in apoptosis in the precursors of human muscle regeneration

(2010) Katarina Pegan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dramatic increase in readthrough acetylcholinesterase in a cellular model of oxidative stress

(2010) Ricarda Härtl et al.   JOURNAL OF NEUROCHEMISTRY

Involvement of histone acetylation in the regulation of choline acetyltransferase gene in NG108-15 neuronal cells

(2010) Shu Aizawa et al.   NEUROCHEMISTRY INTERNATIONAL

Acetylcholinesterase Variants in Alzheimer’s Disease: From Neuroprotection to Programmed Cell Death

(2010) David S. Greenberg et al.   Neurodegenerative Diseases

Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation

(2009) Rodrigo R Resende et al.   Cell Communication and Signaling

The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice

(2008) Robert Adamec et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of estrogen on intracellular signaling pathways linked to activation of muscarinic acetylcholine receptors and on acetylcholinesterase activity in rat hippocampus

(2008) Renato Tavares dos Santos Pereira et al.   BIOCHEMICAL PHARMACOLOGY